B9KDQ0 (B9KDQ0_CAMLR) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Lipid-A-disaccharide synthase EMBL ACM64688.1
EC=2.4.1.182 EMBL ACM64688.1

Gene names

Name:	lpxB EMBL ACM64688.1
Ordered Locus Names:	Cla_1373

Organism

Campylobacter lari (strain RM2100 / D67 / ATCC BAA-1060) [Complete proteome] [HAMAP]

Taxonomic identifier

306263 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Epsilonproteobacteria › Campylobacterales › Campylobacteraceae › Campylobacter

Protein attributes

Sequence length	364 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell By similarity. SAAS SAAS003835
Catalytic activity	UDP-2,3-bis(3-hydroxytetradecanoyl)glucosamine + 2,3-bis(3-hydroxytetradecanoyl)-beta-D-glucosaminyl 1-phosphate = UDP + 2,3-bis(3-hydroxytetradecanoyl)-D-glucosaminyl-1,6-beta-D-2,3-bis(3-hydroxytetradecanoyl)-beta-D-glucosaminyl 1-phosphate. SAAS SAAS003835
Pathway	Glycolipid biosynthesis; lipid IV(A) biosynthesis; lipid IV(A) from (3R)-3-hydroxytetradecanoyl-[acyl-carrier-protein] and UDP-N-acetyl-alpha-D-glucosamine: step 5/6. SAAS SAAS003835

Ontologies

Keywords
Biological process	Lipid A biosynthesis SAAS SAAS003835 Lipid synthesis
Molecular function	Glycosyltransferase SAAS SAAS003835 EMBL ACM64688.1 Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	lipid A biosynthetic process Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	lipid-A-disaccharide synthase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	B9KDQ0 [UniParc]. Last modified March 24, 2009. Version 1. Checksum: B3C3EE0D2DF2305C	FASTA	364	41,667
	10 20 30 40 50 60 MKTFLVCALE PSANLHLKEV LKAYKDEYKE FDLVGIYDES LCEEFSLNSK PLYSSHEFSA 70 80 90 100 110 120 MGFIEILPLI FKAKKAIKEL VNLSFEKNIN AILCIDSPAF NIPFAKALKK ANSKIKRIYY 130 140 150 160 170 180 ILPQVWAWKK GRIPIIESYF DVLASILPFD DKFFSKSTYV GHPLLDEIKE FKNEDDIKNI 190 200 210 220 230 240 FSKKDDEKII AFLPGSRKSE IKRLMPIFKD LSAKFNGKKI LCVPEFNLKK LDLYGDISGF 250 260 270 280 290 300 EIQSNTPKVL KNADFAFICS GTATLEAALV GTPFVLAYKA KAIDIFIAKL FVKLKHIGLA 310 320 330 340 350 360 NIFLDFAGKN ELNPEFLQNE VNVKNLYQAY IKYDYKAFFD KVDFLKSYLK FASAKNLAKI LYEI

References

[1]	"The complete genome sequence and analysis of the human pathogen Campylobacter lari." Miller W.G., Wang G., Binnewies T.T., Parker C.T. Foodborne Pathog. Dis. 5:371-386(2008) [PubMed: 18713059] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000932 Genomic DNA. Translation: ACM64688.1.
RefSeq	YP_002575940.1. NC_012039.1.
3D structure databases
ProteinModelPortal	B9KDQ0.
ModBase	Search...
Protein-protein interaction databases
STRING	B9KDQ0.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	7409879.
GenomeReviews	Gene locus Cla_1373 in contig CP000932_GR.
KEGG	cla:Cla_1373.
PATRIC	20063233. VBICamLar15090_1359.
Organism-specific databases
CMR	Search...
Phylogenomic databases
OMA	AEFAFIC.
ProtClustDB	PRK14089.
Family and domain databases
InterPro	IPR003835. Glyco_trans_19. [Graphical view]
KO	K00748.
Pfam	PF02684. LpxB. 1 hit. [Graphical view]
TIGRFAMs	TIGR00215. LpxB. 1 hit.
ProtoNet	Search...

Entry information

Entry name

B9KDQ0_CAMLR

Accession

Primary (citable) accession number: B9KDQ0

Entry history

Integrated into UniProtKB/TrEMBL:	March 24, 2009
Last sequence update:	March 24, 2009
Last modified:	December 14, 2011
This is version 17 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)