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B9JBA2 (BETA_AGRRK) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 26. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Choline dehydrogenase
Short name=CDH
Short name=CHD
EC=1.1.99.1
Gene names
Name:betA
Ordered Locus Names:Arad_1351
OrganismAgrobacterium radiobacter (strain K84 / ATCC BAA-868) [Complete proteome] [HAMAP]
Taxonomic identifier311403 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Rhizobiaceae › Rhizobium/Agrobacterium group › Agrobacterium

Protein attributes

Sequence length549 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Can catalyze the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine By similarity. HAMAP MF_00750

Catalytic activity

Choline + acceptor = betaine aldehyde + reduced acceptor. HAMAP MF_00750

Cofactor

FAD By similarity. HAMAP MF_00750

Pathway

Amine and polyamine biosynthesis; betaine biosynthesis via choline pathway; betaine aldehyde from choline (cytochrome c reductase route): step 1/1. HAMAP MF_00750

Sequence similarities

Belongs to the GMC oxidoreductase family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 549549Choline dehydrogenase HAMAP MF_00750
PRO_1000148349

Regions

Nucleotide binding4 – 3330FAD Potential

Sites

Active site4651 By similarity

Sequences

Sequence LengthMass (Da)Tools
B9JBA2 [UniParc].

Last modified March 24, 2009. Version 1.
Checksum: B16E4DA67444CB23

FASTA54960,921
        10         20         30         40         50         60 
MQADFVIIGS GSAGSAMASR LSEDGKHTVI VLEFGGSDVG PFIQMPAALA WPMSMDRYNW 

        70         80         90        100        110        120 
GYLSEPEPQL NNRRITAPRG KVIGGSSSIN GMVYVRGHAE DFNRWEELGA QGWAYADVLP 

       130        140        150        160        170        180 
YFKRMEHSHG GEEGWRGTDG PLHVRRGDAR NPLFHAFIEA GKQAGFEATE DYNGGKQEGF 

       190        200        210        220        230        240 
GLMEQTTWMG RRWSAATAYL KPALKRPNVE LIRCFARKVV IENGRATGVE IERGGKIEIV 

       250        260        270        280        290        300 
KANSEVIVSA SSFNSPKLLM LSGIGPGQHL QEMGIEVKID RPGVGANLQD HMEFYFQQTS 

       310        320        330        340        350        360 
LKPVSLYSWL PWYMQGIVGA QWMFFKSGLG TSNQFEACAF LRSAPGVKQP DIQYHFLPVA 

       370        380        390        400        410        420 
ISYDGKAAAK SHGFQAHVGY NLSKSRGAVT LRSSDPKADP VIRFNYMSHP EDWEKFRHCV 

       430        440        450        460        470        480 
RLTREIFGQK AFDDYRGPEI QPGPDVQTDD QIDAFLREHL ESAYHPCGTC KMGSKDDPMA 

       490        500        510        520        530        540 
VVDPDTRVIG VEGLRVADSS IFPSLTYGNL NGPSIMTGEK AADHILGKPR LARSNQEPWI 


NPRWEVSDR

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000628 Genomic DNA. Translation: ACM25808.1.
RefSeqYP_002543734.1. NC_011985.1.

3D structure databases

ModBaseSearch...

Protein-protein interaction databases

STRINGB9JBA2.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID7368366.
GenomeReviewsGene locus Arad_1351 in contig CP000628_GR.
KEGGara:Arad_1351.
PATRIC20802816. VBIAgrRad129173_3513.

Organism-specific databases

CMRSearch...

Phylogenomic databases

OMAGPFIQMP.
ProtClustDBPRK02106.

Family and domain databases

HAMAPMF_00750. Choline_dehydrogen.
[Tree]
InterProIPR011533. Choline_dehydrogenase.
IPR012132. GMC_OxRdtase.
IPR000172. GMC_OxRdtase_N.
IPR007867. GMC_OxRtase_C.
[Graphical view]
KOK00108.
PfamPF05199. GMC_oxred_C. 1 hit.
PF00732. GMC_oxred_N. 1 hit.
[Graphical view]
PIRSFPIRSF000137. Alcohol_oxidase. 1 hit.
TIGRFAMsTIGR01810. BetA. 1 hit.
PROSITEPS00623. GMC_OXRED_1. 1 hit.
PS00624. GMC_OXRED_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameBETA_AGRRK
AccessionPrimary (citable) accession number: B9JBA2
Entry history
Integrated into UniProtKB/Swiss-Prot: July 28, 2009
Last sequence update: March 24, 2009
Last modified: January 25, 2012
This is version 26 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

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