Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Peptidyl-tRNA hydrolase

Gene

pth

Organism
Thermotoga neapolitana (strain ATCC 49049 / DSM 4359 / NS-E)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.UniRule annotation

Catalytic activityi

N-substituted aminoacyl-tRNA + H2O = N-substituted amino acid + tRNA.UniRule annotation

GO - Molecular functioni

Keywordsi

Molecular functionHydrolase

Names & Taxonomyi

Protein namesi
Recommended name:
Peptidyl-tRNA hydrolaseUniRule annotation (EC:3.1.1.29UniRule annotation)
Short name:
PTHUniRule annotation
Gene namesi
Name:pthUniRule annotation
Ordered Locus Names:CTN_0832
OrganismiThermotoga neapolitana (strain ATCC 49049 / DSM 4359 / NS-E)
Taxonomic identifieri309803 [NCBI]
Taxonomic lineageiBacteriaThermotogaeThermotogalesThermotogaceaeThermotoga
Proteomesi
  • UP000000445 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10001184161 – 186Peptidyl-tRNA hydrolaseAdd BLAST186

Interactioni

Subunit structurei

Monomer.UniRule annotation

Protein-protein interaction databases

STRINGi309803.CTN_0832

Structurei

3D structure databases

SMRiB9K7S5
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the PTH family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4108ZPD Bacteria
COG0193 LUCA
HOGENOMiHOG000004797
KOiK01056
OMAiRYAHTRH
OrthoDBiPOG091H02CU

Family and domain databases

CDDicd00462 PTH, 1 hit
Gene3Di3.40.50.1470, 1 hit
HAMAPiMF_00083 Pept_tRNA_hydro_bact, 1 hit
InterProiView protein in InterPro
IPR001328 Pept_tRNA_hydro
IPR018171 Pept_tRNA_hydro_CS
IPR036416 Pept_tRNA_hydro_sf
PANTHERiPTHR17224 PTHR17224, 1 hit
PfamiView protein in Pfam
PF01195 Pept_tRNA_hydro, 1 hit
SUPFAMiSSF53178 SSF53178, 1 hit
TIGRFAMsiTIGR00447 pth, 1 hit
PROSITEiView protein in PROSITE
PS01195 PEPT_TRNA_HYDROL_1, 1 hit
PS01196 PEPT_TRNA_HYDROL_2, 1 hit

Sequencei

Sequence statusi: Complete.

B9K7S5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVVVGLGNPG PRYAFTRHNV GFLFLDYLKS KGWKSEKFFE WNKTELDGHE
60 70 80 90 100
IVLVKPLTYM NLSGVAMPYI MRFFRVNVDD IIVVYDDVSL KLGKIRIRKK
110 120 130 140 150
GSDGGHNGMK SIIQALGTQE IKRIRIGIGE KPEGMNLVDF VLGEFSEEEF
160 170 180
KVLQKVFELS RNALVTILNE GIDKAMSVYN SLEVRV
Length:186
Mass (Da):21,148
Last modified:March 24, 2009 - v1
Checksum:iEFFCEE2EC47182EF
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000916 Genomic DNA Translation: ACM23008.1
RefSeqiWP_015919325.1, NC_011978.1

Genome annotation databases

EnsemblBacteriaiACM23008; ACM23008; CTN_0832
KEGGitna:CTN_0832

Similar proteinsi

Entry informationi

Entry nameiPTH_THENN
AccessioniPrimary (citable) accession number: B9K7S5
Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 28, 2009
Last sequence update: March 24, 2009
Last modified: May 23, 2018
This is version 52 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Cookie policy

We would like to use anonymized google analytics cookies to gather statistics on how uniprot.org is used in aggregate. Learn more

UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health