Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein
Submitted name:

Cask protein

Gene

Cask

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

Names & Taxonomyi

Protein namesi
Submitted name:
Cask proteinImported
Gene namesi
Name:CaskImported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus

Organism-specific databases

MGIiMGI:1309489 Cask

PTM / Processingi

Proteomic databases

MaxQBiB9EJ23
PeptideAtlasiB9EJ23
PRIDEiB9EJ23

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini12 – 276Protein kinaseInterPro annotationAdd BLAST265
Domaini337 – 392L27InterPro annotationAdd BLAST56
Domaini396 – 449L27InterPro annotationAdd BLAST54
Domaini484 – 565PDZInterPro annotationAdd BLAST82
Domaini571 – 641SH3InterPro annotationAdd BLAST71
Domaini693 – 865Guanylate kinase-likeInterPro annotationAdd BLAST173

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili536 – 556Sequence analysisAdd BLAST21

Sequence similaritiesi

Belongs to the MAGUK family.SAAS annotation

Keywords - Domaini

Coiled coilSequence analysis, SH3 domainPROSITE-ProRule annotationSAAS annotation

Phylogenomic databases

eggNOGiKOG0033 Eukaryota
KOG0609 Eukaryota
COG0194 LUCA
HOVERGENiHBG001858

Family and domain databases

CDDicd12081 SH3_CASK, 1 hit
InterProiView protein in InterPro
IPR035473 CASK_SH3
IPR008145 GK/Ca_channel_bsu
IPR008144 Guanylate_kin-like_dom
IPR020590 Guanylate_kinase_CS
IPR011009 Kinase-like_dom_sf
IPR014775 L27_C
IPR004172 L27_dom
IPR036892 L27_dom_sf
IPR027417 P-loop_NTPase
IPR001478 PDZ
IPR036034 PDZ_sf
IPR000719 Prot_kinase_dom
IPR036028 SH3-like_dom_sf
IPR001452 SH3_domain
PfamiView protein in Pfam
PF00625 Guanylate_kin, 1 hit
PF02828 L27, 2 hits
PF00595 PDZ, 1 hit
PF00069 Pkinase, 1 hit
PF07653 SH3_2, 1 hit
SMARTiView protein in SMART
SM00072 GuKc, 1 hit
SM00569 L27, 2 hits
SM00228 PDZ, 1 hit
SM00326 SH3, 1 hit
SUPFAMiSSF101288 SSF101288, 2 hits
SSF50044 SSF50044, 1 hit
SSF50156 SSF50156, 1 hit
SSF52540 SSF52540, 1 hit
SSF56112 SSF56112, 1 hit
PROSITEiView protein in PROSITE
PS00856 GUANYLATE_KINASE_1, 1 hit
PS50052 GUANYLATE_KINASE_2, 1 hit
PS51022 L27, 2 hits
PS50106 PDZ, 1 hit
PS50011 PROTEIN_KINASE_DOM, 1 hit
PS50002 SH3, 1 hit

Sequencei

Sequence statusi: Complete.

B9EJ23-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MADDDVLFED VYELCEVIGK GPFSVVRRCI NRETGQQFAV KIVDVAKFTS
60 70 80 90 100
SPGLSTEDLK REASICHMLK HPHIVELLET YSSDGMLYMV FEFMDGADLC
110 120 130 140 150
FEIVKRADAG FVYSEAVASH YMRQILEALR YCHDNNIIHR DVKPHCVLLA
160 170 180 190 200
SKENSAPVKL GGFGVAIQLG ESGLVAGGRV GTPHFMAPEV VKREPYGKPV
210 220 230 240 250
DVWGCGVILF ILLSGCLPFY GTKERLFEGI IKGKYKMNPR QWSHISESAK
260 270 280 290 300
DLVRRMLMLD PAERITVYEA LNHPWLKERD RYAYKIHLPE TVEQLRKFNA
310 320 330 340 350
RRKLKGAVLA AVSSHKFNSF YGDPPEELPD FSEDPTSSGA VSQVLDSLEE
360 370 380 390 400
IHALTDCSEK DLDFLHSVFQ DQHLHTLLDL YDKINTKSSP QIRNPPSDAV
410 420 430 440 450
QRAKEVLEEI SCYPENNDAK ELKRILTQPH FMALLQTHDV VAHEVYSDEA
460 470 480 490 500
LRVTPPPTSP YLNGDSPESA NGDMDMENVT RVRLVQFQKN TDEPMGITLK
510 520 530 540 550
MNELNHCIVA RIMHGGMIHR QGTLHVGDEI REINGISVAN QTVEQLQKML
560 570 580 590 600
REMRGSITFK IVPSYRTQSS SCEIYVRAQF EYDPAKDDLI PCKEAGIRFR
610 620 630 640 650
VGDIIQIISK DDHNWWQGKL ENSKNGTAGL IPSPELQEWR VACIAMEKTK
660 670 680 690 700
QEQQASCTWF GKKKKQYKDK YLAKHNADLV TYEEVVKLPA FKRKTLVLLG
710 720 730 740 750
AHGVGRRHIK NTLITKHPDR FAYPIPHTTR PPKKDEENGK NYYFVSHDQM
760 770 780 790 800
MQDISNNEYL EYGSHEDAMY GTKLETIRKI HEQGLIAILD VEPQALKVLR
810 820 830 840 850
TAEFAPFVVF IAAPTITPGL NEDESLQRLQ KESDVLQRTY AHYFDLTIIN
860 870 880
NEIDETIRHL EEAVELVCTA PQWVPVSWVY
Length:880
Mass (Da):100,187
Last modified:March 24, 2009 - v1
Checksum:i3F51FB48B8E5A390
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC141292 mRNA Translation: AAI41293.1
RefSeqiNP_001271433.1, NM_001284504.1
UniGeneiMm.327591
Mm.474948

Genome annotation databases

GeneIDi12361
UCSCiuc012hfa.2 mouse

Similar proteinsi

Entry informationi

Entry nameiB9EJ23_MOUSE
AccessioniPrimary (citable) accession number: B9EJ23
Entry historyiIntegrated into UniProtKB/TrEMBL: March 24, 2009
Last sequence update: March 24, 2009
Last modified: May 23, 2018
This is version 83 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health