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Protein

Uronate isomerase

Gene

uxaC

Organism
Streptococcus uberis (strain ATCC BAA-854 / 0140J)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

D-glucuronate = D-fructuronate.UniRule annotation
D-galacturonate = D-tagaturonate.UniRule annotation

Pathwayi: pentose and glucuronate interconversion

This protein is involved in the pathway pentose and glucuronate interconversion, which is part of Carbohydrate metabolism.UniRule annotation
View all proteins of this organism that are known to be involved in the pathway pentose and glucuronate interconversion and in Carbohydrate metabolism.

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Isomerase

Enzyme and pathway databases

BioCyciSUBE218495:GJ7D-1240-MONOMER.
UniPathwayiUPA00246.

Names & Taxonomyi

Protein namesi
Recommended name:
Uronate isomeraseUniRule annotation (EC:5.3.1.12UniRule annotation)
Alternative name(s):
Glucuronate isomeraseUniRule annotation
Uronic isomeraseUniRule annotation
Gene namesi
Name:uxaCUniRule annotation
Ordered Locus Names:SUB1203
OrganismiStreptococcus uberis (strain ATCC BAA-854 / 0140J)
Taxonomic identifieri218495 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliLactobacillalesStreptococcaceaeStreptococcus
Proteomesi
  • UP000000449 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 467467Uronate isomerasePRO_1000147694Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi218495.SUB1203.

Structurei

3D structure databases

ProteinModelPortaliB9DSL9.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the uronate isomerase family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105D2H. Bacteria.
COG1904. LUCA.
HOGENOMiHOG000224075.
KOiK01812.
OMAiGHTDPRW.
OrthoDBiEOG6J1D95.

Family and domain databases

Gene3Di1.10.2020.10. 1 hit.
HAMAPiMF_00675. UxaC.
InterProiIPR032466. Metal_Hydrolase.
IPR003766. Uronate_isomerase.
IPR023177. Uronate_isomerase_dom2.
[Graphical view]
PfamiPF02614. UxaC. 1 hit.
[Graphical view]
SUPFAMiSSF51556. SSF51556. 1 hit.

Sequencei

Sequence statusi: Complete.

B9DSL9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTFNDKNFML KNQAAKQLYT AVQDQPIFDY HCHLDPKEIF EDKVFENIVD
60 70 80 90 100
LWLGGDHYKW RLMRANGISE EEITGSASQL DKFKAFARTL QRSYGNPVYH
110 120 130 140 150
WSAMELKNVF GIEEVLTEEN AEEIYNRLNT YLLENKVSPR KLIADSKVTF
160 170 180 190 200
IGTTDHPLDT LEWHQKLAED KSFETIVAPT FRPDEAFIEH HNFKGFLDKL
210 220 230 240 250
SQATGKEMTE FKDFISAMED RIAYFAENGC KASDISFTEI VFEAAEESEL
260 270 280 290 300
NELLAKVKDG YKPNALEVKQ WQTAVFAELC QLYKKYGFVT QVHFGALRNN
310 320 330 340 350
HSKLYQKLGA DVGIDSLGDQ TALTSNMNKL LDNLVQKDAL PKMIWYNLNP
360 370 380 390 400
SYNIAVANTL ANFQANEEGV KSYLQFGAGW WFADTKLGMI SQMNALAEQG
410 420 430 440 450
MLANFVGMLT DSRSFLSYQR HDYFRRILCT YLGEWIEEGE VPEDYEALGH
460
MAKDIAYHNA VNYFKHE
Length:467
Mass (Da):53,730
Last modified:March 24, 2009 - v1
Checksum:iEE4EB3DDD4799CF5
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AM946015 Genomic DNA. Translation: CAR42641.1.
RefSeqiWP_012658683.1. NC_012004.1.

Genome annotation databases

EnsemblBacteriaiCAR42641; CAR42641; SUB1203.
GeneIDi24162855.
KEGGisub:SUB1203.
PATRICi19808112. VBIStrUbe20775_1172.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AM946015 Genomic DNA. Translation: CAR42641.1.
RefSeqiWP_012658683.1. NC_012004.1.

3D structure databases

ProteinModelPortaliB9DSL9.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi218495.SUB1203.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiCAR42641; CAR42641; SUB1203.
GeneIDi24162855.
KEGGisub:SUB1203.
PATRICi19808112. VBIStrUbe20775_1172.

Phylogenomic databases

eggNOGiENOG4105D2H. Bacteria.
COG1904. LUCA.
HOGENOMiHOG000224075.
KOiK01812.
OMAiGHTDPRW.
OrthoDBiEOG6J1D95.

Enzyme and pathway databases

UniPathwayiUPA00246.
BioCyciSUBE218495:GJ7D-1240-MONOMER.

Family and domain databases

Gene3Di1.10.2020.10. 1 hit.
HAMAPiMF_00675. UxaC.
InterProiIPR032466. Metal_Hydrolase.
IPR003766. Uronate_isomerase.
IPR023177. Uronate_isomerase_dom2.
[Graphical view]
PfamiPF02614. UxaC. 1 hit.
[Graphical view]
SUPFAMiSSF51556. SSF51556. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC BAA-854 / 0140J.

Entry informationi

Entry nameiUXAC_STRU0
AccessioniPrimary (citable) accession number: B9DSL9
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 28, 2009
Last sequence update: March 24, 2009
Last modified: December 9, 2015
This is version 46 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.