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Protein
Submitted name:

Homeo box A1

Gene

Hoxa1

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 5 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

  • abducens nerve formation Source: MGI
  • anatomical structure formation involved in morphogenesis Source: MGI
  • anatomical structure morphogenesis Source: MGI
  • anterior/posterior pattern specification Source: MGI
  • artery development Source: MGI
  • artery morphogenesis Source: MGI
  • cellular response to retinoic acid Source: MGI
  • central nervous system neuron differentiation Source: MGI
  • cochlea development Source: MGI
  • cochlea morphogenesis Source: MGI
  • cognition Source: MGI
  • embryonic neurocranium morphogenesis Source: MGI
  • facial nerve structural organization Source: MGI
  • facial nucleus development Source: MGI
  • hindbrain development Source: MGI
  • inner ear development Source: MGI
  • inner ear morphogenesis Source: MGI
  • motor neuron axon guidance Source: MGI
  • nervous system development Source: MGI
  • neuromuscular process Source: MGI
  • optokinetic behavior Source: MGI
  • outer ear morphogenesis Source: MGI
  • positive regulation of transcription from RNA polymerase II promoter Source: MGI
  • regulation of behavior Source: MGI
  • regulation of transcription from RNA polymerase II promoter Source: MGI
  • rhombomere 3 development Source: MGI
  • rhombomere 4 development Source: MGI
  • rhombomere 5 development Source: MGI
  • semicircular canal formation Source: MGI
  • sensory perception of sound Source: MGI
Complete GO annotation...

Keywords - Ligandi

DNA-bindingUniRule annotationSAAS annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Homeo box A1Imported
Gene namesi
Name:Hoxa1Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

Organism-specific databases

MGIiMGI:96170. Hoxa1.

Subcellular locationi

  • Nucleus UniRule annotation

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

NucleusUniRule annotationSAAS annotation

Expressioni

Gene expression databases

BgeeiB9EHK8.
ExpressionAtlasiB9EHK8. baseline and differential.

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000000964.

Family & Domainsi

Sequence similaritiesi

Contains homeobox DNA-binding domain.SAAS annotation

Keywords - Domaini

HomeoboxUniRule annotationSAAS annotation

Phylogenomic databases

HOGENOMiHOG000247020.
HOVERGENiHBG006089.
PhylomeDBiB9EHK8.

Family and domain databases

Gene3Di1.10.10.60. 1 hit.
InterProiIPR017970. Homeobox_CS.
IPR001356. Homeobox_dom.
IPR020479. Homeobox_metazoa.
IPR009057. Homeodomain-like.
[Graphical view]
PfamiPF00046. Homeobox. 1 hit.
[Graphical view]
PRINTSiPR00024. HOMEOBOX.
SMARTiSM00389. HOX. 1 hit.
[Graphical view]
SUPFAMiSSF46689. SSF46689. 1 hit.
PROSITEiPS00027. HOMEOBOX_1. 1 hit.
PS50071. HOMEOBOX_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

B9EHK8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDNARMNSFL EYPILGSGDS GTCSARAYPS DHGITTFQSC AVSANSCGGD
60 70 80 90 100
DRFLVGRGVQ ISSPHHHHHH HHHHHHPQTA TYQTSGNLGI SYSHSSCGPS
110 120 130 140 150
YGAQNFSAPY GPYGLNQEAD VSGGYPPCAP AVYSGNLSTP MVQHHHHHQG
160 170 180 190 200
YAGGTVGSPQ YIHHSYGQEQ QTLALATYNN SLSPLHASHQ EACRSPASET
210 220 230 240 250
SSPAQTFDWM KVKRNPPKTG KVGEYGYVGQ PNAVRTNFTT KQLTELEKEF
260 270 280 290 300
HFNKYLTRAR RVEIAASLQL NETQVKIWFQ NRRMKQKKRE KEGLLPISPA
310 320 330
TPPGSDEKTE ESSEKSSPSP SAPSPASSTS DTLTTSH
Length:337
Mass (Da):36,761
Last modified:March 24, 2009 - v1
Checksum:i5BE0FC3142D28DB2
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC138098 mRNA. Translation: AAI38099.1.
UniGeneiMm.197.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC138098 mRNA. Translation: AAI38099.1.
UniGeneiMm.197.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000000964.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Organism-specific databases

MGIiMGI:96170. Hoxa1.

Phylogenomic databases

HOGENOMiHOG000247020.
HOVERGENiHBG006089.
PhylomeDBiB9EHK8.

Miscellaneous databases

NextBioi35547937.
SOURCEiSearch...

Gene expression databases

BgeeiB9EHK8.
ExpressionAtlasiB9EHK8. baseline and differential.

Family and domain databases

Gene3Di1.10.10.60. 1 hit.
InterProiIPR017970. Homeobox_CS.
IPR001356. Homeobox_dom.
IPR020479. Homeobox_metazoa.
IPR009057. Homeodomain-like.
[Graphical view]
PfamiPF00046. Homeobox. 1 hit.
[Graphical view]
PRINTSiPR00024. HOMEOBOX.
SMARTiSM00389. HOX. 1 hit.
[Graphical view]
SUPFAMiSSF46689. SSF46689. 1 hit.
PROSITEiPS00027. HOMEOBOX_1. 1 hit.
PS50071. HOMEOBOX_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Gerhard D.S., Wagner L., Feingold E.A., Shenmen C.M., Grouse L.H., Schuler G., Klein S.L., Old S., Rasooly R., Good P., Guyer M., Peck A.M., Derge J.G., Lipman D., Collins F.S., Jang W., Sherry S., Feolo M.
    , Misquitta L., Lee E., Rotmistrovsky K., Greenhut S.F., Schaefer C.F., Buetow K., Bonner T.I., Haussler D., Kent J., Kiekhaus M., Furey T., Brent M., Prange C., Schreiber K., Shapiro N., Bhat N.K., Hopkins R.F., Hsie F., Driscoll T., Soares M.B., Casavant T.L., Scheetz T.E., Brown-stein M.J., Usdin T.B., Toshiyuki S., Carninci P., Piao Y., Dudekula D.B., Ko M.S., Kawakami K., Suzuki Y., Sugano S., Gruber C.E., Smith M.R., Simmons B., Moore T., Waterman R., Johnson S.L., Ruan Y., Wei C.L., Mathavan S., Gunaratne P.H., Wu J., Garcia A.M., Hulyk S.W., Fuh E., Yuan Y., Sneed A., Kowis C., Hodgson A., Muzny D.M., McPherson J., Gibbs R.A., Fahey J., Helton E., Ketteman M., Madan A., Rodrigues S., Sanchez A., Whiting M., Madari A., Young A.C., Wetherby K.D., Granite S.J., Kwong P.N., Brinkley C.P., Pearson R.L., Bouffard G.G., Blakesly R.W., Green E.D., Dickson M.C., Rodriguez A.C., Grimwood J., Schmutz J., Myers R.M., Butterfield Y.S., Griffith M., Griffith O.L., Krzywinski M.I., Liao N., Morin R., Morrin R., Palmquist D., Petrescu A.S., Skalska U., Smailus D.E., Stott J.M., Schnerch A., Schein J.E., Jones S.J., Holt R.A., Baross A., Marra M.A., Clifton S., Makowski K.A., Bosak S., Malek J.
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: BrainImported.

Entry informationi

Entry nameiB9EHK8_MOUSE
AccessioniPrimary (citable) accession number: B9EHK8
Entry historyi
Integrated into UniProtKB/TrEMBL: March 24, 2009
Last sequence update: March 24, 2009
Last modified: June 24, 2015
This is version 45 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.