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B9DNP9

- EX7L_STACT

UniProt

B9DNP9 - EX7L_STACT

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Protein

Exodeoxyribonuclease 7 large subunit

Gene
xseA, Sca_1147
Organism
Staphylococcus carnosus (strain TM300)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides By similarity.UniRule annotation

Catalytic activityi

Exonucleolytic cleavage in either 5'- to 3'- or 3'- to 5'-direction to yield nucleoside 5'-phosphates.UniRule annotation

GO - Molecular functioni

  1. exodeoxyribonuclease VII activity Source: UniProtKB-HAMAP
  2. nucleic acid binding Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Exonuclease, Hydrolase, Nuclease

Enzyme and pathway databases

BioCyciSCAR396513:GJ9G-1160-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Exodeoxyribonuclease 7 large subunit (EC:3.1.11.6)
Alternative name(s):
Exodeoxyribonuclease VII large subunit
Short name:
Exonuclease VII large subunit
Gene namesi
Name:xseA
Ordered Locus Names:Sca_1147
OrganismiStaphylococcus carnosus (strain TM300)
Taxonomic identifieri396513 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesStaphylococcus
ProteomesiUP000000444: Chromosome

Subcellular locationi

Cytoplasm By similarity UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
  2. exodeoxyribonuclease VII complex Source: InterPro
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 446446Exodeoxyribonuclease 7 large subunitUniRule annotationPRO_1000200680Add
BLAST

Interactioni

Subunit structurei

Heterooligomer composed of large and small subunits By similarity.

Protein-protein interaction databases

STRINGi396513.Sca_1147.

Family & Domainsi

Sequence similaritiesi

Belongs to the XseA family.

Phylogenomic databases

eggNOGiCOG1570.
HOGENOMiHOG000229265.
KOiK03601.
OMAiDDRHKQA.
OrthoDBiEOG64R65J.

Family and domain databases

HAMAPiMF_00378. Exonuc_7_L.
InterProiIPR003753. Exonuc_VII_L.
IPR020579. Exonuc_VII_lsu_C.
IPR025824. OB-fold_nuc-bd_dom.
[Graphical view]
PfamiPF02601. Exonuc_VII_L. 1 hit.
PF13742. tRNA_anti_2. 1 hit.
[Graphical view]
TIGRFAMsiTIGR00237. xseA. 1 hit.

Sequencei

Sequence statusi: Complete.

B9DNP9-1 [UniParc]FASTAAdd to Basket

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MSDYLSVTAL TKYIKYKFDQ DPHLQSVLLK GELSNFKKHS SGHLYFNLKD    50
NNSVVNAMMF KAQANKLDFN PKEGDEVLIE ARVSVYERQG NYQIYVNKMH 100
LDGIGNLYQK LEALKKELKK QGLFDTKHKK EIPRFPKKIA VLTASTGAAI 150
RDIYSTINSR YPLVEQIQIS TLVQGKQAKD DIVNKIKYAD TLDADVMIVG 200
RGGGSIEDLW NFNEEEVVRA IFEAKTPVIS AVGHETDFTL SDFVADVRAA 250
TPTQAAVIAT PDQVELSQYI KQTELNLSRH IIQIINNKKK HLEHVASYYK 300
FKQPSLLYDQ QIQKKDDFER QLNLSITTKL NNALQKVELL TNRINLKDLK 350
QQTLQGIQSR LQLHDSLNKS IINIIDNSKK RLSQRIENLN SLSPSNTMLR 400
GYTIVNKNEQ VITSTQSLEK NDEINLQMKD GTVDAIVKKV RCNHNE 446
Length:446
Mass (Da):50,866
Last modified:March 24, 2009 - v1
Checksum:i52F2B90424B5AF97
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AM295250 Genomic DNA. Translation: CAL28055.1.
RefSeqiWP_015900396.1. NC_012121.1.
YP_002634240.1. NC_012121.1.

Genome annotation databases

GeneIDi7550459.
KEGGisca:Sca_1147.
PATRICi19603064. VBIStaCar105558_1146.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AM295250 Genomic DNA. Translation: CAL28055.1 .
RefSeqi WP_015900396.1. NC_012121.1.
YP_002634240.1. NC_012121.1.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 396513.Sca_1147.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

GeneIDi 7550459.
KEGGi sca:Sca_1147.
PATRICi 19603064. VBIStaCar105558_1146.

Phylogenomic databases

eggNOGi COG1570.
HOGENOMi HOG000229265.
KOi K03601.
OMAi DDRHKQA.
OrthoDBi EOG64R65J.

Enzyme and pathway databases

BioCyci SCAR396513:GJ9G-1160-MONOMER.

Family and domain databases

HAMAPi MF_00378. Exonuc_7_L.
InterProi IPR003753. Exonuc_VII_L.
IPR020579. Exonuc_VII_lsu_C.
IPR025824. OB-fold_nuc-bd_dom.
[Graphical view ]
Pfami PF02601. Exonuc_VII_L. 1 hit.
PF13742. tRNA_anti_2. 1 hit.
[Graphical view ]
TIGRFAMsi TIGR00237. xseA. 1 hit.
ProtoNeti Search...

Publicationsi

  1. "Genome analysis of the meat starter culture bacterium Staphylococcus carnosus TM300."
    Rosenstein R., Nerz C., Biswas L., Resch A., Raddatz G., Schuster S.C., Goetz F.
    Appl. Environ. Microbiol. 75:811-822(2009) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: TM300.

Entry informationi

Entry nameiEX7L_STACT
AccessioniPrimary (citable) accession number: B9DNP9
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 28, 2009
Last sequence update: March 24, 2009
Last modified: September 3, 2014
This is version 40 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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