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B9EHK8

- B9EHK8_MOUSE

UniProt

B9EHK8 - B9EHK8_MOUSE

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Protein
Submitted name:

Homeo box A1

Gene
Hoxa1
Organism
Mus musculus (Mouse)
Status
Unreviewed - Annotation score: 5 out of 5 - Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  1. sequence-specific DNA binding Source: InterPro
  2. sequence-specific DNA binding transcription factor activity Source: InterPro

GO - Biological processi

  1. abducens nerve formation Source: Ensembl
  2. anatomical structure formation involved in morphogenesis Source: MGI
  3. anatomical structure morphogenesis Source: MGI
  4. anterior/posterior pattern specification Source: MGI
  5. artery morphogenesis Source: Ensembl
  6. central nervous system neuron differentiation Source: MGI
  7. cochlea morphogenesis Source: Ensembl
  8. cognition Source: Ensembl
  9. embryonic neurocranium morphogenesis Source: Ensembl
  10. facial nerve structural organization Source: MGI
  11. facial nucleus development Source: MGI
  12. hindbrain development Source: MGI
  13. inner ear morphogenesis Source: MGI
  14. motor neuron axon guidance Source: MGI
  15. nervous system development Source: MGI
  16. neuromuscular process Source: Ensembl
  17. optokinetic behavior Source: Ensembl
  18. outer ear morphogenesis Source: Ensembl
  19. positive regulation of transcription from RNA polymerase II promoter Source: MGI
  20. regulation of behavior Source: Ensembl
  21. regulation of transcription from RNA polymerase II promoter Source: MGI
  22. rhombomere 3 development Source: MGI
  23. rhombomere 4 development Source: MGI
  24. rhombomere 5 development Source: MGI
  25. semicircular canal formation Source: Ensembl
  26. sensory perception of sound Source: Ensembl
Complete GO annotation...

Keywords - Ligandi

DNA-bindingUniRule annotationSAAS annotations

Names & Taxonomyi

Protein namesi
Submitted name:
Homeo box A1Imported
Gene namesi
Name:Hoxa1Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

Organism-specific databases

MGIiMGI:96170. Hoxa1.

Subcellular locationi

Nucleus By similarity UniRule annotation

GO - Cellular componenti

  1. nucleus Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

NucleusUniRule annotationSAAS annotations

Expressioni

Gene expression databases

ArrayExpressiB9EHK8.
BgeeiB9EHK8.
GenevestigatoriB9EHK8.

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000000964.

Family & Domainsi

Sequence similaritiesi

Contains homeobox DNA-binding domain.SAAS annotations

Keywords - Domaini

HomeoboxUniRule annotationSAAS annotations

Phylogenomic databases

HOGENOMiHOG000247020.
HOVERGENiHBG006089.
PhylomeDBiB9EHK8.

Family and domain databases

Gene3Di1.10.10.60. 1 hit.
InterProiIPR017970. Homeobox_CS.
IPR001356. Homeobox_dom.
IPR020479. Homeobox_metazoa.
IPR009057. Homeodomain-like.
[Graphical view]
PfamiPF00046. Homeobox. 1 hit.
[Graphical view]
PRINTSiPR00024. HOMEOBOX.
SMARTiSM00389. HOX. 1 hit.
[Graphical view]
SUPFAMiSSF46689. SSF46689. 1 hit.
PROSITEiPS00027. HOMEOBOX_1. 1 hit.
PS50071. HOMEOBOX_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

B9EHK8-1 [UniParc]FASTAAdd to Basket

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MDNARMNSFL EYPILGSGDS GTCSARAYPS DHGITTFQSC AVSANSCGGD    50
DRFLVGRGVQ ISSPHHHHHH HHHHHHPQTA TYQTSGNLGI SYSHSSCGPS 100
YGAQNFSAPY GPYGLNQEAD VSGGYPPCAP AVYSGNLSTP MVQHHHHHQG 150
YAGGTVGSPQ YIHHSYGQEQ QTLALATYNN SLSPLHASHQ EACRSPASET 200
SSPAQTFDWM KVKRNPPKTG KVGEYGYVGQ PNAVRTNFTT KQLTELEKEF 250
HFNKYLTRAR RVEIAASLQL NETQVKIWFQ NRRMKQKKRE KEGLLPISPA 300
TPPGSDEKTE ESSEKSSPSP SAPSPASSTS DTLTTSH 337
Length:337
Mass (Da):36,761
Last modified:March 24, 2009 - v1
Checksum:i5BE0FC3142D28DB2
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
BC138098 mRNA. Translation: AAI38099.1.
UniGeneiMm.197.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
BC138098 mRNA. Translation: AAI38099.1 .
UniGenei Mm.197.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 10090.ENSMUSP00000000964.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Organism-specific databases

MGIi MGI:96170. Hoxa1.

Phylogenomic databases

HOGENOMi HOG000247020.
HOVERGENi HBG006089.
PhylomeDBi B9EHK8.

Miscellaneous databases

NextBioi 35547937.
SOURCEi Search...

Gene expression databases

ArrayExpressi B9EHK8.
Bgeei B9EHK8.
Genevestigatori B9EHK8.

Family and domain databases

Gene3Di 1.10.10.60. 1 hit.
InterProi IPR017970. Homeobox_CS.
IPR001356. Homeobox_dom.
IPR020479. Homeobox_metazoa.
IPR009057. Homeodomain-like.
[Graphical view ]
Pfami PF00046. Homeobox. 1 hit.
[Graphical view ]
PRINTSi PR00024. HOMEOBOX.
SMARTi SM00389. HOX. 1 hit.
[Graphical view ]
SUPFAMi SSF46689. SSF46689. 1 hit.
PROSITEi PS00027. HOMEOBOX_1. 1 hit.
PS50071. HOMEOBOX_2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Gerhard D.S., Wagner L., Feingold E.A., Shenmen C.M., Grouse L.H., Schuler G., Klein S.L., Old S., Rasooly R., Good P., Guyer M., Peck A.M., Derge J.G., Lipman D., Collins F.S., Jang W., Sherry S., Feolo M.
    , Misquitta L., Lee E., Rotmistrovsky K., Greenhut S.F., Schaefer C.F., Buetow K., Bonner T.I., Haussler D., Kent J., Kiekhaus M., Furey T., Brent M., Prange C., Schreiber K., Shapiro N., Bhat N.K., Hopkins R.F., Hsie F., Driscoll T., Soares M.B., Casavant T.L., Scheetz T.E., Brown-stein M.J., Usdin T.B., Toshiyuki S., Carninci P., Piao Y., Dudekula D.B., Ko M.S., Kawakami K., Suzuki Y., Sugano S., Gruber C.E., Smith M.R., Simmons B., Moore T., Waterman R., Johnson S.L., Ruan Y., Wei C.L., Mathavan S., Gunaratne P.H., Wu J., Garcia A.M., Hulyk S.W., Fuh E., Yuan Y., Sneed A., Kowis C., Hodgson A., Muzny D.M., McPherson J., Gibbs R.A., Fahey J., Helton E., Ketteman M., Madan A., Rodrigues S., Sanchez A., Whiting M., Madari A., Young A.C., Wetherby K.D., Granite S.J., Kwong P.N., Brinkley C.P., Pearson R.L., Bouffard G.G., Blakesly R.W., Green E.D., Dickson M.C., Rodriguez A.C., Grimwood J., Schmutz J., Myers R.M., Butterfield Y.S., Griffith M., Griffith O.L., Krzywinski M.I., Liao N., Morin R., Morrin R., Palmquist D., Petrescu A.S., Skalska U., Smailus D.E., Stott J.M., Schnerch A., Schein J.E., Jones S.J., Holt R.A., Baross A., Marra M.A., Clifton S., Makowski K.A., Bosak S., Malek J.
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: BrainImported.

Entry informationi

Entry nameiB9EHK8_MOUSE
AccessioniPrimary (citable) accession number: B9EHK8
Entry historyi
Integrated into UniProtKB/TrEMBL: March 24, 2009
Last sequence update: March 24, 2009
Last modified: July 9, 2014
This is version 40 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

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