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B9KD12 (B9KD12_CAMLR) Unreviewed, UniProtKB/TrEMBL

Last modified January 25, 2012. Version 20. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Delta-aminolevulinic acid dehydratase RuleBase RU000515

EC=4.2.1.24 RuleBase RU000515
Gene names
Name:hemB EMBL ACM64451.1
Ordered Locus Names:Cla_1129
OrganismCampylobacter lari (strain RM2100 / D67 / ATCC BAA-1060) [Complete proteome] [HAMAP]
Taxonomic identifier306263 [NCBI]
Taxonomic lineageBacteriaProteobacteriaEpsilonproteobacteriaCampylobacteralesCampylobacteraceaeCampylobacter

Protein attributes

Sequence length326 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

2 5-aminolevulinate = porphobilinogen + 2 H2O. RuleBase RU000515

Subunit structure

Homooctamer By similarity. PIRSR PIRSR001415-3 RuleBase RU000515

Sequence similarities

Belongs to the ALADH family. RuleBase RU004161

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Active site1961Schiff-base intermediate with substrate By similarity PIRSR PIRSR001415-1
Active site2491Schiff-base intermediate with substrate By similarity PIRSR PIRSR001415-1
Metal binding1191Zinc; catalytic By similarity PIRSR PIRSR001415-3
Metal binding1211Zinc; catalytic By similarity PIRSR PIRSR001415-3
Metal binding1291Zinc; catalytic By similarity PIRSR PIRSR001415-3
Metal binding2341Magnesium By similarity PIRSR PIRSR001415-5
Binding site2061Substrate 1 By similarity PIRSR PIRSR001415-2
Binding site2181Substrate 1 By similarity PIRSR PIRSR001415-2
Binding site2751Substrate 2 By similarity PIRSR PIRSR001415-2
Binding site3141Substrate 2 By similarity PIRSR PIRSR001415-2

Sequences

Sequence LengthMass (Da)Tools
B9KD12 [UniParc].

Last modified March 24, 2009. Version 1.
Checksum: FE5528D6F777DA44

FASTA32636,092
        10         20         30         40         50         60 
MFKRFRRLRL NENIRSLVKE NTLNLDDLIY PLFVVNGTNI KNEIASMPGV FQMSLDEILK 

        70         80         90        100        110        120 
ECEELINLGI KAIILFGVLE SSKKDSCGSD ALNDDGLIAT SLRAIKAKFP NLVVITDLCF 

       130        140        150        160        170        180 
CEYTDHGHCG IIDPKSKSVD NDLTLEISAK QALIHAKNGA DMIAPSGMMD GIIETLRKTL 

       190        200        210        220        230        240 
DENGFENLPI MAYSTKFASA YYGPFRDVAD SAPSYGDRKT YQMDFANGKE ALCESLEDEK 

       250        260        270        280        290        300 
QGADILMVKP ALAYLDVVKD IANHSKLPLC VYNVSGEYAL LKAGQKAGVI DYEKIVLETM 

       310        320 
LAFKRAGAKL IITYHAKEIA KLLNKE 

« Hide

References

[1]"The complete genome sequence and analysis of the human pathogen Campylobacter lari."
Miller W.G., Wang G., Binnewies T.T., Parker C.T.
Foodborne Pathog. Dis. 5:371-386(2008) [PubMed: 18713059] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000932 Genomic DNA. Translation: ACM64451.1.
RefSeqYP_002575702.1. NC_012039.1.

3D structure databases

ProteinModelPortalB9KD12.
ModBaseSearch...

Protein-protein interaction databases

STRINGB9KD12.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID7410863.
GenomeReviewsGene locus Cla_1129 in contig CP000932_GR.
KEGGcla:Cla_1129.
PATRIC20062739. VBICamLar15090_1114.

Organism-specific databases

CMRSearch...

Phylogenomic databases

OMATEAYNEN.
ProtClustDBPRK09283.

Family and domain databases

InterProIPR013785. Aldolase_TIM.
IPR001731. Porphobilinogen_synth.
[Graphical view]
Gene3DG3DSA:3.20.20.70. Aldolase_TIM. 1 hit.
KOK01698.
PANTHERPTHR11458. AlaD_dehydratase. 1 hit.
PfamPF00490. ALAD. 1 hit.
[Graphical view]
PIRSFPIRSF001415. Porphbilin_synth. 1 hit.
PRINTSPR00144. DALDHYDRTASE.
SMARTSM01004. ALAD. 1 hit.
[Graphical view]
PROSITEPS00169. D_ALA_DEHYDRATASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameB9KD12_CAMLR
AccessionPrimary (citable) accession number: B9KD12
Entry history
Integrated into UniProtKB/TrEMBL: March 24, 2009
Last sequence update: March 24, 2009
Last modified: January 25, 2012
This is version 20 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)