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B9KCX0 (SYR_CAMLR) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 35. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Arginine--tRNA ligase

EC=6.1.1.19
Alternative name(s):
Arginyl-tRNA synthetase
Short name=ArgRS
Gene names
Name:argS
Ordered Locus Names:Cla_1087
OrganismCampylobacter lari (strain RM2100 / D67 / ATCC BAA-1060) [Complete proteome] [HAMAP]
Taxonomic identifier306263 [NCBI]
Taxonomic lineageBacteriaProteobacteriaEpsilonproteobacteriaCampylobacteralesCampylobacteraceaeCampylobacter

Protein attributes

Sequence length531 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-tRNA(Arg). HAMAP-Rule MF_00123

Subunit structure

Monomer By similarity. HAMAP-Rule MF_00123

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00123.

Sequence similarities

Belongs to the class-I aminoacyl-tRNA synthetase family.

Ontologies

Keywords
   Biological processProtein biosynthesis
   Cellular componentCytoplasm
   LigandATP-binding
Nucleotide-binding
   Molecular functionAminoacyl-tRNA synthetase
Ligase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processarginyl-tRNA aminoacylation

Inferred from electronic annotation. Source: UniProtKB-HAMAP

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionATP binding

Inferred from electronic annotation. Source: UniProtKB-HAMAP

arginine-tRNA ligase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 531531Arginine--tRNA ligase HAMAP-Rule MF_00123
PRO_1000198881

Regions

Motif113 – 12311"HIGH" region HAMAP-Rule MF_00123

Sequences

Sequence LengthMass (Da)Tools
B9KCX0 [UniParc].

Last modified March 24, 2009. Version 1.
Checksum: 07083B8485A4A868

FASTA53160,450
        10         20         30         40         50         60 
MKTLVYKEIK EKLGRDFILE NPKNKNLAHF ATPLAFSLAK ELKQNPMIIA NDIVVKLKDC 

        70         80         90        100        110        120 
DCFESVEALN GYVNFKLSKA FLNSLATQAL SDSENFAKDD KKEQSFLLEY VSANPTGPLH 

       130        140        150        160        170        180 
IGHARGAIFG DTLTRVARHL GYKFDTEYYV NDAGNQIYLL GLSILLAVKE HCLKEQVQYP 

       190        200        210        220        230        240 
DEYYKGEYII DVAKEAFAEF EKDFFVEENI PQLALWAKDK MLKIIKQNLA DAKIFIDAYV 

       250        260        270        280        290        300 
SETSYYSELE NTLKALKEHG GTYEQDGKIW LASSVKGDEK DRVIIKDDGK GTYLAADIVY 

       310        320        330        340        350        360 
HKDKMSRGYD KCINIWGADH HGYIARMKAA MEFLGHDSQN LEIILAQMVS LLKNGEPYKM 

       370        380        390        400        410        420 
SKRAGNFILM GDVLEELGSD VLRYIFISKK CDTHLEFDVD EFKKEDSSNP VYYINYAHAR 

       430        440        450        460        470        480 
IHQVFAKAGK SVDDVMYAKF ESLNEDGMNL LFESLNLKAV LNDAFESRSL QKIPDYLKNL 

       490        500        510        520        530 
ASLFHKFYNE NKVVGSDNED EFLKLFAICA LSIKIAFALM GIEAKNKMNH D 

« Hide

References

[1]"The complete genome sequence and analysis of the human pathogen Campylobacter lari."
Miller W.G., Wang G., Binnewies T.T., Parker C.T.
Foodborne Pathog. Dis. 5:371-386(2008) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: RM2100 / D67 / ATCC BAA-1060.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000932 Genomic DNA. Translation: ACM64409.1.
RefSeqYP_002575660.1. NC_012039.1.

3D structure databases

ProteinModelPortalB9KCX0.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING306263.Cla_1087.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaACM64409; ACM64409; Cla_1087.
GeneID7410821.
KEGGcla:Cla_1087.
PATRIC20062655. VBICamLar15090_1072.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0018.
HOGENOMHOG000247214.
KOK01887.
OMAPTHEMER.
OrthoDBEOG6JB13C.

Enzyme and pathway databases

BioCycCLAR306263:GH7X-1085-MONOMER.

Family and domain databases

Gene3D1.10.730.10. 1 hit.
3.30.1360.70. 1 hit.
3.40.50.620. 1 hit.
HAMAPMF_00123. Arg_tRNA_synth.
InterProIPR001412. aa-tRNA-synth_I_CS.
IPR001278. Arg-tRNA-ligase.
IPR005148. Arg-tRNA-synth_N.
IPR008909. DALR_anticod-bd.
IPR014729. Rossmann-like_a/b/a_fold.
IPR009080. tRNAsynth_1a_anticodon-bd.
[Graphical view]
PANTHERPTHR11956. PTHR11956. 1 hit.
PfamPF03485. Arg_tRNA_synt_N. 1 hit.
PF05746. DALR_1. 1 hit.
PF00750. tRNA-synt_1d. 1 hit.
[Graphical view]
PRINTSPR01038. TRNASYNTHARG.
SMARTSM01016. Arg_tRNA_synt_N. 1 hit.
SM00836. DALR_1. 1 hit.
[Graphical view]
SUPFAMSSF47323. SSF47323. 1 hit.
SSF55190. SSF55190. 1 hit.
TIGRFAMsTIGR00456. argS. 1 hit.
PROSITEPS00178. AA_TRNA_LIGASE_I. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameSYR_CAMLR
AccessionPrimary (citable) accession number: B9KCX0
Entry history
Integrated into UniProtKB/Swiss-Prot: July 28, 2009
Last sequence update: March 24, 2009
Last modified: May 14, 2014
This is version 35 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Aminoacyl-tRNA synthetases

List of aminoacyl-tRNA synthetase entries