Skip Header

Contribute Send feedback
Read comments (?) or add your own

B9JBA3 (BETB_AGRRK) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 23. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Betaine aldehyde dehydrogenase
Short name=BADH
EC=1.2.1.8
Gene names
Name:betB
Ordered Locus Names:Arad_1352
OrganismAgrobacterium radiobacter (strain K84 / ATCC BAA-868) [Complete proteome] [HAMAP]
Taxonomic identifier311403 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Rhizobiaceae › Rhizobium/Agrobacterium group › Agrobacterium

Protein attributes

Sequence length487 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

Betaine aldehyde + NAD+ + H2O = betaine + NADH. HAMAP MF_00804

Pathway

Amine and polyamine biosynthesis; betaine biosynthesis via choline pathway; betaine from betaine aldehyde: step 1/1. HAMAP MF_00804

Sequence similarities

Belongs to the aldehyde dehydrogenase family.

Ontologies

Keywords
   LigandNAD
   Molecular functionOxidoreductase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processbetaine biosynthetic process

Inferred from electronic annotation. Source: InterPro

   Molecular functionbetaine-aldehyde dehydrogenase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 487487Betaine aldehyde dehydrogenase HAMAP MF_00804
PRO_1000148553

Regions

Nucleotide binding228 – 2336NAD By similarity

Sites

Active site2501 By similarity
Active site2841 By similarity

Sequences

Sequence LengthMass (Da)Tools
B9JBA3 [UniParc].

Last modified March 24, 2009. Version 1.
Checksum: 5D1CE9618CF9FFF3

FASTA48751,753
        10         20         30         40         50         60 
MRAQPKASHF IDGEYVEDTD GTVIESIYPA TGEVIARLHA ATPAIVEQAI AAAKRAQPEW 

        70         80         90        100        110        120 
AAMSPTARGR ILKRAADIMR ERNRELSELE TLDTGKPIQE TIVADPTSGA DSFEFFGGIA 

       130        140        150        160        170        180 
AAGLNGSYIP LGGDFAYTKR VPLGVCVGIG AWNYPQQIAC WKGAPALVAG NAMVFKPSEN 

       190        200        210        220        230        240 
TPLGALKIAE ILIEAGLPKG LYNVIQGDRE TGPLLINHPD VAKVSLTGSV PTGRKVAAAA 

       250        260        270        280        290        300 
AGSLKHVTME LGGKSPLIVF DDADIDSAIG GAMLGNFYST GQVCSNGTRV FVNRKIKAEF 

       310        320        330        340        350        360 
LKRLKARTEA MLIGDPMDEA TQVGPMVSWA QREKVLSYIE KGKAEGATLV AGGGIPNNVS 

       370        380        390        400        410        420 
GEGYYVQPTV FADVTDDMTI AREEIFGPVM CVLDFDDEAE VIARANDTEF GLSGGVFTAD 

       430        440        450        460        470        480 
LTRAHRVVDQ LEAGTLWINA YNLAPVEIPF GGSKQSGFGR ENSLAALEHY SELKTVYVGM 


GPVQAPY

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000628 Genomic DNA. Translation: ACM25809.1.
RefSeqYP_002543735.1. NC_011985.1.

3D structure databases

ProteinModelPortalB9JBA3.
ModBaseSearch...

Protein-protein interaction databases

STRINGB9JBA3.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID7368367.
GenomeReviewsGene locus Arad_1352 in contig CP000628_GR.
KEGGara:Arad_1352.
PATRIC20802818. VBIAgrRad129173_3514.

Organism-specific databases

CMRSearch...

Phylogenomic databases

OMAIMRERNR.
ProtClustDBPRK13252.

Family and domain databases

HAMAPMF_00804. BADH.
[Tree]
InterProIPR016161. Ald_DH/histidinol_DH.
IPR016163. Ald_DH_C.
IPR016160. Ald_DH_CS.
IPR016162. Ald_DH_N.
IPR015590. Aldehyde_DH_dom.
IPR011264. Betaine_Ald_DH.
[Graphical view]
Gene3DG3DSA:3.40.309.10. Aldehyde_dehydrogenase_C. 1 hit.
G3DSA:3.40.605.10. Aldehyde_dehydrogenase_N. 1 hit.
KOK00130.
PfamPF00171. Aldedh. 1 hit.
[Graphical view]
SUPFAMSSF53720. Aldehyde_DH/Histidinol_DH. 1 hit.
TIGRFAMsTIGR01804. BADH. 1 hit.
PROSITEPS00070. ALDEHYDE_DEHYDR_CYS. 1 hit.
PS00687. ALDEHYDE_DEHYDR_GLU. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameBETB_AGRRK
AccessionPrimary (citable) accession number: B9JBA3
Entry history
Integrated into UniProtKB/Swiss-Prot: July 28, 2009
Last sequence update: March 24, 2009
Last modified: January 25, 2012
This is version 23 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·Documents