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B9KMF8 (B9KMF8_RHOSK) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 23. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Serine hydroxymethyltransferase HAMAP MF_00051
Short name=SHMT HAMAP MF_00051
Short name=Serine methylase HAMAP MF_00051
EC=2.1.2.1 HAMAP MF_00051
Gene names
Name:glyA HAMAP MF_00051
Ordered Locus Names:RSKD131_2189
OrganismRhodobacter sphaeroides (strain KD131 / KCTC 12085) [Complete proteome] [HAMAP]
Taxonomic identifier557760 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Alphaproteobacteria › Rhodobacterales › Rhodobacteraceae › Rhodobacter

Protein attributes

Sequence length431 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Interconversion of serine and glycine By similarity. RuleBase RU000585 HAMAP MF_00051

Catalytic activity

5,10-methylenetetrahydrofolate + glycine + H2O = tetrahydrofolate + L-serine. RuleBase RU000585 HAMAP MF_00051

Cofactor

Pyridoxal phosphate By similarity. RuleBase RU000585 HAMAP MF_00051

Pathway

One-carbon metabolism; tetrahydrofolate interconversion. HAMAP MF_00051

One-carbon metabolism; tetrahydrofolate pathway. RuleBase RU000585

Subunit structure

Homotetramer By similarity. HAMAP MF_00051

Subcellular location

Cytoplasm By similarity HAMAP MF_00051.

Sequence similarities

Belongs to the SHMT family. RuleBase RU004104 HAMAP MF_00051

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Amino acid modifications

Modified residue2371N6-(pyridoxal phosphate)lysine By similarity HAMAP MF_00051

Sequences

Sequence LengthMass (Da)Tools
B9KMF8 [UniParc].

Last modified March 24, 2009. Version 1.
Checksum: 566D7223F5F42E74

FASTA43145,736
        10         20         30         40         50         60 
MNAPHRDDGF FTESLSSRDP ELFASITGEL GRQRDEIELI ASENIVSRAV MEAQGSVMTN 

        70         80         90        100        110        120 
KYAEGYAGKR YYGGCDYVDV AETLAIERAK QLFGCAYVNV QPNSGSQANQ GVFQALIKPG 

       130        140        150        160        170        180 
DTILGMELAS GGHLTHGAAP NQSGKWFNAV QYGVRQQDQL IDYDQVAALA REHKPKLIIA 

       190        200        210        220        230        240 
GGSAIPRQID FARFRAIADE VGALLMVDMA HFAGLVAGGA HPSPFPHADV ATTTTHKTLR 

       250        260        270        280        290        300 
GPRGGMILTN SEEIAKKVNS AIFPGIQGGP LMHVIAAKAV AFGEALRPEF KAYAAQVVKN 

       310        320        330        340        350        360 
AQSLADELMK GGLDIVTGGT DTHLMLVDLR PKGVKGNATE KALGRAHITC NKNGIPFDPE 

       370        380        390        400        410        420 
KPTVTSGVRL GTPAGTTRGF GEAEFREIGR LIVEVVDGLA ANGEEGNAAV EEAVKAKVAA 

       430 
LCARFPLYPT L

« Hide

References

[1]"Complete genome sequence of Rhodobacter sphaeroides KD131."
Lim S.-K., Kim S.J., Cha S.H., Oh Y.-K., Rhee H.-J., Kim M.-S., Lee J.K.
J. Bacteriol. 191:1118-1119(2009) [PubMed: 19028901] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP001150 Genomic DNA. Translation: ACM02049.1.
RefSeqYP_002526550.1. NC_011963.1.

3D structure databases

ModBaseSearch...

Protein-protein interaction databases

STRINGB9KMF8.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID7358296.
GenomeReviewsGene locus RSKD131_2189 in contig CP001150_GR.
KEGGrsk:RSKD131_2189.
PATRIC23183499. VBIRhoSph125910_3595.

Organism-specific databases

CMRSearch...

Phylogenomic databases

OMAIFNAGYA.
ProtClustDBPRK00011.

Family and domain databases

HAMAPMF_00051. SHMT.
[Tree]
InterProIPR015424. PyrdxlP-dep_Trfase_major_dom.
IPR015421. PyrdxlP-dep_Trfase_major_sub1.
IPR015422. PyrdxlP-dep_Trfase_major_sub2.
IPR001085. Ser_HO-MeTrfase.
IPR019798. Ser_HO-MeTrfase_PLP_BS.
[Graphical view]
Gene3DG3DSA:3.40.640.10. PyrdxlP-dep_Trfase_major_sub1. 1 hit.
G3DSA:3.90.1150.10. PyrdxlP-dep_Trfase_major_sub2. 1 hit.
KOK00600.
PANTHERPTHR11680. Gly_HO-Metrfase. 1 hit.
PfamPF00464. SHMT. 1 hit.
[Graphical view]
PIRSFPIRSF000412. SHMT. 1 hit.
SUPFAMSSF53383. PyrdxlP-dep_Trfase_major. 1 hit.
PROSITEPS00096. SHMT. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameB9KMF8_RHOSK
AccessionPrimary (citable) accession number: B9KMF8
Entry history
Integrated into UniProtKB/TrEMBL: March 24, 2009
Last sequence update: March 24, 2009
Last modified: December 14, 2011
This is version 23 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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