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B9JBS3 (B9JBS3_AGRRK) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 21. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Hydroxyacylglutathione hydrolase HAMAP MF_01374
EC=3.1.2.6 HAMAP MF_01374
Alternative name(s):
Glyoxalase II HAMAP MF_01374
Gene names
Name:gloB HAMAP MF_01374 EMBL ACM27969.1
Ordered Locus Names:Arad_4219
OrganismAgrobacterium radiobacter (strain K84 / ATCC BAA-868) [Complete proteome] [HAMAP]
Taxonomic identifier311403 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Rhizobiaceae › Rhizobium/Agrobacterium group › Agrobacterium

Protein attributes

Sequence length256 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl-glutathione to form glutathione and D-lactic acid By similarity. HAMAP MF_01374 SAAS SAAS017782

Catalytic activity

S-(2-hydroxyacyl)glutathione + H2O = glutathione + a 2-hydroxy carboxylate. HAMAP MF_01374 SAAS SAAS017782

Cofactor

Binds 2 zinc ions per subunit By similarity. HAMAP MF_01374 SAAS SAAS017782

Pathway

Secondary metabolite metabolism; methylglyoxal degradation; (R)-lactate from methylglyoxal: step 2/2. HAMAP MF_01374

Subunit structure

Monomer By similarity. HAMAP MF_01374 SAAS SAAS017782

Sequence similarities

Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family. HAMAP MF_01374

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Metal binding571Zinc 1 By similarity HAMAP MF_01374
Metal binding591Zinc 1 By similarity HAMAP MF_01374
Metal binding611Zinc 2 By similarity HAMAP MF_01374
Metal binding621Zinc 2 By similarity HAMAP MF_01374
Metal binding1151Zinc 1 By similarity HAMAP MF_01374
Metal binding1341Zinc 1 By similarity HAMAP MF_01374
Metal binding1341Zinc 2 By similarity HAMAP MF_01374
Metal binding1721Zinc 2 By similarity HAMAP MF_01374

Sequences

Sequence LengthMass (Da)Tools
B9JBS3 [UniParc].

Last modified March 24, 2009. Version 1.
Checksum: 497EF1D6EAB7EC56

FASTA25628,458
        10         20         30         40         50         60 
MKPLELEVFL CRSDNFGVLV HDPETGYTAS IDAPEAGPIL AAAKRRGWTI THILTTHHHT 

        70         80         90        100        110        120 
DHVDANLALK EQFGCEIIGP IGEAVAIPGL DRAYGDGDSF EFGNHTVDVI ETPGHTAGHI 

       130        140        150        160        170        180 
CYHFVDDKLL FAADTLFALG CGRLFERPAM DMWASLQKLA VLPDETAIYF GHEYTLSNAR 

       190        200        210        220        230        240 
FALTIDPDNE RLKSRAADIE ALRAAGKFTI PTTLALEKET NPFLRAADPS IRRHLLMESR 

       250 
SNEEVFTEIR KRKDNF

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000628 Genomic DNA. Translation: ACM27969.1.
RefSeqYP_002545902.1. NC_011985.1.

3D structure databases

ModBaseSearch...

Protein-protein interaction databases

STRINGB9JBS3.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID7371118.
GenomeReviewsGene locus Arad_4219 in contig CP000628_GR.
KEGGara:Arad_4219.
PATRIC20807416. VBIAgrRad129173_5776.

Organism-specific databases

CMRSearch...

Phylogenomic databases

OMAFLCRTDN.
ProtClustDBCLSK800959.

Family and domain databases

HAMAPMF_01374. Glyoxalase_2.
[Tree]
InterProIPR001279. Beta-lactamas-like.
IPR017782. Hydroxyacylglutathione_Hdrlase.
[Graphical view]
KOK01069.
PANTHERPTHR11935:SF7. PTHR11935:SF7. 1 hit.
PfamPF00753. Lactamase_B. 1 hit.
[Graphical view]
SMARTSM00849. Lactamase_B. 1 hit.
[Graphical view]
TIGRFAMsTIGR03413. GSH_gloB. 1 hit.
ProtoNetSearch...

Entry information

Entry nameB9JBS3_AGRRK
AccessionPrimary (citable) accession number: B9JBS3
Entry history
Integrated into UniProtKB/TrEMBL: March 24, 2009
Last sequence update: March 24, 2009
Last modified: December 14, 2011
This is version 21 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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