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B9GH07

- B9GH07_POPTR

UniProt

B9GH07 - B9GH07_POPTR

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Protein
Histidinol dehydrogenase, chloroplastic
Gene
POPTR_0001s46960g
Organism
Populus trichocarpa (Western balsam poplar) (Populus balsamifera subsp. trichocarpa)
Status
Unreviewed - Annotation score: 3 out of 5 - Protein inferred from homologyi

Functioni

Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine By similarity.UniRule annotation

Catalytic activityi

L-histidinol + H2O + 2 NAD+ = L-histidine + 2 NADH.UniRule annotation

Cofactori

Binds 1 zinc ion per subunit By similarity.UniRule annotation

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei127 – 1271NAD By similarityUniRule annotation
Binding sitei189 – 1891NAD By similarityUniRule annotation
Binding sitei212 – 2121NAD By similarityUniRule annotation
Binding sitei238 – 2381Substrate By similarityUniRule annotation
Metal bindingi260 – 2601Zinc By similarityUniRule annotation
Binding sitei260 – 2601Substrate By similarityUniRule annotation
Metal bindingi263 – 2631Zinc By similarityUniRule annotation
Binding sitei263 – 2631Substrate By similarityUniRule annotation
Active sitei328 – 3281Proton acceptor By similarity
Active sitei329 – 3291Proton acceptor By similarityUniRule annotation
Binding sitei329 – 3291Substrate By similarityUniRule annotation
Metal bindingi362 – 3621Zinc By similarityUniRule annotation
Binding sitei362 – 3621Substrate By similarityUniRule annotation
Binding sitei416 – 4161Substrate By similarityUniRule annotation
Metal bindingi421 – 4211Zinc By similarityUniRule annotation
Binding sitei421 – 4211Substrate By similarityUniRule annotation

GO - Molecular functioni

  1. NAD binding Source: InterPro
  2. histidinol dehydrogenase activity Source: UniProtKB-EC
  3. zinc ion binding Source: InterPro

GO - Biological processi

  1. histidine biosynthetic process Source: UniProtKB-UniPathway
Complete GO annotation...

Keywords - Molecular functioni

OxidoreductaseUniRule annotation

Keywords - Biological processi

Amino-acid biosynthesis, Histidine biosynthesisUniRule annotation

Keywords - Ligandi

Metal-bindingUniRule annotation, NADUniRule annotation, ZincUniRule annotation

Enzyme and pathway databases

UniPathwayiUPA00031; UER00014.

Names & Taxonomyi

Protein namesi
Recommended name:
Histidinol dehydrogenase, chloroplasticUniRule annotation (EC:1.1.1.23UniRule annotation)
Short name:
HDHUniRule annotation
Gene namesi
ORF Names:POPTR_0001s46960gImported
OrganismiPopulus trichocarpa (Western balsam poplar) (Populus balsamifera subsp. trichocarpa)Imported
Taxonomic identifieri3694 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsfabidsMalpighialesSalicaceaeSaliceaePopulus
ProteomesiUP000006729: Unassembled WGS sequence

Subcellular locationi

Plastidchloroplast By similarity UniRule annotation

GO - Cellular componenti

  1. chloroplast Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

ChloroplastUniRule annotation, Plastid

Interactioni

Protein-protein interaction databases

STRINGi3694.eugene3.00013048.

Structurei

3D structure databases

ProteinModelPortaliB9GH07.

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG0141.
HOGENOMiHOG000243914.
KOiK00013.
OMAiFQEITRE.

Family and domain databases

HAMAPiMF_01024. HisD.
InterProiIPR016161. Ald_DH/histidinol_DH.
IPR001692. Histidinol_DH_CS.
IPR022695. Histidinol_DH_monofunct.
IPR012131. Hstdl_DH.
[Graphical view]
PfamiPF00815. Histidinol_dh. 1 hit.
[Graphical view]
PIRSFiPIRSF000099. Histidinol_dh. 1 hit.
PRINTSiPR00083. HOLDHDRGNASE.
SUPFAMiSSF53720. SSF53720. 1 hit.
TIGRFAMsiTIGR00069. hisD. 1 hit.
PROSITEiPS00611. HISOL_DEHYDROGENASE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

B9GH07-1 [UniParc]FASTAAdd to Basket

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MCAMKSYRLS ELNNSEVESL KARPRIDFSS IFGIVNPIVD DVRQRGDAAV    50
KDYTSRFDKV KLDKIVENVS ELPDPELDAT VKEAFDVAYN NIYAFHLAQK 100
SVEKSVETMK GVRCKRVARS ISSVGLYVPG GTAVLPSTAL MLAIPAQIAG 150
CKTVVLATPP AQDGSICKEV LYCAKKAGVT HILKAGGAQA ISAMAWGTES 200
CPKAEKIFGP GNQYVTAAKM ILQNSEAMIS IDMPAGPSEV LVIADRYASP 250
VHIAADLLSQ AEHGPDSQVV LVVAGDGVDM KAIEEEISKQ CQSLPRGEYA 300
SKALSHSFTV FARDMVEAVS FSNLYAPEHL IINVKEAEKW ESFIENAGSV 350
FLGPWTPESV GDYASGTNHV LPTYGYARMY GGVSLDSFQK YMTVQSLTEE 400
GLRKLGPYVA TMAEVEGLDA HKRAVTLRLQ DIEARQVSNT R 441
Length:441
Mass (Da):47,768
Last modified:March 24, 2009 - v1
Checksum:iE10AFE0C50A7EAF6
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CM000337 Genomic DNA. Translation: EEE85368.1.
RefSeqiXP_002300563.1. XM_002300527.2.

Genome annotation databases

EnsemblPlantsiPOPTR_0001s46960.1; POPTR_0001s46960.1; POPTR_0001s46960.
GeneIDi7480422.
KEGGipop:POPTR_0001s46960g.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CM000337 Genomic DNA. Translation: EEE85368.1 .
RefSeqi XP_002300563.1. XM_002300527.2.

3D structure databases

ProteinModelPortali B9GH07.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 3694.eugene3.00013048.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblPlantsi POPTR_0001s46960.1 ; POPTR_0001s46960.1 ; POPTR_0001s46960 .
GeneIDi 7480422.
KEGGi pop:POPTR_0001s46960g.

Phylogenomic databases

eggNOGi COG0141.
HOGENOMi HOG000243914.
KOi K00013.
OMAi FQEITRE.

Enzyme and pathway databases

UniPathwayi UPA00031 ; UER00014 .

Family and domain databases

HAMAPi MF_01024. HisD.
InterProi IPR016161. Ald_DH/histidinol_DH.
IPR001692. Histidinol_DH_CS.
IPR022695. Histidinol_DH_monofunct.
IPR012131. Hstdl_DH.
[Graphical view ]
Pfami PF00815. Histidinol_dh. 1 hit.
[Graphical view ]
PIRSFi PIRSF000099. Histidinol_dh. 1 hit.
PRINTSi PR00083. HOLDHDRGNASE.
SUPFAMi SSF53720. SSF53720. 1 hit.
TIGRFAMsi TIGR00069. hisD. 1 hit.
PROSITEi PS00611. HISOL_DEHYDROGENASE. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "The genome of black cottonwood, Populus trichocarpa (Torr. & Gray)."
    Tuskan G.A., Difazio S., Jansson S., Bohlmann J., Grigoriev I., Hellsten U., Putnam N., Ralph S., Rombauts S., Salamov A., Schein J., Sterck L., Aerts A., Bhalerao R.R., Bhalerao R.P., Blaudez D., Boerjan W., Brun A.
    , Brunner A., Busov V., Campbell M., Carlson J., Chalot M., Chapman J., Chen G.-L., Cooper D., Coutinho P.M., Couturier J., Covert S., Cronk Q., Cunningham R., Davis J., Degroeve S., Dejardin A., dePamphilis C.W., Detter J., Dirks B., Dubchak I., Duplessis S., Ehlting J., Ellis B., Gendler K., Goodstein D., Gribskov M., Grimwood J., Groover A., Gunter L., Hamberger B., Heinze B., Helariutta Y., Henrissat B., Holligan D., Holt R., Huang W., Islam-Faridi N., Jones S., Jones-Rhoades M., Jorgensen R., Joshi C., Kangasjaervi J., Karlsson J., Kelleher C., Kirkpatrick R., Kirst M., Kohler A., Kalluri U., Larimer F., Leebens-Mack J., Leple J.-C., Locascio P., Lou Y., Lucas S., Martin F., Montanini B., Napoli C., Nelson D.R., Nelson C., Nieminen K., Nilsson O., Pereda V., Peter G., Philippe R., Pilate G., Poliakov A., Razumovskaya J., Richardson P., Rinaldi C., Ritland K., Rouze P., Ryaboy D., Schmutz J., Schrader J., Segerman B., Shin H., Siddiqui A., Sterky F., Terry A., Tsai C.-J., Uberbacher E., Unneberg P., Vahala J., Wall K., Wessler S., Yang G., Yin T., Douglas C., Marra M., Sandberg G., Van de Peer Y., Rokhsar D.S.
    Science 313:1596-1604(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: cv. Nisqually.

Entry informationi

Entry nameiB9GH07_POPTR
AccessioniPrimary (citable) accession number: B9GH07
Entry historyi
Integrated into UniProtKB/TrEMBL: March 24, 2009
Last sequence update: March 24, 2009
Last modified: September 3, 2014
This is version 48 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

External Data

Dasty 3

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