B9K6Z3 (TRPF_THENN) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
N-(5'-phosphoribosyl)anthranilate isomerase
Short name=PRAI
EC=5.3.1.24

Gene names

Name:	trpF
Ordered Locus Names:	CTN_0550

Organism

Thermotoga neapolitana (strain ATCC 49049 / DSM 4359 / NS-E) [Complete proteome] [HAMAP]

Taxonomic identifier

309803 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Thermotogae › Thermotogae › Thermotogales › Thermotogaceae › Thermotoga › Thermotoga neapolitana

Protein attributes

Sequence length	205 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	N-(5-phospho-beta-D-ribosyl)anthranilate = 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate. HAMAP-Rule MF_00135
Pathway	Amino-acid biosynthesis; L-tryptophan biosynthesis; L-tryptophan from chorismate: step 3/5. HAMAP-Rule MF_00135
Sequence similarities	Belongs to the TrpF family.

Ontologies

Keywords
Biological process	Amino-acid biosynthesis Aromatic amino acid biosynthesis Tryptophan biosynthesis
Molecular function	Isomerase
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	tryptophan biosynthetic process Inferred from electronic annotation. Source: HAMAP
Molecular_function	phosphoribosylanthranilate isomerase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 205	205	N-(5'-phosphoribosyl)anthranilate isomerase HAMAP-Rule MF_00135		PRO_1000197134

Sequences

	Sequence		Length	Mass (Da)
	B9K6Z3 [UniParc]. Last modified March 24, 2009. Version 1. Checksum: C818FF3BE5F80799	FASTA	205	22,914
	10 20 30 40 50 60 MVRVKICGIT NLEDALFSVE SGADAVGFVF YSKSKRYVSP EKAREISLNL PPFVFRVGVF 70 80 90 100 110 120 VNESLESVLD IAFHAGLNAV QLHGDESVEF CERLNEKIMV IKAVGISEEQ DVRRALEYRK 130 140 150 160 170 180 FPVLLDTKVS GYGGSGKVFN WSVVLPYRDQ FRYLILSGGL NPRNVERAIE MVRPFAVDVS 190 200 SGVEISPGKK DHNLVREFIK KAKGL

References

[1]

"The genome sequence of the hyperthermophilic bacterium Thermotoga neapolitana." Lim S.K., Kim J.S., Cha S.H., Park B.C., Lee D.S., Tae H.S., Kim S.-J., Kim J.J., Park K.J., Lee S.Y. Submitted (NOV-2007) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 49049 / DSM 4359 / NS-E.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000916 Genomic DNA. Translation: ACM22726.1.
RefSeq	YP_002534092.1. NC_011978.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	309803.CTN_0550.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	ACM22726; ACM22726; CTN_0550.
GeneID	7378934.
KEGG	tna:CTN_0550.
PATRIC	23939885. VBITheNea118396_0543.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0135.
HOGENOM	HOG000161598.
KO	K01817.
ProtClustDB	PRK01222.
Enzyme and pathway databases
UniPathway	UPA00035; UER00042.
Family and domain databases
Gene3D	3.20.20.70. 1 hit.
HAMAP	MF_00135. PRAI.
InterPro	IPR013785. Aldolase_TIM. IPR001240. PRAI. IPR011060. RibuloseP-bd_barrel. [Graphical view]
Pfam	PF00697. PRAI. 1 hit. [Graphical view]
SUPFAM	SSF51366. RibP_bind_barrel. 1 hit.
ProtoNet	Search...

Entry information

Entry name

TRPF_THENN

Accession

Primary (citable) accession number: B9K6Z3

Entry history

Integrated into UniProtKB/Swiss-Prot:	July 28, 2009
Last sequence update:	March 24, 2009
Last modified:	May 1, 2013
This is version 27 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program