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B9JH96 (B9JH96_AGRRK) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 15. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
6,7-dimethyl-8-ribityllumazine synthase 2 HAMAP MF_00178
Short name=DMRL synthase 2 HAMAP MF_00178
Short name=Lumazine synthase 2 HAMAP MF_00178
EC=2.5.1.9 HAMAP MF_00178
Alternative name(s):
Riboflavin synthase beta chain 2 HAMAP MF_00178
Gene names
Name:ribH2 HAMAP MF_00178 EMBL ACM27093.1
Ordered Locus Names:Arad_3053
OrganismAgrobacterium radiobacter (strain K84 / ATCC BAA-868) [Complete proteome] [HAMAP]
Taxonomic identifier311403 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Rhizobiaceae › Rhizobium/Agrobacterium group › Agrobacterium

Protein attributes

Sequence length158 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Riboflavin synthase is a bifunctional enzyme complex catalyzing the formation of riboflavin from 5-amino-6-(1'-D)-ribityl-amino-2,4(1H,3H)-pyrimidinedione and L-3,4-dihydrohy-2-butanone-4-phosphate via 6,7-dimethyl-8-lumazine. The beta subunit catalyzes the condensation of 5-amino-6-(1'-D)-ribityl-amino-2,4(1H,3H)-pyrimidinedione with L-3,4-dihydrohy-2-butanone-4-phosphate yielding 6,7-dimethyl-8-lumazine By similarity. HAMAP MF_00178

Catalytic activity

2 6,7-dimethyl-8-(1-D-ribityl)lumazine = riboflavin + 4-(1-D-ribitylamino)-5-amino-2,6-dihydroxypyrimidine. HAMAP MF_00178

Pathway

Cofactor biosynthesis; riboflavin biosynthesis; riboflavin from 2-hydroxy-3-oxobutyl phosphate and 5-amino-6-(D-ribitylamino)uracil: step 2/2. HAMAP MF_00178

Sequence similarities

Belongs to the DMRL synthase family. HAMAP MF_00178

Ontologies

Keywords
   Biological processRiboflavin biosynthesis HAMAP MF_00178
   Molecular functionTransferase HAMAP MF_00178
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processriboflavin biosynthetic process

Inferred from electronic annotation. Source: HAMAP

   Cellular componentriboflavin synthase complex

Inferred from electronic annotation. Source: InterPro

   Molecular functionriboflavin synthase activity

Inferred from electronic annotation. Source: HAMAP

Complete GO annotation...

Sequences

Sequence LengthMass (Da)Tools
B9JH96 [UniParc].

Last modified March 24, 2009. Version 1.
Checksum: 483594BF4174731F

FASTA15817,501
        10         20         30         40         50         60 
MTISISTQPG RIALIRARWH ADIVDQSVDS FIAEWQKTEG ASPIDIFDVP GALEIPLHAQ 

        70         80         90        100        110        120 
TLARNGRYSA IVATAFVVDG GIYRHEFVAN TVLDAMMRVQ LDTGVPILSA VLTPHHFQES 

       130        140        150 
EAHIQFFKEH FVLKGREVAN SCRQILAERA KLLPSVTV

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000628 Genomic DNA. Translation: ACM27093.1.
RefSeqYP_002545023.1. NC_011985.1.

3D structure databases

ModBaseSearch...

Protein-protein interaction databases

STRINGB9JH96.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID7369057.
GenomeReviewsGene locus Arad_3053 in contig CP000628_GR.
KEGGara:Arad_3053.
PATRIC20805569. VBIAgrRad129173_4866.

Organism-specific databases

CMRSearch...

Phylogenomic databases

OMARRYTAIV.
ProtClustDBPRK12419.

Family and domain databases

HAMAPMF_00178. Lumazine_synth.
[Tree]
InterProIPR002180. DMRL_synthase.
[Graphical view]
Gene3DG3DSA:3.40.50.960. DMRL_synthase. 1 hit.
KOK00794.
PANTHERPTHR21058. DMRL_synthase. 1 hit.
PfamPF00885. DMRL_synthase. 1 hit.
[Graphical view]
SUPFAMSSF52121. DMRL_synthase. 1 hit.
ProtoNetSearch...

Entry information

Entry nameB9JH96_AGRRK
AccessionPrimary (citable) accession number: B9JH96
Entry history
Integrated into UniProtKB/TrEMBL: March 24, 2009
Last sequence update: March 24, 2009
Last modified: December 14, 2011
This is version 15 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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