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B9J6S5 (PNCB_AGRRK) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 41. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Nicotinate phosphoribosyltransferase

Short name=NAPRTase
EC=6.3.4.21
Gene names
Name:pncB
Ordered Locus Names:Arad_0309
OrganismAgrobacterium radiobacter (strain K84 / ATCC BAA-868) [Complete proteome] [HAMAP]
Taxonomic identifier311403 [NCBI]
Taxonomic lineageBacteriaProteobacteriaAlphaproteobacteriaRhizobialesRhizobiaceaeRhizobium/Agrobacterium groupAgrobacteriumAgrobacterium tumefaciens complex

Protein attributes

Sequence length434 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP By similarity. HAMAP-Rule MF_00570

Catalytic activity

Nicotinate + 5-phospho-alpha-D-ribose 1-diphosphate + ATP + H2O = beta-nicotinate D-ribonucleotide + diphosphate + ADP + phosphate. HAMAP-Rule MF_00570

Pathway

Cofactor biosynthesis; NAD(+) biosynthesis; nicotinate D-ribonucleotide from nicotinate: step 1/1. HAMAP-Rule MF_00570

Sequence similarities

Belongs to the NAPRTase family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 434434Nicotinate phosphoribosyltransferase HAMAP-Rule MF_00570
PRO_1000146826

Sequences

Sequence LengthMass (Da)Tools
B9J6S5 [UniParc].

Last modified March 24, 2009. Version 1.
Checksum: 384AF5A7A623A179

FASTA43449,611
        10         20         30         40         50         60 
MTKTDIAARV YNHTWKLDPI VRSLIDTDFY KLLMLQMIWK LYPDVDATFS LINRTKSVRL 

        70         80         90        100        110        120 
AEVIDEKELR EQLDHARTLR LSKKEMIWLA GNSFYGRAQI FEPEFLTWLS NFQLPDYELS 

       130        140        150        160        170        180 
KRDGQYVLDF HGSWKETTMW EIPALAIINE LRSRTALKAL GPFTLDVLYA RAKAKMWEKV 

       190        200        210        220        230        240 
ERLRELPDLH ISDFGTRRRH SFLWQRWCVE ALKEGVPHAF TGTSNVLLAM DSDLEAVGTN 

       250        260        270        280        290        300 
AHELPMVAAA LAKTDEELGK APYKVLRDWN RLYGGNLLVV LPDAFGTASF LRNAPEWVAD 

       310        320        330        340        350        360 
WTGFRPDSAP PIEGGEKIID WWKKMGRDPR QKLLIFSDGL DVDAIIATYK HFEGRVRMGF 

       370        380        390        400        410        420 
GWGTNLTNDF AGCAPTEIHG LNPISIVCKV IEANGRPAVK LSDNPQKATG EPAEVERYLK 

       430 
FFGAEDRVDH EVLV 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000628 Genomic DNA. Translation: ACM25031.1.
RefSeqYP_002542956.1. NC_011985.1.

3D structure databases

ProteinModelPortalB9J6S5.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING311403.Arad_0309.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaACM25031; ACM25031; Arad_0309.
GeneID7369682.
KEGGara:Arad_0309.
PATRIC20801159. VBIAgrRad129173_2693.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG1488.
HOGENOMHOG000284929.
KOK00763.
OMASIVCKVI.
OrthoDBEOG6X10XB.

Enzyme and pathway databases

BioCycARAD311403:GHU8-248-MONOMER.
UniPathwayUPA00253; UER00457.

Family and domain databases

HAMAPMF_00570. NAPRTase.
InterProIPR006406. Nic_PRibTrfase.
IPR007229. Nic_PRibTrfase-Fam.
IPR002638. Quinolinate_PRibosylTrfase_C.
[Graphical view]
PANTHERPTHR11098:SF1. PTHR11098:SF1. 1 hit.
PfamPF04095. NAPRTase. 1 hit.
[Graphical view]
PIRSFPIRSF000484. NAPRT. 1 hit.
SUPFAMSSF51690. SSF51690. 1 hit.
TIGRFAMsTIGR01514. NAPRTase. 1 hit.
ProtoNetSearch...

Entry information

Entry namePNCB_AGRRK
AccessionPrimary (citable) accession number: B9J6S5
Entry history
Integrated into UniProtKB/Swiss-Prot: July 28, 2009
Last sequence update: March 24, 2009
Last modified: May 14, 2014
This is version 41 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways