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Protein

Phosphoglycerate kinase

Gene

pgk

Organism
Agrobacterium vitis (strain S4 / ATCC BAA-846) (Rhizobium vitis (strain S4))
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + 3-phospho-D-glycerate = ADP + 3-phospho-D-glyceroyl phosphate.UniRule annotation

Pathwayi: glycolysis

This protein is involved in step 2 of the subpathway that synthesizes pyruvate from D-glyceraldehyde 3-phosphate.UniRule annotation
Proteins known to be involved in the 5 steps of the subpathway in this organism are:
  1. no protein annotated in this organism
  2. Phosphoglycerate kinase (pgk)
  3. 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase (gpmA)
  4. Enolase (eno)
  5. Pyruvate kinase (Avi_5923), Pyruvate kinase (pykA), Pyruvate kinase (pykA), Pyruvate kinase (pykA)
This subpathway is part of the pathway glycolysis, which is itself part of Carbohydrate degradation.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes pyruvate from D-glyceraldehyde 3-phosphate, the pathway glycolysis and in Carbohydrate degradation.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei38SubstrateUniRule annotation1
Binding sitei120SubstrateUniRule annotation1
Binding sitei153SubstrateUniRule annotation1
Binding sitei203ATPUniRule annotation1
Binding sitei325ATPUniRule annotation1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi355 – 358ATPUniRule annotation4

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionKinase, Transferase
Biological processGlycolysis
LigandATP-binding, Nucleotide-binding

Enzyme and pathway databases

UniPathwayiUPA00109; UER00185

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphoglycerate kinaseUniRule annotation (EC:2.7.2.3UniRule annotation)
Gene namesi
Name:pgkUniRule annotation
Ordered Locus Names:Avi_3651
OrganismiAgrobacterium vitis (strain S4 / ATCC BAA-846) (Rhizobium vitis (strain S4))
Taxonomic identifieri311402 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesRhizobiaceaeRhizobium/Agrobacterium groupAgrobacterium
Proteomesi
  • UP000001596 Componenti: Chromosome 1

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10002033171 – 400Phosphoglycerate kinaseAdd BLAST400

Interactioni

Subunit structurei

Monomer.UniRule annotation

Protein-protein interaction databases

STRINGi311402.Avi_3651

Structurei

3D structure databases

SMRiB9JS00
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni23 – 25Substrate bindingUniRule annotation3
Regioni61 – 64Substrate bindingUniRule annotation4

Sequence similaritiesi

Belongs to the phosphoglycerate kinase family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105BZA Bacteria
COG0126 LUCA
HOGENOMiHOG000227107
KOiK00927
OMAiDMIFDIG
OrthoDBiPOG091H00YN

Family and domain databases

Gene3Di3.40.50.1260, 3 hits
HAMAPiMF_00145 Phosphoglyc_kinase, 1 hit
InterProiView protein in InterPro
IPR001576 Phosphoglycerate_kinase
IPR015911 Phosphoglycerate_kinase_CS
IPR015824 Phosphoglycerate_kinase_N
IPR036043 Phosphoglycerate_kinase_sf
PANTHERiPTHR11406 PTHR11406, 1 hit
PfamiView protein in Pfam
PF00162 PGK, 1 hit
PIRSFiPIRSF000724 Pgk, 1 hit
PRINTSiPR00477 PHGLYCKINASE
SUPFAMiSSF53748 SSF53748, 1 hit
PROSITEiView protein in PROSITE
PS00111 PGLYCERATE_KINASE, 1 hit

Sequencei

Sequence statusi: Complete.

B9JS00-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPAFKTLDDL TDIAGKRVLL RVDLNVPVSG GKVTDATRIE RVAPTIKELS
60 70 80 90 100
AKGAKVILLA HFGRPKGEPV ADMSLSQIIS AVEEVLDQAV AFGEDCVGEP
110 120 130 140 150
AERAVAALNN GDILLLENTR FHKGEEKNDA DFTAELAKNG DIYVNDAFSA
160 170 180 190 200
AHRAHASTEG LAHILPAYAG RTMQAELEAL EKGLGKPTHP VVAIVGGAKV
210 220 230 240 250
SSKIDLLMNL VKKVDALVIG GGMANTFIAA QGIDVGKSLC EHDLAATAKQ
260 270 280 290 300
IMIEAETAGC TIVLPVDGVV AREFKANAAN ETVSVSAIPA DAMMLDVGPK
310 320 330 340 350
SVAVVNDWIT KAATLVWNGP LGAFEIPPFD TATVSAAKHA AERSKAGKLV
360 370 380 390 400
SVAGGGDTVS ALNHAGVVDD FSYVSTAGGA FLEWMEGKEL PGVAVLTRPA
Length:400
Mass (Da):41,557
Last modified:March 24, 2009 - v1
Checksum:i8047B17EE5C0B540
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000633 Genomic DNA Translation: ACM37628.1
RefSeqiWP_015917041.1, NC_011989.1

Genome annotation databases

EnsemblBacteriaiACM37628; ACM37628; Avi_3651
GeneIDi31496536
KEGGiavi:Avi_3651

Similar proteinsi

Entry informationi

Entry nameiPGK_AGRVS
AccessioniPrimary (citable) accession number: B9JS00
Entry historyiIntegrated into UniProtKB/Swiss-Prot: September 22, 2009
Last sequence update: March 24, 2009
Last modified: May 23, 2018
This is version 53 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health