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Protein
Submitted name:

RUN and TBC1 domain-containing protein 1

Gene

RUTBC1

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Names & Taxonomyi

Protein namesi
Submitted name:
RUN and TBC1 domain-containing protein 1Imported
Gene namesi
Name:RUTBC1Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA162403141.

PTM / Processingi

Proteomic databases

PaxDbiB9A6J3.
PRIDEiB9A6J3.

Expressioni

Gene expression databases

BgeeiENSG00000141258.
ExpressionAtlasiB9A6J3. baseline and differential.
GenevisibleiB9A6J3. HS.

Interactioni

Protein-protein interaction databases

IntActiB9A6J3. 1 interactor.
STRINGi9606.ENSP00000268989.

Structurei

3D structure databases

ProteinModelPortaliB9A6J3.
SMRiB9A6J3.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini34 – 191RUNInterPro annotationAdd BLAST158
Domaini566 – 939Rab-GAP TBCInterPro annotationAdd BLAST374

Phylogenomic databases

eggNOGiKOG1648. Eukaryota.
COG5210. LUCA.
HOVERGENiHBG108483.
PhylomeDBiB9A6J3.

Family and domain databases

InterProiIPR000195. Rab-GTPase-TBC_dom.
IPR004012. Run_dom.
[Graphical view]
PfamiPF00566. RabGAP-TBC. 1 hit.
PF02759. RUN. 1 hit.
[Graphical view]
SMARTiSM00593. RUN. 1 hit.
SM00164. TBC. 1 hit.
[Graphical view]
SUPFAMiSSF47923. SSF47923. 3 hits.
PROSITEiPS50826. RUN. 1 hit.
PS50086. TBC_RABGAP. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

B9A6J3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGSAEDAVKE KLLWNVKKEV KQIMEEAVTR KFVHEDSSHI IALCGAVEAC
60 70 80 90 100
LLHQLRRRAA GFLRSDKMAA LFTKVGKTCP VAGEICHKVQ ELQQQAEGRK
110 120 130 140 150
PSGVSQEALR RQGSASGKAP ALSPQALKHV WVRTALIEKV LDKVVQYLAE
160 170 180 190 200
NCSKYYEKEA LLADPVFGPI LASLLVGPCA LEYTKLKTAD HYWTDPSADE
210 220 230 240 250
LVQRHRIRGP PTRQDSPAKR PALGIRKRHS SGSASEDRLA ACARECVESL
260 270 280 290 300
HQNSRTRLLY GKNHVLVQPK EDMEAVPGYL SLHQSAESLT LKWTPNQLMN
310 320 330 340 350
GTLGDSELEK SVYWDYALVV PFSQVVCIHC HQQKSGGTLV LVSQDGIQRP
360 370 380 390 400
PLHFPQGGHL LSFLSCLENG LLPRGQLEPP LWTQQGKGKV FPKLRKRSSI
410 420 430 440 450
RSVDMEEMGT GRATDYVFRI IYPGHRHEHN AGDMIEMQGF GPSLPAWHLE
460 470 480 490 500
PLCSQGSSCL SCSSSSSPHA TPSHCSCIPD RLPLRLLCES MKRQIVSRAF
510 520 530 540 550
YGWLAHCRHL STVRTHLSAL VHHSVIPPDR PPGASAGLTK DVWSKYQKDK
560 570 580 590 600
KNYKELELLR QVYYGGIEHE IRKDVWPFLL GHYKFGMSKK EMEQVDAVVA
610 620 630 640 650
ARYQQVLAEW KACEVVVRQR EREAHPATRT KFSSGSSIDS HVQRLIHRDS
660 670 680 690 700
TISNDVFISV DDLEPPEPQD PEDSRPKPEQ EAGPGTPGTA VVEQQHSVEF
710 720 730 740 750
DSPDSGLPSS RNYSVASGIQ SSLDEGQSVG FEEEDGGGEE GSSGPGPAAH
760 770 780 790 800
TLREPQDPSQ EKPQAGELEA GEELAAVCAA AYTIELLDTV ALNLHRIDKD
810 820 830 840 850
VQRCDRNYWY FTPPNLERLR DVMCSYVWEH LDVGYVQGMC DLLAPLLVTL
860 870 880 890 900
DNDQLAYSCF SHLMKRMSQN FPNGGAMDTH FANMRSLIQI LDSELFELMH
910 920 930 940 950
QNGDYTHFYF CYRWFLLDFK RELLYEDVFA VWEVIWAARH ISSEHFVLFI
960 970 980 990 1000
ALALVEAYRE IIRDNNMDFT DIIKFFNERA EHHDAQEILR IARDLVHKVQ

MLIENK
Length:1,006
Mass (Da):113,285
Last modified:March 24, 2009 - v1
Checksum:i352F6F6D6017B570
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB449878 mRNA. Translation: BAH16621.1.
RefSeqiNP_001091979.1. NM_001098509.1.
UniGeneiHs.513861.

Genome annotation databases

GeneIDi9905.
KEGGihsa:9905.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB449878 mRNA. Translation: BAH16621.1.
RefSeqiNP_001091979.1. NM_001098509.1.
UniGeneiHs.513861.

3D structure databases

ProteinModelPortaliB9A6J3.
SMRiB9A6J3.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

IntActiB9A6J3. 1 interactor.
STRINGi9606.ENSP00000268989.

Proteomic databases

PaxDbiB9A6J3.
PRIDEiB9A6J3.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi9905.
KEGGihsa:9905.

Organism-specific databases

CTDi9905.
PharmGKBiPA162403141.

Phylogenomic databases

eggNOGiKOG1648. Eukaryota.
COG5210. LUCA.
HOVERGENiHBG108483.
PhylomeDBiB9A6J3.

Miscellaneous databases

ChiTaRSiSGSM2. human.
GenomeRNAii9905.

Gene expression databases

BgeeiENSG00000141258.
ExpressionAtlasiB9A6J3. baseline and differential.
GenevisibleiB9A6J3. HS.

Family and domain databases

InterProiIPR000195. Rab-GTPase-TBC_dom.
IPR004012. Run_dom.
[Graphical view]
PfamiPF00566. RabGAP-TBC. 1 hit.
PF02759. RUN. 1 hit.
[Graphical view]
SMARTiSM00593. RUN. 1 hit.
SM00164. TBC. 1 hit.
[Graphical view]
SUPFAMiSSF47923. SSF47923. 3 hits.
PROSITEiPS50826. RUN. 1 hit.
PS50086. TBC_RABGAP. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiB9A6J3_HUMAN
AccessioniPrimary (citable) accession number: B9A6J3
Entry historyi
Integrated into UniProtKB/TrEMBL: March 24, 2009
Last sequence update: March 24, 2009
Last modified: November 30, 2016
This is version 52 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.