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Protein
Submitted name:

Putative ribosomal RNA small subunit methyltransferase

Gene

SUB1387

Organism
Streptococcus uberis (strain ATCC BAA-854 / 0140J)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.SAAS annotation

Catalytic activityi

S-adenosyl-L-methionine + cytosine(967) in 16S rRNA = S-adenosyl-L-homocysteine + 5-methylcytosine(967) in 16S rRNA.SAAS annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei280S-adenosyl-L-methioninePROSITE-ProRule annotation1
Binding sitei308S-adenosyl-L-methioninePROSITE-ProRule annotation1
Binding sitei327S-adenosyl-L-methioninePROSITE-ProRule annotation1
Active sitei380NucleophilePROSITE-ProRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionMethyltransferasePROSITE-ProRule annotationSAAS annotationImported, RNA-bindingPROSITE-ProRule annotationSAAS annotation, Transferase
Biological processrRNA processingSAAS annotation
LigandS-adenosyl-L-methioninePROSITE-ProRule annotationSAAS annotation

Enzyme and pathway databases

BioCyciSUBE218495:GJ7D-1387-MONOMER.

Names & Taxonomyi

Protein namesi
Submitted name:
Putative ribosomal RNA small subunit methyltransferaseImported
Gene namesi
Ordered Locus Names:SUB1387Imported
OrganismiStreptococcus uberis (strain ATCC BAA-854 / 0140J)Imported
Taxonomic identifieri218495 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliLactobacillalesStreptococcaceaeStreptococcus
Proteomesi
  • UP000000449 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm SAAS annotation

GO - Cellular componenti

Keywords - Cellular componenti

CytoplasmSAAS annotation

Interactioni

Protein-protein interaction databases

STRINGi218495.SUB1387.

Structurei

3D structure databases

ProteinModelPortaliB9DV44.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini160 – 439SAM_MT_RSMB_NOPInterPro annotationAdd BLAST280

Sequence similaritiesi

Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.PROSITE-ProRule annotationSAAS annotation

Phylogenomic databases

eggNOGiENOG4105CYJ. Bacteria.
COG0144. LUCA.
HOGENOMiHOG000037300.
KOiK03500.
OMAiLRVNRQH.
OrthoDBiPOG091H02E2.

Family and domain databases

Gene3Di1.10.940.10. 1 hit.
InterProiView protein in InterPro
IPR018314. Fmu/NOL1/Nop2p_CS.
IPR001678. MeTrfase_RsmB/NOP2.
IPR006027. NusB_RsmB_TIM44.
IPR023267. RCMT.
IPR004573. rRNA_ssu_MeTfrase_B.
IPR029063. SAM-dependent_MTases.
PfamiView protein in Pfam
PF01189. Methyltr_RsmB-F. 1 hit.
PF01029. NusB. 1 hit.
PRINTSiPR02008. RCMTFAMILY.
SUPFAMiSSF48013. SSF48013. 1 hit.
SSF53335. SSF53335. 1 hit.
TIGRFAMsiTIGR00563. rsmB. 1 hit.
PROSITEiView protein in PROSITE
PS01153. NOL1_NOP2_SUN. 1 hit.
PS51686. SAM_MT_RSMB_NOP. 1 hit.

Sequencei

Sequence statusi: Complete.

B9DV44-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MANNWKREAR GKALMAIEDI FDNGAYSNLA LNQHLNHQAL NAKDKALITE
60 70 80 90 100
IVYGTVSRKL TLEWHLSHVI EDRNRLDKWV YYLLMISLYQ LLYLDKVPQH
110 120 130 140 150
AIVNDAVNIA KNRGNNRGAE KFVNAVLRQL TNHPLPDPSL IKRKNKRYSI
160 170 180 190 200
LYSIPTWLVI KLIDQFGEER ALKIMESLSL NSKISLRVIN LDKMEIIKEA
210 220 230 240 250
LDAEMSLLSP CGLTKENGYM ALHDFFQRGD ITIQDESSQL VAPTLAIQEN
260 270 280 290 300
DIVLDACSAP GGKTSHMASY LKTGKVVALD IHEHKLDLVR ENAERLGLSE
310 320 330 340 350
KIETRLLDAR QVHEVFGPDS FDKILVDAPC SGIGLIRRKP DIKYNKDLQD
360 370 380 390 400
LKQLQAVQLE ILSSVCQTIR KGGIITYSTC TIFDEENVQV IKRFLKEHPN
410 420 430 440
FEQIKLKHTQ AEIVKDGCLV ITPEQFQTDG FFIAQIRRVL
Length:440
Mass (Da):50,091
Last modified:March 24, 2009 - v1
Checksum:iDB1BD175E44F1120
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AM946015 Genomic DNA. Translation: CAR43000.1.
RefSeqiWP_015911707.1. NC_012004.1.

Genome annotation databases

EnsemblBacteriaiCAR43000; CAR43000; SUB1387.
GeneIDi24161365.
KEGGisub:SUB1387.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.

Entry informationi

Entry nameiB9DV44_STRU0
AccessioniPrimary (citable) accession number: B9DV44
Entry historyiIntegrated into UniProtKB/TrEMBL: March 24, 2009
Last sequence update: March 24, 2009
Last modified: June 7, 2017
This is version 63 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported