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B9JA15 (B9JA15_AGRRK) Unreviewed, UniProtKB/TrEMBL

Last modified June 11, 2014. Version 41. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Argininosuccinate synthase HAMAP-Rule MF_00005

EC=6.3.4.5 HAMAP-Rule MF_00005
Alternative name(s):
Citrulline--aspartate ligase HAMAP-Rule MF_00005
Gene names
Name:argG2 EMBL ACM25633.1
Synonyms:argG HAMAP-Rule MF_00005
Ordered Locus Names:Arad_1099 EMBL ACM25633.1
OrganismAgrobacterium radiobacter (strain K84 / ATCC BAA-868) [Complete proteome] [HAMAP] EMBL ACM25633.1
Taxonomic identifier311403 [NCBI]
Taxonomic lineageBacteriaProteobacteriaAlphaproteobacteriaRhizobialesRhizobiaceaeRhizobium/Agrobacterium groupAgrobacteriumAgrobacterium tumefaciens complex

Protein attributes

Sequence length407 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + L-citrulline + L-aspartate = AMP + diphosphate + N(omega)-(L-arginino)succinate. HAMAP-Rule MF_00005 SAAS SAAS001518

Pathway

Amino-acid biosynthesis; L-arginine biosynthesis; L-arginine from L-ornithine and carbamoyl phosphate: step 2/3. HAMAP-Rule MF_00005 SAAS SAAS001518

Subunit structure

Homotetramer By similarity. HAMAP-Rule MF_00005 SAAS SAAS001518

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00005 SAAS SAAS001518.

Sequence similarities

Belongs to the argininosuccinate synthase family. Type 1 subfamily. HAMAP-Rule MF_00005

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Regions

Nucleotide binding11 – 199ATP By similarity HAMAP-Rule MF_00005

Sites

Binding site381ATP; via amide nitrogen and carbonyl oxygen By similarity HAMAP-Rule MF_00005
Binding site891Citrulline By similarity HAMAP-Rule MF_00005
Binding site941Citrulline By similarity HAMAP-Rule MF_00005
Binding site1191ATP; via amide nitrogen By similarity HAMAP-Rule MF_00005
Binding site1211Aspartate By similarity HAMAP-Rule MF_00005
Binding site1251Aspartate By similarity HAMAP-Rule MF_00005
Binding site1251Citrulline By similarity HAMAP-Rule MF_00005
Binding site1261Aspartate By similarity HAMAP-Rule MF_00005
Binding site1291Citrulline By similarity HAMAP-Rule MF_00005
Binding site1801Citrulline By similarity HAMAP-Rule MF_00005
Binding site1891Citrulline By similarity HAMAP-Rule MF_00005
Binding site2651Citrulline By similarity HAMAP-Rule MF_00005
Binding site2771Citrulline By similarity HAMAP-Rule MF_00005

Sequences

Sequence LengthMass (Da)Tools
B9JA15 [UniParc].

Last modified March 24, 2009. Version 1.
Checksum: 281AA834D83E220A

FASTA40745,095
        10         20         30         40         50         60 
MIKDIKKIVL SYSGGLDTSI ILKWLQETYK CEVVTFTADL GQGEELEPAR AKAEMLAIKD 

        70         80         90        100        110        120 
IRIVDVREEF VRDFVFPMFR ANTVYEGQYL LGSSIARPLI AKHLVRIAQD VGADAISHGA 

       130        140        150        160        170        180 
TGKGNDQVRF ELTVNALDPS IKVIAPWREW NIQSRTQLID YAERNQIPVP TDKRGEAPFS 

       190        200        210        220        230        240 
IDANLLHTSS EGKVLEDPAD IAPDYVYQRT VDPVDAPNVP EIITIGFEKG DAVSLNGVKL 

       250        260        270        280        290        300 
SPATLLTRLN ELGGRHGVGR IDLVENRFVG MKSRGVYETP GGTILLAAHR GIESITLDRG 

       310        320        330        340        350        360 
AAHLKDEIMP RYAELIYNGF WYAPEREMLQ ALIDRSQTHV AGEVTVKLHK GSASVIARNS 

       370        380        390        400 
SNSLYSMDLV TFEEGSGSYD HHDAEGFIKL NGLRLKTLAA RNKRLGR 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000628 Genomic DNA. Translation: ACM25633.1.
RefSeqYP_002543558.1. NC_011985.1.

3D structure databases

ProteinModelPortalB9JA15.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING311403.Arad_1099.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaACM25633; ACM25633; Arad_1099.
GeneID7369470.
KEGGara:Arad_1099.
PATRIC20802442. VBIAgrRad129173_3328.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0137.
HOGENOMHOG000230093.
KOK01940.
OMAYAPEREM.
OrthoDBEOG6K9QCV.

Enzyme and pathway databases

BioCycARAD311403:GHU8-858-MONOMER.
UniPathwayUPA00068; UER00113.

Family and domain databases

Gene3D3.40.50.620. 1 hit.
3.90.1260.10. 1 hit.
HAMAPMF_00005. Arg_succ_synth_type1.
InterProIPR001518. Arginosuc_synth.
IPR018223. Arginosuc_synth_CS.
IPR023434. Arginosuc_synth_type_1_subfam.
IPR024074. AS_cat/multimer_dom_body.
IPR014729. Rossmann-like_a/b/a_fold.
[Graphical view]
PfamPF00764. Arginosuc_synth. 1 hit.
[Graphical view]
TIGRFAMsTIGR00032. argG. 1 hit.
PROSITEPS00564. ARGININOSUCCIN_SYN_1. 1 hit.
PS00565. ARGININOSUCCIN_SYN_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameB9JA15_AGRRK
AccessionPrimary (citable) accession number: B9JA15
Entry history
Integrated into UniProtKB/TrEMBL: March 24, 2009
Last sequence update: March 24, 2009
Last modified: June 11, 2014
This is version 41 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)