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B9JUY3

- PUR5_AGRVS

UniProt

B9JUY3 - PUR5_AGRVS

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Protein
Phosphoribosylformylglycinamidine cyclo-ligase
Gene
purM, Avi_1575
Organism
Agrobacterium vitis (strain S4 / ATCC BAA-846) (Rhizobium vitis (strain S4))
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + 2-(formamido)-N(1)-(5-phospho-D-ribosyl)acetamidine = ADP + phosphate + 5-amino-1-(5-phospho-D-ribosyl)imidazole.UniRule annotation

Pathwayi

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. phosphoribosylformylglycinamidine cyclo-ligase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. 'de novo' IMP biosynthetic process Source: UniProtKB-UniPathway
Complete GO annotation...

Keywords - Molecular functioni

Ligase

Keywords - Biological processi

Purine biosynthesis

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciAVIT311402:GH2Y-1192-MONOMER.
UniPathwayiUPA00074; UER00129.

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphoribosylformylglycinamidine cyclo-ligase (EC:6.3.3.1)
Alternative name(s):
AIR synthase
AIRS
Phosphoribosyl-aminoimidazole synthetase
Gene namesi
Name:purM
Ordered Locus Names:Avi_1575
OrganismiAgrobacterium vitis (strain S4 / ATCC BAA-846) (Rhizobium vitis (strain S4))
Taxonomic identifieri311402 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesRhizobiaceaeRhizobium/Agrobacterium groupAgrobacterium
ProteomesiUP000001596: Chromosome 1

Subcellular locationi

Cytoplasm By similarity UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 357357Phosphoribosylformylglycinamidine cyclo-ligaseUniRule annotation
PRO_1000148261Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi311402.Avi_1575.

Structurei

3D structure databases

ProteinModelPortaliB9JUY3.

Family & Domainsi

Sequence similaritiesi

Belongs to the AIR synthase family.

Phylogenomic databases

eggNOGiCOG0150.
HOGENOMiHOG000229090.
KOiK01933.
OMAiEFEMYRT.
OrthoDBiEOG61CM1V.

Family and domain databases

Gene3Di3.30.1330.10. 1 hit.
3.90.650.10. 1 hit.
HAMAPiMF_00741_B. AIRS_B.
InterProiIPR010918. AIR_synth_C_dom.
IPR000728. AIR_synth_N_dom.
IPR004733. PurM_cligase.
IPR016188. PurM_N-like.
[Graphical view]
PfamiPF00586. AIRS. 1 hit.
PF02769. AIRS_C. 1 hit.
[Graphical view]
SUPFAMiSSF55326. SSF55326. 1 hit.
SSF56042. SSF56042. 1 hit.
TIGRFAMsiTIGR00878. purM. 1 hit.

Sequencei

Sequence statusi: Complete.

B9JUY3-1 [UniParc]FASTAAdd to Basket

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MSKSGKNGLT YSDAGVDIDA GNLLVEKIKP AVRSTRRPGA DGEIGGFGGL    50
FDLKAAGFTD PILVAANDGV GTKLKIAIDA GLHDTVGIDL VAMCVNDLVV 100
QGAEPLLFLD YYATGKLDPN QGAAIVGGIA AGCREAGCAL IGGETAEMPG 150
MYSGGDYDLA GFAVGAAERG QLLPAGDIAE GDVILGLASS GVHSNGFSLV 200
RKIVELAGLG WDAPAPFAEG ATLGAALLTP TRIYVKPLLK AIRETKALKA 250
LAHITGGGFP ENIPRVLPKH LAAEIDLASI TVPTVFSWLS KTGGVAQNEM 300
LRTFNCGVGM IVVVAAENAD AVAAALEAEG ETVARLGRMI SREEGAPGTV 350
YKGTLGL 357
Length:357
Mass (Da):36,338
Last modified:March 24, 2009 - v1
Checksum:i899C3496C5785CFC
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000633 Genomic DNA. Translation: ACM36128.1.
RefSeqiWP_015915552.1. NC_011989.1.
YP_002549134.1. NC_011989.1.

Genome annotation databases

EnsemblBacteriaiACM36128; ACM36128; Avi_1575.
GeneIDi7387380.
KEGGiavi:Avi_1575.
PATRICi20827636. VBIAgrVit37146_3489.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000633 Genomic DNA. Translation: ACM36128.1 .
RefSeqi WP_015915552.1. NC_011989.1.
YP_002549134.1. NC_011989.1.

3D structure databases

ProteinModelPortali B9JUY3.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 311402.Avi_1575.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ACM36128 ; ACM36128 ; Avi_1575 .
GeneIDi 7387380.
KEGGi avi:Avi_1575.
PATRICi 20827636. VBIAgrVit37146_3489.

Phylogenomic databases

eggNOGi COG0150.
HOGENOMi HOG000229090.
KOi K01933.
OMAi EFEMYRT.
OrthoDBi EOG61CM1V.

Enzyme and pathway databases

UniPathwayi UPA00074 ; UER00129 .
BioCyci AVIT311402:GH2Y-1192-MONOMER.

Family and domain databases

Gene3Di 3.30.1330.10. 1 hit.
3.90.650.10. 1 hit.
HAMAPi MF_00741_B. AIRS_B.
InterProi IPR010918. AIR_synth_C_dom.
IPR000728. AIR_synth_N_dom.
IPR004733. PurM_cligase.
IPR016188. PurM_N-like.
[Graphical view ]
Pfami PF00586. AIRS. 1 hit.
PF02769. AIRS_C. 1 hit.
[Graphical view ]
SUPFAMi SSF55326. SSF55326. 1 hit.
SSF56042. SSF56042. 1 hit.
TIGRFAMsi TIGR00878. purM. 1 hit.
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: S4 / ATCC BAA-846.

Entry informationi

Entry nameiPUR5_AGRVS
AccessioniPrimary (citable) accession number: B9JUY3
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 28, 2009
Last sequence update: March 24, 2009
Last modified: September 3, 2014
This is version 39 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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