B9E150 (TRPF_CLOK1) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
N-(5'-phosphoribosyl)anthranilate isomerase
Short name=PRAI
EC=5.3.1.24

Gene names

Name:	trpF
Ordered Locus Names:	CKR_1174

Organism

Clostridium kluyveri (strain NBRC 12016) [Complete proteome] [HAMAP]

Taxonomic identifier

583346 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Firmicutes › Clostridia › Clostridiales › Clostridiaceae › Clostridium › Clostridium kluyveri

Protein attributes

Sequence length	199 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	N-(5-phospho-beta-D-ribosyl)anthranilate = 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate. HAMAP-Rule MF_00135
Pathway	Amino-acid biosynthesis; L-tryptophan biosynthesis; L-tryptophan from chorismate: step 3/5. HAMAP-Rule MF_00135
Sequence similarities	Belongs to the TrpF family.

Ontologies

Keywords
Biological process	Amino-acid biosynthesis Aromatic amino acid biosynthesis Tryptophan biosynthesis
Molecular function	Isomerase
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	tryptophan biosynthetic process Inferred from electronic annotation. Source: HAMAP
Molecular_function	phosphoribosylanthranilate isomerase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 199	199	N-(5'-phosphoribosyl)anthranilate isomerase HAMAP-Rule MF_00135		PRO_1000197094

Sequences

	Sequence		Length	Mass (Da)
	B9E150 [UniParc]. Last modified March 24, 2009. Version 1. Checksum: E1135957C37E9645	FASTA	199	22,798
	10 20 30 40 50 60 MIKVKICGLK RDEDIKCVNR YKPDYVGFVF SKSKRQVNLE QAKMLIANLD SSIKSVGVFV 70 80 90 100 110 120 DEALEYVYNT SKILALDVIQ FHGLEDEEYM RHFNEFTIWK ALKVRCREDI LNLNYKYADG 130 140 150 160 170 180 IVLDNKTAGS GKCFDWDIAR HIKIKKDLIL AGGINEENVE TAAYIVNPDI VDVSSGVESQ 190 GYKDSSKIKM FIEKVRNIK

References

[1]

"Complete genome sequence of Clostridium kluyveri and comparative genomics of Clostridia species." Inui M., Nonaka H., Shinoda Y., Ikenaga Y., Abe M., Naito K., Vertes A.A., Yukawa H. Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: NBRC 12016.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AP009049 Genomic DNA. Translation: BAH06225.1.
RefSeq	YP_002471639.1. NC_011837.1.
3D structure databases
ProteinModelPortal	B9E150.
ModBase	Search...
Protein-protein interaction databases
STRING	583346.CKR_1174.
Proteomic databases
PRIDE	B9E150.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	BAH06225; BAH06225; CKR_1174.
GeneID	7274754.
KEGG	ckr:CKR_1174.
PATRIC	19472178. VBICloKlu118830_1336.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0135.
HOGENOM	HOG000161598.
KO	K01817.
ProtClustDB	CLSK2474828.
Enzyme and pathway databases
BioCyc	CKLU583346:GJNQ-1219-MONOMER.
UniPathway	UPA00035; UER00042.
Family and domain databases
Gene3D	3.20.20.70. 1 hit.
HAMAP	MF_00135. PRAI.
InterPro	IPR013785. Aldolase_TIM. IPR001240. PRAI. IPR011060. RibuloseP-bd_barrel. [Graphical view]
Pfam	PF00697. PRAI. 1 hit. [Graphical view]
SUPFAM	SSF51366. RibP_bind_barrel. 1 hit.
ProtoNet	Search...

Entry information

Entry name

TRPF_CLOK1

Accession

Primary (citable) accession number: B9E150

Entry history

Integrated into UniProtKB/Swiss-Prot:	July 28, 2009
Last sequence update:	March 24, 2009
Last modified:	May 1, 2013
This is version 27 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program