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B9EHK8

- B9EHK8_MOUSE

UniProt

B9EHK8 - B9EHK8_MOUSE

Protein
Submitted name:

Homeo box A1

Gene

Hoxa1

Organism
Mus musculus (Mouse)
Status
Unreviewed - Annotation score: 5 out of 5- Experimental evidence at transcript leveli
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    • History
      Entry version 41 (01 Oct 2014)
      Sequence version 1 (24 Mar 2009)
      Previous versions | rss
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    Functioni

    GO - Molecular functioni

    1. sequence-specific DNA binding Source: InterPro
    2. sequence-specific DNA binding transcription factor activity Source: InterPro

    GO - Biological processi

    1. abducens nerve formation Source: Ensembl
    2. anatomical structure formation involved in morphogenesis Source: MGI
    3. anatomical structure morphogenesis Source: MGI
    4. anterior/posterior pattern specification Source: MGI
    5. artery morphogenesis Source: Ensembl
    6. central nervous system neuron differentiation Source: MGI
    7. cochlea morphogenesis Source: Ensembl
    8. cognition Source: Ensembl
    9. embryonic neurocranium morphogenesis Source: Ensembl
    10. facial nerve structural organization Source: MGI
    11. facial nucleus development Source: MGI
    12. hindbrain development Source: MGI
    13. inner ear morphogenesis Source: MGI
    14. motor neuron axon guidance Source: MGI
    15. nervous system development Source: MGI
    16. neuromuscular process Source: Ensembl
    17. optokinetic behavior Source: Ensembl
    18. outer ear morphogenesis Source: Ensembl
    19. positive regulation of transcription from RNA polymerase II promoter Source: MGI
    20. regulation of behavior Source: Ensembl
    21. regulation of transcription from RNA polymerase II promoter Source: MGI
    22. rhombomere 3 development Source: MGI
    23. rhombomere 4 development Source: MGI
    24. rhombomere 5 development Source: MGI
    25. semicircular canal formation Source: Ensembl
    26. sensory perception of sound Source: Ensembl

    Keywords - Ligandi

    DNA-bindingUniRule annotationSAAS annotation

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Homeo box A1Imported
    Gene namesi
    Name:Hoxa1Imported
    OrganismiMus musculus (Mouse)Imported
    Taxonomic identifieri10090 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

    Organism-specific databases

    MGIiMGI:96170. Hoxa1.

    Subcellular locationi

    Nucleus UniRule annotation

    GO - Cellular componenti

    1. nucleus Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    NucleusUniRule annotationSAAS annotation

    Expressioni

    Gene expression databases

    ArrayExpressiB9EHK8.
    BgeeiB9EHK8.
    GenevestigatoriB9EHK8.

    Interactioni

    Protein-protein interaction databases

    STRINGi10090.ENSMUSP00000000964.

    Family & Domainsi

    Sequence similaritiesi

    Contains homeobox DNA-binding domain.SAAS annotation

    Keywords - Domaini

    HomeoboxUniRule annotationSAAS annotation

    Phylogenomic databases

    HOGENOMiHOG000247020.
    HOVERGENiHBG006089.
    PhylomeDBiB9EHK8.

    Family and domain databases

    Gene3Di1.10.10.60. 1 hit.
    InterProiIPR017970. Homeobox_CS.
    IPR001356. Homeobox_dom.
    IPR020479. Homeobox_metazoa.
    IPR009057. Homeodomain-like.
    [Graphical view]
    PfamiPF00046. Homeobox. 1 hit.
    [Graphical view]
    PRINTSiPR00024. HOMEOBOX.
    SMARTiSM00389. HOX. 1 hit.
    [Graphical view]
    SUPFAMiSSF46689. SSF46689. 1 hit.
    PROSITEiPS00027. HOMEOBOX_1. 1 hit.
    PS50071. HOMEOBOX_2. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    B9EHK8-1 [UniParc]FASTAAdd to Basket

    « Hide

    MDNARMNSFL EYPILGSGDS GTCSARAYPS DHGITTFQSC AVSANSCGGD    50
    DRFLVGRGVQ ISSPHHHHHH HHHHHHPQTA TYQTSGNLGI SYSHSSCGPS 100
    YGAQNFSAPY GPYGLNQEAD VSGGYPPCAP AVYSGNLSTP MVQHHHHHQG 150
    YAGGTVGSPQ YIHHSYGQEQ QTLALATYNN SLSPLHASHQ EACRSPASET 200
    SSPAQTFDWM KVKRNPPKTG KVGEYGYVGQ PNAVRTNFTT KQLTELEKEF 250
    HFNKYLTRAR RVEIAASLQL NETQVKIWFQ NRRMKQKKRE KEGLLPISPA 300
    TPPGSDEKTE ESSEKSSPSP SAPSPASSTS DTLTTSH 337
    Length:337
    Mass (Da):36,761
    Last modified:March 24, 2009 - v1
    Checksum:i5BE0FC3142D28DB2
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    BC138098 mRNA. Translation: AAI38099.1.
    UniGeneiMm.197.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    BC138098 mRNA. Translation: AAI38099.1 .
    UniGenei Mm.197.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 10090.ENSMUSP00000000964.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Organism-specific databases

    MGIi MGI:96170. Hoxa1.

    Phylogenomic databases

    HOGENOMi HOG000247020.
    HOVERGENi HBG006089.
    PhylomeDBi B9EHK8.

    Miscellaneous databases

    NextBioi 35547937.
    SOURCEi Search...

    Gene expression databases

    ArrayExpressi B9EHK8.
    Bgeei B9EHK8.
    Genevestigatori B9EHK8.

    Family and domain databases

    Gene3Di 1.10.10.60. 1 hit.
    InterProi IPR017970. Homeobox_CS.
    IPR001356. Homeobox_dom.
    IPR020479. Homeobox_metazoa.
    IPR009057. Homeodomain-like.
    [Graphical view ]
    Pfami PF00046. Homeobox. 1 hit.
    [Graphical view ]
    PRINTSi PR00024. HOMEOBOX.
    SMARTi SM00389. HOX. 1 hit.
    [Graphical view ]
    SUPFAMi SSF46689. SSF46689. 1 hit.
    PROSITEi PS00027. HOMEOBOX_1. 1 hit.
    PS50071. HOMEOBOX_2. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Gerhard D.S., Wagner L., Feingold E.A., Shenmen C.M., Grouse L.H., Schuler G., Klein S.L., Old S., Rasooly R., Good P., Guyer M., Peck A.M., Derge J.G., Lipman D., Collins F.S., Jang W., Sherry S., Feolo M.
      , Misquitta L., Lee E., Rotmistrovsky K., Greenhut S.F., Schaefer C.F., Buetow K., Bonner T.I., Haussler D., Kent J., Kiekhaus M., Furey T., Brent M., Prange C., Schreiber K., Shapiro N., Bhat N.K., Hopkins R.F., Hsie F., Driscoll T., Soares M.B., Casavant T.L., Scheetz T.E., Brown-stein M.J., Usdin T.B., Toshiyuki S., Carninci P., Piao Y., Dudekula D.B., Ko M.S., Kawakami K., Suzuki Y., Sugano S., Gruber C.E., Smith M.R., Simmons B., Moore T., Waterman R., Johnson S.L., Ruan Y., Wei C.L., Mathavan S., Gunaratne P.H., Wu J., Garcia A.M., Hulyk S.W., Fuh E., Yuan Y., Sneed A., Kowis C., Hodgson A., Muzny D.M., McPherson J., Gibbs R.A., Fahey J., Helton E., Ketteman M., Madan A., Rodrigues S., Sanchez A., Whiting M., Madari A., Young A.C., Wetherby K.D., Granite S.J., Kwong P.N., Brinkley C.P., Pearson R.L., Bouffard G.G., Blakesly R.W., Green E.D., Dickson M.C., Rodriguez A.C., Grimwood J., Schmutz J., Myers R.M., Butterfield Y.S., Griffith M., Griffith O.L., Krzywinski M.I., Liao N., Morin R., Morrin R., Palmquist D., Petrescu A.S., Skalska U., Smailus D.E., Stott J.M., Schnerch A., Schein J.E., Jones S.J., Holt R.A., Baross A., Marra M.A., Clifton S., Makowski K.A., Bosak S., Malek J.
      Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
      Tissue: BrainImported.

    Entry informationi

    Entry nameiB9EHK8_MOUSE
    AccessioniPrimary (citable) accession number: B9EHK8
    Entry historyi
    Integrated into UniProtKB/TrEMBL: March 24, 2009
    Last sequence update: March 24, 2009
    Last modified: October 1, 2014
    This is version 41 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)