ID   B9IZB4_BACCQ            Unreviewed;       310 AA.
AC   B9IZB4;
DT   24-MAR-2009, integrated into UniProtKB/TrEMBL.
DT   24-MAR-2009, sequence version 1.
DT   27-MAR-2024, entry version 67.
DE   RecName: Full=DNA-directed DNA polymerase {ECO:0000256|ARBA:ARBA00012417};
DE            EC=2.7.7.7 {ECO:0000256|ARBA:ARBA00012417};
GN   Name=holB {ECO:0000313|EMBL:ACM10558.1};
GN   OrderedLocusNames=BCQ_0038 {ECO:0000313|EMBL:ACM10558.1};
OS   Bacillus cereus (strain Q1).
OC   Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae; Bacillus;
OC   Bacillus cereus group.
OX   NCBI_TaxID=361100 {ECO:0000313|EMBL:ACM10558.1, ECO:0000313|Proteomes:UP000000441};
RN   [1] {ECO:0000313|EMBL:ACM10558.1, ECO:0000313|Proteomes:UP000000441}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Q1 {ECO:0000313|EMBL:ACM10558.1,
RC   ECO:0000313|Proteomes:UP000000441};
RX   PubMed=19060151; DOI=10.1128/JB.01629-08;
RA   Xiong Z., Jiang Y., Qi D., Lu H., Yang F., Yang J., Chen L., Sun L., Xu X.,
RA   Xue Y., Zhu Y., Jin Q.;
RT   "Complete genome sequence of the extremophilic Bacillus cereus strain Q1
RT   with industrial applications.";
RL   J. Bacteriol. 191:1120-1121(2009).
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) =
CC         diphosphate + DNA(n+1); Xref=Rhea:RHEA:22508, Rhea:RHEA-COMP:17339,
CC         Rhea:RHEA-COMP:17340, ChEBI:CHEBI:33019, ChEBI:CHEBI:61560,
CC         ChEBI:CHEBI:173112; EC=2.7.7.7;
CC         Evidence={ECO:0000256|ARBA:ARBA00024632};
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; CP000227; ACM10558.1; -; Genomic_DNA.
DR   AlphaFoldDB; B9IZB4; -.
DR   KEGG; bcq:BCQ_0038; -.
DR   HOGENOM; CLU_006229_4_5_9; -.
DR   Proteomes; UP000000441; Chromosome.
DR   GO; GO:0008408; F:3'-5' exonuclease activity; IEA:InterPro.
DR   GO; GO:0003887; F:DNA-directed DNA polymerase activity; IEA:UniProtKB-KW.
DR   GO; GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR   InterPro; IPR004622; DNA_pol_HolB.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   NCBIfam; TIGR00678; holB; 1.
DR   PANTHER; PTHR11669:SF8; DNA POLYMERASE III SUBUNIT DELTA; 1.
DR   PANTHER; PTHR11669; REPLICATION FACTOR C / DNA POLYMERASE III GAMMA-TAU SUBUNIT; 1.
DR   Pfam; PF13177; DNA_pol3_delta2; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE   4: Predicted;
KW   DNA replication {ECO:0000256|ARBA:ARBA00022705};
KW   DNA-directed DNA polymerase {ECO:0000256|ARBA:ARBA00022932};
KW   Nucleotidyltransferase {ECO:0000256|ARBA:ARBA00022695};
KW   Transferase {ECO:0000256|ARBA:ARBA00022679}.
SQ   SEQUENCE   310 AA;  35140 MW;  92B24214A0F3BCBB CRC64;
     MLMNSIAKER ISHAYLLEGG KGTGKFATAI QMAKSFLCSQ RNGVEPCHVC TNCKRIDSGN
     HPNLHIVKPD GLSIKKQQIH DLQEEFSKTG LEANKKVYVI EHADRMTANA ANTLLKFLEE
     PSSDTTAILL TEQSHQILNT ILSRCQVVTF RPLPTESLIR RLQDEGITAS LSTLAAQLTN
     SFDEALALCS DEWFAQARAL VIKLCEALEK DKASIFFVQE KWGKHFREKE QLQQGLDMLL
     LIYKDLLYVQ LGEEDRLVFH EQKEMFESFS YAQKRIVSAL FNILEAKNRI NANVNAQLVF
     EQLVLRLQEG
//