B9JXE6 (SYR_AGRVS) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Arginine--tRNA ligase
EC=6.1.1.19

Alternative name(s):
Arginyl-tRNA synthetase
Short name=ArgRS

Gene names

Name:	argS
Ordered Locus Names:	Avi_2675

Organism

Agrobacterium vitis (strain S4 / ATCC BAA-846) (Rhizobium vitis (strain S4)) [Complete proteome] [HAMAP]

Taxonomic identifier

311402 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Rhizobiaceae › Rhizobium/Agrobacterium group › Agrobacterium › Agrobacterium vitis

Protein attributes

Sequence length	585 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-tRNA(Arg). HAMAP-Rule MF_00123
Subunit structure	Monomer By similarity.
Subcellular location	Cytoplasm By similarity.
Sequence similarities	Belongs to the class-I aminoacyl-tRNA synthetase family.

Ontologies

Keywords
Biological process	Protein biosynthesis
Cellular component	Cytoplasm
Ligand	ATP-binding Nucleotide-binding
Molecular function	Aminoacyl-tRNA synthetase Ligase
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	arginyl-tRNA aminoacylation Inferred from electronic annotation. Source: HAMAP
Cellular_component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular_function	ATP binding Inferred from electronic annotation. Source: HAMAP arginine-tRNA ligase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 585	585	Arginine--tRNA ligase HAMAP-Rule MF_00123		PRO_1000198867
Regions
	Motif	131 – 141	11	"HIGH" region HAMAP-Rule MF_00123

Sequences

	Sequence		Length	Mass (Da)
	B9JXE6 [UniParc]. Last modified March 24, 2009. Version 1. Checksum: DAA3F80F6B2ABDAA	FASTA	585	64,890
	10 20 30 40 50 60 MNLFADFENR IKTALETLDL VKEKRSELSF DRIVVEPPRD ASHGDAATNA AMVLAKPLGV 70 80 90 100 110 120 SPRVLADLIG EKLKEDADIA EVSVAGPGFL NIRLSVAYWQ RLLANVIAGG TDFGRSQTGA 130 140 150 160 170 180 GRKVNVEYVS ANPTGPMHVG HCRGAVVGDA LANLLAFAGY GVTKEYYIND AGSQIDVLAR 190 200 210 220 230 240 SVFLRYREAL GEAVGEIPAG LYPGDYLIPV GEALAQEYGV RLHNMPEEQW MEIVKDRAID 250 260 270 280 290 300 AMMVMIREDL AALNVHHDLF YSERQLHANG AAAIRTAIND LTFKGHVYRG TLPPPKGQLP 310 320 330 340 350 360 EDWEDREQTL FRSTEVGDDI DRPLIKSDGS YTYFAADVAY FKDKYDRGFD RMIYVLGADH 370 380 390 400 410 420 GGYVKRLEAV AKAVSEGKAK LTVLLCQLVK LYRDGEPVKM SKRSGDFVTL RDVVEEVGRD 430 440 450 460 470 480 SVRFMMLYRK SSEPLDFDFA KVTEQSKDNP VFYVQYAHAR CMSIFRQARE AFGDIDLSPD 490 500 510 520 530 540 VLEAAVTGIT EPSEVQLIAK LAEYPRIIEA SAQSMEPHRI AFYLYDLASS FHAHWNKGKD 550 560 570 580 QPELRFVNDK NRQSSLARLG LVHAVASVLQ SGLAITGTDA PQEMR

References

[1]

"Genome sequences of three Agrobacterium biovars help elucidate the evolution of multichromosome genomes in bacteria." Slater S.C., Goldman B.S., Goodner B., Setubal J.C., Farrand S.K., Nester E.W., Burr T.J., Banta L., Dickerman A.W., Paulsen I., Otten L., Suen G., Welch R., Almeida N.F., Arnold F., Burton O.T., Du Z., Ewing A. , Godsy E., Heisel S., Houmiel K.L., Jhaveri J., Lu J., Miller N.M., Norton S., Chen Q., Phoolcharoen W., Ohlin V., Ondrusek D., Pride N., Stricklin S.L., Sun J., Wheeler C., Wilson L., Zhu H., Wood D.W. J. Bacteriol. 191:2501-2511(2009) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: S4 / ATCC BAA-846.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000633 Genomic DNA. Translation: ACM36924.1.
RefSeq	YP_002549932.1. NC_011989.1.
3D structure databases
ProteinModelPortal	B9JXE6.
ModBase	Search...
Protein-protein interaction databases
STRING	311402.Avi_2675.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	ACM36924; ACM36924; Avi_2675.
GeneID	7388344.
KEGG	avi:Avi_2675.
PATRIC	20829422. VBIAgrVit37146_4364.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0018.
HOGENOM	HOG000247214.
KO	K01887.
OMA	HTSANPN.
ProtClustDB	PRK01611.
Enzyme and pathway databases
BioCyc	AVIT311402:GH2Y-2074-MONOMER.
Family and domain databases
Gene3D	3.30.1360.70. 1 hit. 3.40.50.620. 1 hit.
HAMAP	MF_00123. Arg_tRNA_synth.
InterPro	IPR001412. aa-tRNA-synth_I_CS. IPR001278. Arg-tRNA-ligase_Ia. IPR015945. Arg-tRNA-synth_Ia_core. IPR005148. Arg-tRNA-synth_N. IPR008909. DALR_anticod-bd. IPR014729. Rossmann-like_a/b/a_fold. IPR009080. tRNAsynth_1a_anticodon-bd. [Graphical view]
PANTHER	PTHR11956. PTHR11956. 1 hit.
Pfam	PF03485. Arg_tRNA_synt_N. 1 hit. PF05746. DALR_1. 1 hit. PF00750. tRNA-synt_1d. 1 hit. [Graphical view]
PRINTS	PR01038. TRNASYNTHARG.
SMART	SM01016. Arg_tRNA_synt_N. 1 hit. SM00836. DALR_1. 1 hit. [Graphical view]
SUPFAM	SSF55190. Arg-tRNA-synth_Ic_N. 1 hit. SSF47323. tRNAsyn_1a_bind. 1 hit.
TIGRFAMs	TIGR00456. argS. 1 hit.
PROSITE	PS00178. AA_TRNA_LIGASE_I. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

SYR_AGRVS

Accession

Primary (citable) accession number: B9JXE6

Entry history

Integrated into UniProtKB/Swiss-Prot:	July 28, 2009
Last sequence update:	March 24, 2009
Last modified:	May 1, 2013
This is version 29 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program