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Protein

Elongation factor Tu

Gene

tuf

Organism
Staphylococcus carnosus (strain TM300)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.UniRule annotation

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi19 – 26GTPUniRule annotation8
Nucleotide bindingi81 – 85GTPUniRule annotation5
Nucleotide bindingi136 – 139GTPUniRule annotation4

GO - Molecular functioni

Keywordsi

Molecular functionElongation factor
Biological processProtein biosynthesis
LigandGTP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciSCAR396513:SCA_RS01060-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Elongation factor TuUniRule annotation
Short name:
EF-TuUniRule annotation
Gene namesi
Name:tufUniRule annotation
Ordered Locus Names:Sca_0207
OrganismiStaphylococcus carnosus (strain TM300)
Taxonomic identifieri396513 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesStaphylococcaceaeStaphylococcus
Proteomesi
  • UP000000444 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10002014121 – 395Elongation factor TuAdd BLAST395

Proteomic databases

PRIDEiB9DKV8

Interactioni

Subunit structurei

Monomer.UniRule annotation

Protein-protein interaction databases

STRINGi396513.Sca_0207

Structurei

3D structure databases

ProteinModelPortaliB9DKV8
SMRiB9DKV8
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini10 – 204tr-type GAdd BLAST195

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni19 – 26G1By similarity8
Regioni60 – 64G2By similarity5
Regioni81 – 84G3By similarity4
Regioni136 – 139G4By similarity4
Regioni174 – 176G5By similarity3

Sequence similaritiesi

Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105CGV Bacteria
COG0050 LUCA
HOGENOMiHOG000229290
KOiK02358
OMAiYGHIDCP

Family and domain databases

CDDicd03697 EFTU_II, 1 hit
HAMAPiMF_00118_B EF_Tu_B, 1 hit
InterProiView protein in InterPro
IPR004161 EFTu-like_2
IPR033720 EFTU_2
IPR031157 G_TR_CS
IPR027417 P-loop_NTPase
IPR005225 Small_GTP-bd_dom
IPR000795 TF_GTP-bd_dom
IPR009000 Transl_B-barrel_sf
IPR009001 Transl_elong_EF1A/Init_IF2_C
IPR004541 Transl_elong_EFTu/EF1A_bac/org
IPR004160 Transl_elong_EFTu/EF1A_C
PfamiView protein in Pfam
PF00009 GTP_EFTU, 1 hit
PF03144 GTP_EFTU_D2, 1 hit
PF03143 GTP_EFTU_D3, 1 hit
PRINTSiPR00315 ELONGATNFCT
SUPFAMiSSF50447 SSF50447, 1 hit
SSF50465 SSF50465, 1 hit
SSF52540 SSF52540, 1 hit
TIGRFAMsiTIGR00485 EF-Tu, 1 hit
TIGR00231 small_GTP, 1 hit
PROSITEiView protein in PROSITE
PS00301 G_TR_1, 1 hit
PS51722 G_TR_2, 1 hit

Sequencei

Sequence statusi: Complete.

B9DKV8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAKEKFDRSK EHANIGTIGH VDHGKTTLTA AIATVLAKNG DTVAQSYDMI
60 70 80 90 100
DNAPEEKERG ITINTSHIEY QTDKRHYAHV DCPGHADYVK NMITGAAQMD
110 120 130 140 150
GGILVVSAAD GPMPQTREHI LLSRNVGVPA LVVFLNKADM VDDEELLELV
160 170 180 190 200
EMEVRDLLSE YDFPGDDVPV IVGSALKALE GDAEYEQKIL DLMQAVDDYI
210 220 230 240 250
PTPERDSDKP FMMPVEDVFS ITGRGTVATG RVERGQIKVG EEVEIIGITE
260 270 280 290 300
ESMKTTVTGV EMFRKLLDYA EAGDNIGALL RGVAREDVQR GQVLAAPGSI
310 320 330 340 350
TPHTKFKADV YVLSKDEGGR HTPFFTNYRP QFYFRTTDVT GVVNLPEGTE
360 370 380 390
MVMPGDNVEM TVELIAPIAI EDGTRFSIRE GGRTVGSGVV TEIQQ
Length:395
Mass (Da):43,245
Last modified:March 24, 2009 - v1
Checksum:i48DD113D7BD0A7F5
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AM295250 Genomic DNA Translation: CAL27120.1
RefSeqiWP_012664235.1, NC_012121.1

Genome annotation databases

KEGGisca:SCA_0207

Similar proteinsi

Entry informationi

Entry nameiEFTU_STACT
AccessioniPrimary (citable) accession number: B9DKV8
Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 28, 2009
Last sequence update: March 24, 2009
Last modified: June 20, 2018
This is version 64 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

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