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Protein

Arginine--tRNA ligase

Gene

argS

Organism
Campylobacter lari (strain RM2100 / D67 / ATCC BAA-1060)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-tRNA(Arg).UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionAminoacyl-tRNA synthetase, Ligase
Biological processProtein biosynthesis
LigandATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Arginine--tRNA ligaseUniRule annotation (EC:6.1.1.19UniRule annotation)
Alternative name(s):
Arginyl-tRNA synthetaseUniRule annotation
Short name:
ArgRSUniRule annotation
Gene namesi
Name:argSUniRule annotation
Ordered Locus Names:Cla_1087
OrganismiCampylobacter lari (strain RM2100 / D67 / ATCC BAA-1060)
Taxonomic identifieri306263 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaEpsilonproteobacteriaCampylobacteralesCampylobacteraceaeCampylobacter
Proteomesi
  • UP000007727 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10001988811 – 531Arginine--tRNA ligaseAdd BLAST531

Interactioni

Subunit structurei

Monomer.UniRule annotation

Protein-protein interaction databases

STRINGi306263.Cla_1087.

Structurei

3D structure databases

ProteinModelPortaliB9KCX0.
SMRiB9KCX0.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Motifi113 – 123"HIGH" regionAdd BLAST11

Sequence similaritiesi

Belongs to the class-I aminoacyl-tRNA synthetase family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105C75. Bacteria.
COG0018. LUCA.
HOGENOMiHOG000247214.
KOiK01887.
OMAiNKPLHLG.
OrthoDBiPOG091H01RF.

Family and domain databases

CDDicd00671. ArgRS_core. 1 hit.
Gene3Di1.10.730.10. 1 hit.
3.30.1360.70. 1 hit.
3.40.50.620. 1 hit.
HAMAPiMF_00123. Arg_tRNA_synth. 1 hit.
InterProiView protein in InterPro
IPR001412. aa-tRNA-synth_I_CS.
IPR001278. Arg-tRNA-ligase.
IPR005148. Arg-tRNA-synth_N.
IPR035684. ArgRS_core.
IPR008909. DALR_anticod-bd.
IPR014729. Rossmann-like_a/b/a_fold.
IPR009080. tRNAsynth_Ia_anticodon-bd.
PANTHERiPTHR11956. PTHR11956. 1 hit.
PfamiView protein in Pfam
PF03485. Arg_tRNA_synt_N. 1 hit.
PF05746. DALR_1. 1 hit.
PF00750. tRNA-synt_1d. 1 hit.
PRINTSiPR01038. TRNASYNTHARG.
SMARTiView protein in SMART
SM01016. Arg_tRNA_synt_N. 1 hit.
SM00836. DALR_1. 1 hit.
SUPFAMiSSF47323. SSF47323. 1 hit.
SSF55190. SSF55190. 1 hit.
TIGRFAMsiTIGR00456. argS. 1 hit.
PROSITEiView protein in PROSITE
PS00178. AA_TRNA_LIGASE_I. 1 hit.

Sequencei

Sequence statusi: Complete.

B9KCX0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKTLVYKEIK EKLGRDFILE NPKNKNLAHF ATPLAFSLAK ELKQNPMIIA
60 70 80 90 100
NDIVVKLKDC DCFESVEALN GYVNFKLSKA FLNSLATQAL SDSENFAKDD
110 120 130 140 150
KKEQSFLLEY VSANPTGPLH IGHARGAIFG DTLTRVARHL GYKFDTEYYV
160 170 180 190 200
NDAGNQIYLL GLSILLAVKE HCLKEQVQYP DEYYKGEYII DVAKEAFAEF
210 220 230 240 250
EKDFFVEENI PQLALWAKDK MLKIIKQNLA DAKIFIDAYV SETSYYSELE
260 270 280 290 300
NTLKALKEHG GTYEQDGKIW LASSVKGDEK DRVIIKDDGK GTYLAADIVY
310 320 330 340 350
HKDKMSRGYD KCINIWGADH HGYIARMKAA MEFLGHDSQN LEIILAQMVS
360 370 380 390 400
LLKNGEPYKM SKRAGNFILM GDVLEELGSD VLRYIFISKK CDTHLEFDVD
410 420 430 440 450
EFKKEDSSNP VYYINYAHAR IHQVFAKAGK SVDDVMYAKF ESLNEDGMNL
460 470 480 490 500
LFESLNLKAV LNDAFESRSL QKIPDYLKNL ASLFHKFYNE NKVVGSDNED
510 520 530
EFLKLFAICA LSIKIAFALM GIEAKNKMNH D
Length:531
Mass (Da):60,450
Last modified:March 24, 2009 - v1
Checksum:i07083B8485A4A868
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000932 Genomic DNA. Translation: ACM64409.1.
RefSeqiWP_012661792.1. NC_012039.1.

Genome annotation databases

EnsemblBacteriaiACM64409; ACM64409; Cla_1087.
GeneIDi7410821.
KEGGicla:Cla_1087.
PATRICifig|306263.5.peg.1072.

Similar proteinsi

Entry informationi

Entry nameiSYR_CAMLR
AccessioniPrimary (citable) accession number: B9KCX0
Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 28, 2009
Last sequence update: March 24, 2009
Last modified: August 30, 2017
This is version 54 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Aminoacyl-tRNA synthetases
    List of aminoacyl-tRNA synthetase entries
  2. SIMILARITY comments
    Index of protein domains and families