B9JEH2 (SURE_AGRRK) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
5'-nucleotidase surE
EC=3.1.3.5

Alternative name(s):
Nucleoside 5'-monophosphate phosphohydrolase

Gene names

Name:	surE
Ordered Locus Names:	Arad_2132

Organism

Agrobacterium radiobacter (strain K84 / ATCC BAA-868) [Complete proteome] [HAMAP]

Taxonomic identifier

311403 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Rhizobiaceae › Rhizobium/Agrobacterium group › Agrobacterium

Protein attributes

Sequence length	257 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates By similarity. HAMAP MF_00060
Catalytic activity	A 5'-ribonucleotide + H2O = a ribonucleoside + phosphate. HAMAP MF_00060
Cofactor	Binds 1 divalent metal cation per subunit By similarity.
Subcellular location	Cytoplasm Potential HAMAP MF_00060.
Sequence similarities	Belongs to the surE nucleotidase family.

Ontologies

Keywords
Cellular component	Cytoplasm
Ligand	Metal-binding Nucleotide-binding
Molecular function	Hydrolase
Technical term	Complete proteome
Gene Ontology (GO)
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	5'-nucleotidase activity Inferred from electronic annotation. Source: EC metal ion binding Inferred from electronic annotation. Source: UniProtKB-KW nucleotide binding Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 257	257	5'-nucleotidase surE HAMAP MF_00060		PRO_1000196579
Sites
	Metal binding	8	1	Divalent metal cation By similarity
	Metal binding	9	1	Divalent metal cation By similarity
	Metal binding	40	1	Divalent metal cation By similarity
	Metal binding	92	1	Divalent metal cation By similarity

Sequences

	Sequence		Length	Mass (Da)
	B9JEH2 [UniParc]. Last modified March 24, 2009. Version 1. Checksum: 4F07D4B0B1D1E99D	FASTA	257	28,003
	10 20 30 40 50 60 MRILLTNDDG IHAEGLAALE RIARTMSDDV WIVAPETDQS GLAHSLSLSE PLRLRKVSDK 70 80 90 100 110 120 HYALRGTPTD CVIMGIRQVM DIKPDLILSG VNSGSNVADD VTYSGTIAGA IEGTLQGVRS 130 140 150 160 170 180 FALSQAYVHE NGTRVVPWEV VQAHAPALLG KLIDIDLPDG TFLNLNFPNC RPDEVSGTEV 190 200 210 220 230 240 TAQGNLAFNL QVDERADGRG FPYYWLRFGE RSGIFRPGTD IHALKQNRIS VTPLKLDLTD 250 YSVQDRVARA LGHGVAD

References

[1]

"Genome sequences of three Agrobacterium biovars help elucidate the evolution of multichromosome genomes in bacteria." Slater S.C., Goldman B.S., Goodner B., Setubal J.C., Farrand S.K., Nester E.W., Burr T.J., Banta L., Dickerman A.W., Paulsen I., Otten L., Suen G., Welch R., Almeida N.F., Arnold F., Burton O.T., Du Z., Ewing A. , Godsy E., Heisel S., Houmiel K.L., Jhaveri J., Lu J., Miller N.M., Norton S., Chen Q., Phoolcharoen W., Ohlin V., Ondrusek D., Pride N., Stricklin S.L., Sun J., Wheeler C., Wilson L., Zhu H., Wood D.W. J. Bacteriol. 191:2501-2511(2009) [PubMed: 19251847] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: K84 / ATCC BAA-868.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000628 Genomic DNA. Translation: ACM26393.1.
RefSeq	YP_002544319.1. NC_011985.1.
3D structure databases
ProteinModelPortal	B9JEH2.
ModBase	Search...
Protein-protein interaction databases
STRING	B9JEH2.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	7368840.
GenomeReviews	Gene locus Arad_2132 in contig CP000628_GR.
KEGG	ara:Arad_2132.
PATRIC	20804064. VBIAgrRad129173_4125.
Organism-specific databases
CMR	Search...
Phylogenomic databases
OMA	EVWTVAP.
ProtClustDB	PRK00346.
Family and domain databases
HAMAP	MF_00060. SurE. [Tree]
InterPro	IPR002828. SurE-like_Pase/nucleotidase. [Graphical view]
Gene3D	G3DSA:3.40.1210.10. SurE-like_Pase/nucleotidase. 1 hit.
KO	K03787.
Pfam	PF01975. SurE. 1 hit. [Graphical view]
SUPFAM	SSF64167. SurE-like_Pase/nucleotidase. 1 hit.
TIGRFAMs	TIGR00087. SurE. 1 hit.
ProtoNet	Search...

Entry information

Entry name

SURE_AGRRK

Accession

Primary (citable) accession number: B9JEH2

Entry history

Integrated into UniProtKB/Swiss-Prot:	July 28, 2009
Last sequence update:	March 24, 2009
Last modified:	January 25, 2012
This is version 21 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program