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B9EJX5

- B9EJX5_MOUSE

UniProt

B9EJX5 - B9EJX5_MOUSE

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Protein
Submitted name:

TAF2 RNA polymerase II, TATA box binding protein (TBP)-associated factor

Gene

Taf2

Organism
Mus musculus (Mouse)
Status
Unreviewed - Annotation score: 2 out of 5- Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  1. metallopeptidase activity Source: InterPro
  2. transcription regulatory region DNA binding Source: Ensembl
  3. zinc ion binding Source: InterPro

GO - Biological processi

  1. G2/M transition of mitotic cell cycle Source: Ensembl
  2. positive regulation of transcription from RNA polymerase II promoter Source: Ensembl
  3. response to organic cyclic compound Source: Ensembl
  4. transcription initiation from RNA polymerase II promoter Source: Ensembl
Complete GO annotation...

Enzyme and pathway databases

ReactomeiREACT_230204. RNA Polymerase II Transcription Initiation And Promoter Clearance.
REACT_232708. RNA Polymerase II Transcription Pre-Initiation And Promoter Opening.
REACT_244380. RNA Polymerase II Transcription Initiation.
REACT_255009. RNA Polymerase II Pre-transcription Events.
REACT_255334. RNA Polymerase II Promoter Escape.

Names & Taxonomyi

Protein namesi
Submitted name:
TAF2 RNA polymerase II, TATA box binding protein (TBP)-associated factorImported
Submitted name:
Transcription initiation factor TFIID subunit 2Imported
Gene namesi
Name:Taf2Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
ProteomesiUP000000589: Chromosome 15

Organism-specific databases

MGIiMGI:2443028. Taf2.

Subcellular locationi

GO - Cellular componenti

  1. transcription factor TFIID complex Source: MGI
  2. transcription factor TFTC complex Source: Ensembl
Complete GO annotation...

Expressioni

Gene expression databases

GenevestigatoriB9EJX5.

Family & Domainsi

Phylogenomic databases

GeneTreeiENSGT00390000000420.
HOGENOMiHOG000046103.
HOVERGENiHBG094022.
KOiK03128.
OMAiCHSESKQ.
OrthoDBiEOG7R2BHS.
TreeFamiTF315208.

Family and domain databases

InterProiIPR016024. ARM-type_fold.
IPR014782. Peptidase_M1_N.
[Graphical view]
PfamiPF01433. Peptidase_M1. 1 hit.
[Graphical view]
SUPFAMiSSF48371. SSF48371. 1 hit.

Sequencei

Sequence statusi: Complete.

B9EJX5-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MPPTGLESSR MNRKKGDKGF ESPRPYKLTH QVVCINNINF QRKSVVGFVE
60 70 80 90 100
LTIFPTVANL NRIKLNSKQC RIYRVRINDL EAAFIYNDPT LEVCHSESKQ
110 120 130 140 150
RNLNYFSNAY AAAVSAVDPD AGNGELCIKV PSELWKHVDE LKVLKIHINF
160 170 180 190 200
SLDQPKGGLH FVVPSVEGSM AERGAHVFSC GYQNSTRFWF PCVDSYSELC
210 220 230 240 250
TWKLEFTVDA AMVAVSNGDL VETVYTHDMR KKTFHYMLTI PTAASNISLA
260 270 280 290 300
IGPFEILVDP YMHEVTHFCL PQLLPLLKHT TSYIHEVFEF YEEILTCRYP
310 320 330 340 350
YSCFKTVFID EAYVEVAAYA SMSIFSTNLL HSAMIIDETP LTRRCLAQAL
360 370 380 390 400
AQQFFGCFIS RMSWSDEWVL KGISGYIYGL WMKKTFGVNE YHHWIKEELD
410 420 430 440 450
KIVAYELKTG GVLLHPIFGG GKEKDNPASH LHFSIKHPHT LSWEYYTMFQ
460 470 480 490 500
CKAHLVMRLI ENRISMEFML QVFNKLLSLA STASSQKFQS HMWSQMLVST
510 520 530 540 550
YGFLKSISNV SGKDIQPLIK QWVDQSGVVK FYGSFAFNRK RNVLELEIKQ
560 570 580 590 600
DYTSPGTQKY VGPLKVTVQE LDGSFNHTLQ IEENSLKHDI PCHSKSRRNK
610 620 630 640 650
KKKIPLMNGE EVDMDLSAMD ADSPLLWIRI DPDMSVLRKV EFEQADFMWQ
660 670 680 690 700
YELRYERDVV AQQESILALE KFPTPASRLA LTDILEQEQC FYRVRMSACF
710 720 730 740 750
CLAKIANSMV STWTGPPAMK SLFTRMFCCK TCPNIVKTNN FMSFQSYFLQ
760 770 780 790 800
KTMPVAMALL RDVHNLCPKE VLTFILDLIK YNDNRKNKFS DNYYRAEMID
810 820 830 840 850
ALANSVTPAV SVNNEVRTLD NLNPDVRLIL EEITRFLNME KLLPSYRHTI
860 870 880 890 900
TVSCLRAIRV LQKNGHVPSD ASLFKSYAEY GHFVDIRIAA LEAVVDYTKV
910 920 930 940 950
DRSYEELQWL LNMIQTDPVP YVRHKILNML TKNPPFTKNM ESPLCNEALV
960 970 980 990 1000
DQLWKLMNSG TAHDWRLRCG AVDLYFTLFG LSRPSCLPLP ELGLVLNLKE
1010 1020 1030 1040 1050
KKAVLNPTII PEAGVGNQES ASNPGCHAQL AGFQNPFSSS QDEEEVDMDT
1060 1070 1080 1090 1100
VHDSQAFISH HLNMLERPST PGLSKYRPSG SRSSLMPQHS LGCDITPPTK
1110 1120 1130 1140 1150
PQWSMELSRK GAGKEQPLEM GVHSMVAAPL SMFAKEALSS RHSEHHHHHH
1160 1170 1180 1190
HEHKKKKKKH KHKHKHKHKH DSKDKDREPF AFSSPASGRS VRSPSLSD
Length:1,198
Mass (Da):136,926
Last modified:March 24, 2009 - v1
Checksum:i9FA604069E20829C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC137950 Genomic DNA. No translation available.
BC147638 mRNA. Translation: AAI47639.1.
BC151079 mRNA. Translation: AAI51080.1.
RefSeqiNP_001074757.1. NM_001081288.1.
UniGeneiMm.380957.

Genome annotation databases

EnsembliENSMUST00000041733; ENSMUSP00000043733; ENSMUSG00000037343.
GeneIDi319944.
KEGGimmu:319944.
UCSCiuc007vrt.1. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC137950 Genomic DNA. No translation available.
BC147638 mRNA. Translation: AAI47639.1 .
BC151079 mRNA. Translation: AAI51080.1 .
RefSeqi NP_001074757.1. NM_001081288.1.
UniGenei Mm.380957.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENSMUST00000041733 ; ENSMUSP00000043733 ; ENSMUSG00000037343 .
GeneIDi 319944.
KEGGi mmu:319944.
UCSCi uc007vrt.1. mouse.

Organism-specific databases

CTDi 6873.
MGIi MGI:2443028. Taf2.

Phylogenomic databases

GeneTreei ENSGT00390000000420.
HOGENOMi HOG000046103.
HOVERGENi HBG094022.
KOi K03128.
OMAi CHSESKQ.
OrthoDBi EOG7R2BHS.
TreeFami TF315208.

Enzyme and pathway databases

Reactomei REACT_230204. RNA Polymerase II Transcription Initiation And Promoter Clearance.
REACT_232708. RNA Polymerase II Transcription Pre-Initiation And Promoter Opening.
REACT_244380. RNA Polymerase II Transcription Initiation.
REACT_255009. RNA Polymerase II Pre-transcription Events.
REACT_255334. RNA Polymerase II Promoter Escape.

Miscellaneous databases

ChiTaRSi Taf2. mouse.
NextBioi 395709.
SOURCEi Search...

Gene expression databases

Genevestigatori B9EJX5.

Family and domain databases

InterProi IPR016024. ARM-type_fold.
IPR014782. Peptidase_M1_N.
[Graphical view ]
Pfami PF01433. Peptidase_M1. 1 hit.
[Graphical view ]
SUPFAMi SSF48371. SSF48371. 1 hit.
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Gerhard D.S., Wagner L., Feingold E.A., Shenmen C.M., Grouse L.H., Schuler G., Klein S.L., Old S., Rasooly R., Good P., Guyer M., Peck A.M., Derge J.G., Lipman D., Collins F.S., Jang W., Sherry S., Feolo M.
    , Misquitta L., Lee E., Rotmistrovsky K., Greenhut S.F., Schaefer C.F., Buetow K., Bonner T.I., Haussler D., Kent J., Kiekhaus M., Furey T., Brent M., Prange C., Schreiber K., Shapiro N., Bhat N.K., Hopkins R.F., Hsie F., Driscoll T., Soares M.B., Casavant T.L., Scheetz T.E., Brown-stein M.J., Usdin T.B., Toshiyuki S., Carninci P., Piao Y., Dudekula D.B., Ko M.S., Kawakami K., Suzuki Y., Sugano S., Gruber C.E., Smith M.R., Simmons B., Moore T., Waterman R., Johnson S.L., Ruan Y., Wei C.L., Mathavan S., Gunaratne P.H., Wu J., Garcia A.M., Hulyk S.W., Fuh E., Yuan Y., Sneed A., Kowis C., Hodgson A., Muzny D.M., McPherson J., Gibbs R.A., Fahey J., Helton E., Ketteman M., Madan A., Rodrigues S., Sanchez A., Whiting M., Madari A., Young A.C., Wetherby K.D., Granite S.J., Kwong P.N., Brinkley C.P., Pearson R.L., Bouffard G.G., Blakesly R.W., Green E.D., Dickson M.C., Rodriguez A.C., Grimwood J., Schmutz J., Myers R.M., Butterfield Y.S., Griffith M., Griffith O.L., Krzywinski M.I., Liao N., Morin R., Morrin R., Palmquist D., Petrescu A.S., Skalska U., Smailus D.E., Stott J.M., Schnerch A., Schein J.E., Jones S.J., Holt R.A., Baross A., Marra M.A., Clifton S., Makowski K.A., Bosak S., Malek J.
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: BrainImported and TesticleImported.
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: C57BL/6JImported.
  3. Ensembl
    Submitted (FEB-2012) to UniProtKB
    Cited for: IDENTIFICATION.
    Strain: C57BL/6JImported.

Entry informationi

Entry nameiB9EJX5_MOUSE
AccessioniPrimary (citable) accession number: B9EJX5
Entry historyi
Integrated into UniProtKB/TrEMBL: March 24, 2009
Last sequence update: March 24, 2009
Last modified: November 26, 2014
This is version 39 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3