Skip Header

Contribute Send feedback
Read comments (?) or add your own

B9JE12 (B9JE12_AGRRK) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 17. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize order
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize order

Names and origin

Protein namesRecommended name:
ATP-dependent Clp protease proteolytic subunit 3 HAMAP MF_00444
EC=3.4.21.92 HAMAP MF_00444
Alternative name(s):
Endopeptidase Clp 3 HAMAP MF_00444
Gene names
Name:clpP EMBL ACM28358.1
Synonyms:clpP3 HAMAP MF_00444
Ordered Locus Names:Arad_4704
OrganismAgrobacterium radiobacter (strain K84 / ATCC BAA-868) [Complete proteome] [HAMAP]
Taxonomic identifier311403 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Rhizobiaceae › Rhizobium/Agrobacterium group › Agrobacterium

Protein attributes

Sequence length214 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins By similarity. HAMAP MF_00444

Catalytic activity

Hydrolysis of proteins to small peptides in the presence of ATP and magnesium. Alpha-casein is the usual test substrate. In the absence of ATP, only oligopeptides shorter than five residues are hydrolyzed (such as succinyl-Leu-Tyr-|-NHMec; and Leu-Tyr-Leu-|-Tyr-Trp, in which cleavage of the -Tyr-|-Leu- and -Tyr-|-Trp bonds also occurs). HAMAP MF_00444

Subcellular location

Cytoplasm By similarity HAMAP MF_00444.

Sequence similarities

Belongs to the peptidase S14 family. RuleBase RU003567 HAMAP MF_00444

Ontologies

Keywords
   Cellular componentCytoplasm HAMAP MF_00444
   LigandATP-binding HAMAP MF_00444
Nucleotide-binding
   Molecular functionHydrolase
Protease
Serine protease HAMAP MF_00444
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processproteolysis

Inferred from electronic annotation. Source: HAMAP

   Cellular componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular functionATP binding

Inferred from electronic annotation. Source: UniProtKB-KW

serine-type endopeptidase activity

Inferred from electronic annotation. Source: HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Active site1091 By similarity HAMAP MF_00444
Active site1341 By similarity HAMAP MF_00444

Sequences

Sequence LengthMass (Da)Tools
B9JE12 [UniParc].

Last modified March 24, 2009. Version 1.
Checksum: 4B53F80C494B1B18

FASTA21424,172
        10         20         30         40         50         60 
MEDWSSPMSE AMQLVPMVIE QSSRGERSFD IYSRLLRERI IFLNGEVNDT VSALVCAQLL 

        70         80         90        100        110        120 
FLEAENSRKP ISLYINSPGG VVTSGLAMYD TMRYIRAPVH TLCMGTARSM GSFLLMAGQA 

       130        140        150        160        170        180 
GERSALPNSS IHIHQPLGGF QGQASDMLIH AAEMERTKHR MTRLYAEHCG RTYEEFERAM 

       190        200        210 
DRDHFMTAEQ ALEWGLIDRI LQVREEDLPI APES

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000628 Genomic DNA. Translation: ACM28358.1.
RefSeqYP_002546291.1. NC_011985.1.

3D structure databases

ModBaseSearch...

Protein-protein interaction databases

STRINGB9JE12.

Protein family/group databases

MEROPSS14.001.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID7369594.
GenomeReviewsGene locus Arad_4704 in contig CP000628_GR.
KEGGara:Arad_4704.
PATRIC20808222. VBIAgrRad129173_6177.

Organism-specific databases

CMRSearch...

Phylogenomic databases

OMALYAEHCG.
ProtClustDBPRK00277.

Family and domain databases

HAMAPMF_00444. ClpP.
[Tree]
InterProIPR023562. Pept_S14/S49.
IPR001907. Pept_S14_ClpP.
[Graphical view]
KOK01358.
PANTHERPTHR10381. Pept_S14_ClpP. 1 hit.
PfamPF00574. CLP_protease. 1 hit.
[Graphical view]
PRINTSPR00127. CLPPROTEASEP.
ProtoNetSearch...

Entry information

Entry nameB9JE12_AGRRK
AccessionPrimary (citable) accession number: B9JE12
Entry history
Integrated into UniProtKB/TrEMBL: March 24, 2009
Last sequence update: March 24, 2009
Last modified: December 14, 2011
This is version 17 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info