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B9EJX5

- B9EJX5_MOUSE

UniProt

B9EJX5 - B9EJX5_MOUSE

Protein
Submitted name:

TAF2 RNA polymerase II, TATA box binding protein (TBP)-associated factor

Gene

Taf2

Organism
Mus musculus (Mouse)
Status
Unreviewed - Annotation score: 2 out of 5- Experimental evidence at transcript leveli
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    • History
      Entry version 37 (01 Oct 2014)
      Sequence version 1 (24 Mar 2009)
      Previous versions | rss
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    Functioni

    GO - Molecular functioni

    1. metallopeptidase activity Source: InterPro
    2. transcription regulatory region DNA binding Source: Ensembl
    3. zinc ion binding Source: InterPro

    GO - Biological processi

    1. G2/M transition of mitotic cell cycle Source: Ensembl
    2. positive regulation of transcription from RNA polymerase II promoter Source: Ensembl
    3. response to organic cyclic compound Source: Ensembl
    4. transcription initiation from RNA polymerase II promoter Source: Ensembl

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    TAF2 RNA polymerase II, TATA box binding protein (TBP)-associated factorImported
    Submitted name:
    Transcription initiation factor TFIID subunit 2Imported
    Gene namesi
    Name:Taf2Imported
    OrganismiMus musculus (Mouse)Imported
    Taxonomic identifieri10090 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
    ProteomesiUP000000589: Chromosome 15

    Organism-specific databases

    MGIiMGI:2443028. Taf2.

    Subcellular locationi

    GO - Cellular componenti

    1. transcription factor TFIID complex Source: MGI
    2. transcription factor TFTC complex Source: Ensembl

    Expressioni

    Gene expression databases

    GenevestigatoriB9EJX5.

    Family & Domainsi

    Phylogenomic databases

    GeneTreeiENSGT00390000000420.
    HOGENOMiHOG000046103.
    HOVERGENiHBG094022.
    KOiK03128.
    OMAiCHSESKQ.
    OrthoDBiEOG7R2BHS.
    TreeFamiTF315208.

    Family and domain databases

    InterProiIPR016024. ARM-type_fold.
    IPR014782. Peptidase_M1_N.
    [Graphical view]
    PfamiPF01433. Peptidase_M1. 1 hit.
    [Graphical view]
    SUPFAMiSSF48371. SSF48371. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    B9EJX5-1 [UniParc]FASTAAdd to Basket

    « Hide

    MPPTGLESSR MNRKKGDKGF ESPRPYKLTH QVVCINNINF QRKSVVGFVE     50
    LTIFPTVANL NRIKLNSKQC RIYRVRINDL EAAFIYNDPT LEVCHSESKQ 100
    RNLNYFSNAY AAAVSAVDPD AGNGELCIKV PSELWKHVDE LKVLKIHINF 150
    SLDQPKGGLH FVVPSVEGSM AERGAHVFSC GYQNSTRFWF PCVDSYSELC 200
    TWKLEFTVDA AMVAVSNGDL VETVYTHDMR KKTFHYMLTI PTAASNISLA 250
    IGPFEILVDP YMHEVTHFCL PQLLPLLKHT TSYIHEVFEF YEEILTCRYP 300
    YSCFKTVFID EAYVEVAAYA SMSIFSTNLL HSAMIIDETP LTRRCLAQAL 350
    AQQFFGCFIS RMSWSDEWVL KGISGYIYGL WMKKTFGVNE YHHWIKEELD 400
    KIVAYELKTG GVLLHPIFGG GKEKDNPASH LHFSIKHPHT LSWEYYTMFQ 450
    CKAHLVMRLI ENRISMEFML QVFNKLLSLA STASSQKFQS HMWSQMLVST 500
    YGFLKSISNV SGKDIQPLIK QWVDQSGVVK FYGSFAFNRK RNVLELEIKQ 550
    DYTSPGTQKY VGPLKVTVQE LDGSFNHTLQ IEENSLKHDI PCHSKSRRNK 600
    KKKIPLMNGE EVDMDLSAMD ADSPLLWIRI DPDMSVLRKV EFEQADFMWQ 650
    YELRYERDVV AQQESILALE KFPTPASRLA LTDILEQEQC FYRVRMSACF 700
    CLAKIANSMV STWTGPPAMK SLFTRMFCCK TCPNIVKTNN FMSFQSYFLQ 750
    KTMPVAMALL RDVHNLCPKE VLTFILDLIK YNDNRKNKFS DNYYRAEMID 800
    ALANSVTPAV SVNNEVRTLD NLNPDVRLIL EEITRFLNME KLLPSYRHTI 850
    TVSCLRAIRV LQKNGHVPSD ASLFKSYAEY GHFVDIRIAA LEAVVDYTKV 900
    DRSYEELQWL LNMIQTDPVP YVRHKILNML TKNPPFTKNM ESPLCNEALV 950
    DQLWKLMNSG TAHDWRLRCG AVDLYFTLFG LSRPSCLPLP ELGLVLNLKE 1000
    KKAVLNPTII PEAGVGNQES ASNPGCHAQL AGFQNPFSSS QDEEEVDMDT 1050
    VHDSQAFISH HLNMLERPST PGLSKYRPSG SRSSLMPQHS LGCDITPPTK 1100
    PQWSMELSRK GAGKEQPLEM GVHSMVAAPL SMFAKEALSS RHSEHHHHHH 1150
    HEHKKKKKKH KHKHKHKHKH DSKDKDREPF AFSSPASGRS VRSPSLSD 1198
    Length:1,198
    Mass (Da):136,926
    Last modified:March 24, 2009 - v1
    Checksum:i9FA604069E20829C
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AC137950 Genomic DNA. No translation available.
    BC147638 mRNA. Translation: AAI47639.1.
    BC151079 mRNA. Translation: AAI51080.1.
    RefSeqiNP_001074757.1. NM_001081288.1.
    UniGeneiMm.380957.

    Genome annotation databases

    EnsembliENSMUST00000041733; ENSMUSP00000043733; ENSMUSG00000037343.
    GeneIDi319944.
    KEGGimmu:319944.
    UCSCiuc007vrt.1. mouse.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AC137950 Genomic DNA. No translation available.
    BC147638 mRNA. Translation: AAI47639.1 .
    BC151079 mRNA. Translation: AAI51080.1 .
    RefSeqi NP_001074757.1. NM_001081288.1.
    UniGenei Mm.380957.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENSMUST00000041733 ; ENSMUSP00000043733 ; ENSMUSG00000037343 .
    GeneIDi 319944.
    KEGGi mmu:319944.
    UCSCi uc007vrt.1. mouse.

    Organism-specific databases

    CTDi 6873.
    MGIi MGI:2443028. Taf2.

    Phylogenomic databases

    GeneTreei ENSGT00390000000420.
    HOGENOMi HOG000046103.
    HOVERGENi HBG094022.
    KOi K03128.
    OMAi CHSESKQ.
    OrthoDBi EOG7R2BHS.
    TreeFami TF315208.

    Miscellaneous databases

    ChiTaRSi TAF2. mouse.
    NextBioi 395709.
    SOURCEi Search...

    Gene expression databases

    Genevestigatori B9EJX5.

    Family and domain databases

    InterProi IPR016024. ARM-type_fold.
    IPR014782. Peptidase_M1_N.
    [Graphical view ]
    Pfami PF01433. Peptidase_M1. 1 hit.
    [Graphical view ]
    SUPFAMi SSF48371. SSF48371. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Gerhard D.S., Wagner L., Feingold E.A., Shenmen C.M., Grouse L.H., Schuler G., Klein S.L., Old S., Rasooly R., Good P., Guyer M., Peck A.M., Derge J.G., Lipman D., Collins F.S., Jang W., Sherry S., Feolo M.
      , Misquitta L., Lee E., Rotmistrovsky K., Greenhut S.F., Schaefer C.F., Buetow K., Bonner T.I., Haussler D., Kent J., Kiekhaus M., Furey T., Brent M., Prange C., Schreiber K., Shapiro N., Bhat N.K., Hopkins R.F., Hsie F., Driscoll T., Soares M.B., Casavant T.L., Scheetz T.E., Brown-stein M.J., Usdin T.B., Toshiyuki S., Carninci P., Piao Y., Dudekula D.B., Ko M.S., Kawakami K., Suzuki Y., Sugano S., Gruber C.E., Smith M.R., Simmons B., Moore T., Waterman R., Johnson S.L., Ruan Y., Wei C.L., Mathavan S., Gunaratne P.H., Wu J., Garcia A.M., Hulyk S.W., Fuh E., Yuan Y., Sneed A., Kowis C., Hodgson A., Muzny D.M., McPherson J., Gibbs R.A., Fahey J., Helton E., Ketteman M., Madan A., Rodrigues S., Sanchez A., Whiting M., Madari A., Young A.C., Wetherby K.D., Granite S.J., Kwong P.N., Brinkley C.P., Pearson R.L., Bouffard G.G., Blakesly R.W., Green E.D., Dickson M.C., Rodriguez A.C., Grimwood J., Schmutz J., Myers R.M., Butterfield Y.S., Griffith M., Griffith O.L., Krzywinski M.I., Liao N., Morin R., Morrin R., Palmquist D., Petrescu A.S., Skalska U., Smailus D.E., Stott J.M., Schnerch A., Schein J.E., Jones S.J., Holt R.A., Baross A., Marra M.A., Clifton S., Makowski K.A., Bosak S., Malek J.
      Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
      Tissue: BrainImported and TesticleImported.
    2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: C57BL/6JImported.
    3. Ensembl
      Submitted (FEB-2012) to UniProtKB
      Cited for: IDENTIFICATION.
      Strain: C57BL/6JImported.

    Entry informationi

    Entry nameiB9EJX5_MOUSE
    AccessioniPrimary (citable) accession number: B9EJX5
    Entry historyi
    Integrated into UniProtKB/TrEMBL: March 24, 2009
    Last sequence update: March 24, 2009
    Last modified: October 1, 2014
    This is version 37 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3