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B9EHK7

- B9EHK7_MOUSE

UniProt

B9EHK7 - B9EHK7_MOUSE

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Protein
Submitted name:

Homeo box A1

Gene

Hoxa1

Organism
Mus musculus (Mouse)
Status
Unreviewed - Annotation score: 5 out of 5- Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  1. sequence-specific DNA binding Source: InterPro

GO - Biological processi

  1. abducens nerve formation Source: Ensembl
  2. anatomical structure formation involved in morphogenesis Source: MGI
  3. anatomical structure morphogenesis Source: MGI
  4. anterior/posterior pattern specification Source: MGI
  5. artery morphogenesis Source: Ensembl
  6. cellular response to retinoic acid Source: MGI
  7. central nervous system neuron differentiation Source: MGI
  8. cochlea morphogenesis Source: Ensembl
  9. cognition Source: Ensembl
  10. embryonic neurocranium morphogenesis Source: Ensembl
  11. facial nerve structural organization Source: MGI
  12. facial nucleus development Source: MGI
  13. hindbrain development Source: MGI
  14. inner ear morphogenesis Source: MGI
  15. motor neuron axon guidance Source: MGI
  16. nervous system development Source: MGI
  17. neuromuscular process Source: Ensembl
  18. optokinetic behavior Source: Ensembl
  19. outer ear morphogenesis Source: Ensembl
  20. positive regulation of transcription from RNA polymerase II promoter Source: MGI
  21. regulation of behavior Source: Ensembl
  22. regulation of transcription from RNA polymerase II promoter Source: MGI
  23. rhombomere 3 development Source: MGI
  24. rhombomere 4 development Source: MGI
  25. rhombomere 5 development Source: MGI
  26. semicircular canal formation Source: Ensembl
  27. sensory perception of sound Source: Ensembl
Complete GO annotation...

Keywords - Ligandi

DNA-bindingUniRule annotationSAAS annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Homeo box A1Imported
Submitted name:
Homeobox A1Imported
Submitted name:
Homeobox protein Hox-A1Imported
Gene namesi
Name:Hoxa1Imported
ORF Names:mCG_121168Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
ProteomesiUP000000589: Chromosome 6

Organism-specific databases

MGIiMGI:96170. Hoxa1.

Subcellular locationi

Nucleus UniRule annotation

GO - Cellular componenti

  1. nucleus Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

NucleusUniRule annotationSAAS annotation

Expressioni

Gene expression databases

GenevestigatoriB9EHK7.

Family & Domainsi

Sequence similaritiesi

Contains homeobox DNA-binding domain.SAAS annotation

Keywords - Domaini

HomeoboxUniRule annotationSAAS annotation

Phylogenomic databases

GeneTreeiENSGT00760000118940.
HOVERGENiHBG006089.
KOiK09301.
OMAiCAVSANS.
OrthoDBiEOG7PK91P.
TreeFamiTF317730.

Family and domain databases

Gene3Di1.10.10.60. 1 hit.
InterProiIPR017970. Homeobox_CS.
IPR001356. Homeobox_dom.
IPR020479. Homeobox_metazoa.
IPR009057. Homeodomain-like.
[Graphical view]
PfamiPF00046. Homeobox. 1 hit.
[Graphical view]
PRINTSiPR00024. HOMEOBOX.
SMARTiSM00389. HOX. 1 hit.
[Graphical view]
SUPFAMiSSF46689. SSF46689. 1 hit.
PROSITEiPS00027. HOMEOBOX_1. 1 hit.
PS50071. HOMEOBOX_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

B9EHK7-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MDNARMNSFL EYPILGSGDS GTCSARAYPS DHGITTFQSC AVSANSCGGD
60 70 80 90 100
DRFLVGRGVQ ISSPHHHHHH HHHHHPQTAT YQTSGNLGIS YSHSSCGPSY
110 120 130 140 150
GAQNFSAPYG PYGLNQEADV SGGYPPCAPA VYSGNLSTPM VQHHHHHQGY
160 170 180 190 200
AGGTVGSPQY IHHSYGQEQQ TLALATYNNS LSPLHASHQE ACRSPASETS
210 220 230 240 250
SPAQTFDWMK VKRNPPKTGK VGEYGYVGQP NAVRTNFTTK QLTELEKEFH
260 270 280 290 300
FNKYLTRARR VEIAASLQLN ETQVKIWFQN RRMKQKKREK EGLLPISPAT
310 320 330
PPGSDEKTEE SSEKSSPSPS APSPASSTSD TLTTSH
Length:336
Mass (Da):36,624
Last modified:March 24, 2009 - v1
Checksum:i52B5E6F7412A9EB5
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC091106 Genomic DNA. No translation available.
BC138097 mRNA. Translation: AAI38098.1.
CH466597 Genomic DNA. Translation: EDK98647.1.
RefSeqiNP_034579.3. NM_010449.4.
XP_006505670.1. XM_006505607.1.
UniGeneiMm.197.

Genome annotation databases

EnsembliENSMUST00000000964; ENSMUSP00000000964; ENSMUSG00000029844.
GeneIDi15394.
KEGGimmu:15394.
UCSCiuc009bxy.1. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC091106 Genomic DNA. No translation available.
BC138097 mRNA. Translation: AAI38098.1 .
CH466597 Genomic DNA. Translation: EDK98647.1 .
RefSeqi NP_034579.3. NM_010449.4.
XP_006505670.1. XM_006505607.1.
UniGenei Mm.197.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENSMUST00000000964 ; ENSMUSP00000000964 ; ENSMUSG00000029844 .
GeneIDi 15394.
KEGGi mmu:15394.
UCSCi uc009bxy.1. mouse.

Organism-specific databases

CTDi 3198.
MGIi MGI:96170. Hoxa1.

Phylogenomic databases

GeneTreei ENSGT00760000118940.
HOVERGENi HBG006089.
KOi K09301.
OMAi CAVSANS.
OrthoDBi EOG7PK91P.
TreeFami TF317730.

Miscellaneous databases

NextBioi 288072.
SOURCEi Search...

Gene expression databases

Genevestigatori B9EHK7.

Family and domain databases

Gene3Di 1.10.10.60. 1 hit.
InterProi IPR017970. Homeobox_CS.
IPR001356. Homeobox_dom.
IPR020479. Homeobox_metazoa.
IPR009057. Homeodomain-like.
[Graphical view ]
Pfami PF00046. Homeobox. 1 hit.
[Graphical view ]
PRINTSi PR00024. HOMEOBOX.
SMARTi SM00389. HOX. 1 hit.
[Graphical view ]
SUPFAMi SSF46689. SSF46689. 1 hit.
PROSITEi PS00027. HOMEOBOX_1. 1 hit.
PS50071. HOMEOBOX_2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "A comparison of whole-genome shotgun-derived mouse chromosome 16 and the human genome."
    Mural R.J., Adams M.D., Myers E.W., Smith H.O., Miklos G.L., Wides R., Halpern A., Li P.W., Sutton G.G., Nadeau J., Salzberg S.L., Holt R.A., Kodira C.D., Lu F., Chen L., Deng Z., Evangelista C.C., Gan W.
    , Heiman T.J., Li J., Li Z., Merkulov G.V., Milshina N.V., Naik A.K., Qi R., Shue B.C., Wang A., Wang J., Wang X., Yan X., Ye J., Yooseph S., Zhao Q., Zheng L., Zhu S.C., Biddick K., Bolanos R., Delcher A.L., Dew I.M., Fasulo D., Flanigan M.J., Huson D.H., Kravitz S.A., Miller J.R., Mobarry C.M., Reinert K., Remington K.A., Zhang Q., Zheng X.H., Nusskern D.R., Lai Z., Lei Y., Zhong W., Yao A., Guan P., Ji R.R., Gu Z., Wang Z.Y., Zhong F., Xiao C., Chiang C.C., Yandell M., Wortman J.R., Amanatides P.G., Hladun S.L., Pratts E.C., Johnson J.E., Dodson K.L., Woodford K.J., Evans C.A., Gropman B., Rusch D.B., Venter E., Wang M., Smith T.J., Houck J.T., Tompkins D.E., Haynes C., Jacob D., Chin S.H., Allen D.R., Dahlke C.E., Sanders R., Li K., Liu X., Levitsky A.A., Majoros W.H., Chen Q., Xia A.C., Lopez J.R., Donnelly M.T., Newman M.H., Glodek A., Kraft C.L., Nodell M., Ali F., An H.J., Baldwin-Pitts D., Beeson K.Y., Cai S., Carnes M., Carver A., Caulk P.M., Center A., Chen Y.H., Cheng M.L., Coyne M.D., Crowder M., Danaher S., Davenport L.B., Desilets R., Dietz S.M., Doup L., Dullaghan P., Ferriera S., Fosler C.R., Gire H.C., Gluecksmann A., Gocayne J.D., Gray J., Hart B., Haynes J., Hoover J., Howland T., Ibegwam C., Jalali M., Johns D., Kline L., Ma D.S., MacCawley S., Magoon A., Mann F., May D., McIntosh T.C., Mehta S., Moy L., Moy M.C., Murphy B.J., Murphy S.D., Nelson K.A., Nuri Z., Parker K.A., Prudhomme A.C., Puri V.N., Qureshi H., Raley J.C., Reardon M.S., Regier M.A., Rogers Y.H., Romblad D.L., Schutz J., Scott J.L., Scott R., Sitter C.D., Smallwood M., Sprague A.C., Stewart E., Strong R.V., Suh E., Sylvester K., Thomas R., Tint N.N., Tsonis C., Wang G., Wang G., Williams M.S., Williams S.M., Windsor S.M., Wolfe K., Wu M.M., Zaveri J., Chaturvedi K., Gabrielian A.E., Ke Z., Sun J., Subramanian G., Venter J.C., Pfannkoch C.M., Barnstead M., Stephenson L.D.
    Science 296:1661-1671(2002) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: MixedImported.
  2. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Gerhard D.S., Wagner L., Feingold E.A., Shenmen C.M., Grouse L.H., Schuler G., Klein S.L., Old S., Rasooly R., Good P., Guyer M., Peck A.M., Derge J.G., Lipman D., Collins F.S., Jang W., Sherry S., Feolo M.
    , Misquitta L., Lee E., Rotmistrovsky K., Greenhut S.F., Schaefer C.F., Buetow K., Bonner T.I., Haussler D., Kent J., Kiekhaus M., Furey T., Brent M., Prange C., Schreiber K., Shapiro N., Bhat N.K., Hopkins R.F., Hsie F., Driscoll T., Soares M.B., Casavant T.L., Scheetz T.E., Brown-stein M.J., Usdin T.B., Toshiyuki S., Carninci P., Piao Y., Dudekula D.B., Ko M.S., Kawakami K., Suzuki Y., Sugano S., Gruber C.E., Smith M.R., Simmons B., Moore T., Waterman R., Johnson S.L., Ruan Y., Wei C.L., Mathavan S., Gunaratne P.H., Wu J., Garcia A.M., Hulyk S.W., Fuh E., Yuan Y., Sneed A., Kowis C., Hodgson A., Muzny D.M., McPherson J., Gibbs R.A., Fahey J., Helton E., Ketteman M., Madan A., Rodrigues S., Sanchez A., Whiting M., Madari A., Young A.C., Wetherby K.D., Granite S.J., Kwong P.N., Brinkley C.P., Pearson R.L., Bouffard G.G., Blakesly R.W., Green E.D., Dickson M.C., Rodriguez A.C., Grimwood J., Schmutz J., Myers R.M., Butterfield Y.S., Griffith M., Griffith O.L., Krzywinski M.I., Liao N., Morin R., Morrin R., Palmquist D., Petrescu A.S., Skalska U., Smailus D.E., Stott J.M., Schnerch A., Schein J.E., Jones S.J., Holt R.A., Baross A., Marra M.A., Clifton S., Makowski K.A., Bosak S., Malek J.
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: TesticleImported.
  3. Mural R.J., Adams M.D., Myers E.W., Smith H.O., Venter J.C.
    Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: MixedImported.
  4. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: C57BL/6JImported.
  5. Ensembl
    Submitted (FEB-2012) to UniProtKB
    Cited for: IDENTIFICATION.
    Strain: C57BL/6JImported.

Entry informationi

Entry nameiB9EHK7_MOUSE
AccessioniPrimary (citable) accession number: B9EHK7
Entry historyi
Integrated into UniProtKB/TrEMBL: March 24, 2009
Last sequence update: March 24, 2009
Last modified: November 26, 2014
This is version 53 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3