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Protein
Submitted name:

Tumor necrosis factor receptor superfamily member 14

Gene

TNFRSF14

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.PROSITE-ProRule annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Tumor necrosis factor receptor superfamily member 14Imported
Gene namesi
Name:TNFRSF14Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 1

Organism-specific databases

EuPathDBiHostDB:ENSG00000157873.17
HGNCiHGNC:11912 TNFRSF14

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000157873

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 38Sequence analysisAdd BLAST38
ChainiPRO_501408578639 – 193Sequence analysisAdd BLAST155

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Disulfide bondi54 ↔ 67PROSITE-ProRule annotation
Disulfide bondi57 ↔ 75PROSITE-ProRule annotation
Disulfide bondi78 ↔ 93PROSITE-ProRule annotation

Keywords - PTMi

Disulfide bondPROSITE-ProRule annotation

Proteomic databases

PeptideAtlasiB9A034

Expressioni

Gene expression databases

BgeeiENSG00000157873

Structurei

3D structure databases

SMRiB9A034
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini41 – 75TNFR-CysInterPro annotationAdd BLAST35
Repeati41 – 75TNFR-CysPROSITE-ProRule annotationAdd BLAST35
Domaini77 – 119TNFR-CysInterPro annotationAdd BLAST43
Repeati77 – 119TNFR-CysPROSITE-ProRule annotationAdd BLAST43

Keywords - Domaini

SignalSequence analysis

Phylogenomic databases

eggNOGiENOG410IX15 Eukaryota
ENOG410ZEC2 LUCA
GeneTreeiENSGT00760000119204
HOGENOMiHOG000065766
HOVERGENiHBG072084

Family and domain databases

CDDicd10582 TNFRSF14, 1 hit
InterProiView protein in InterPro
IPR001368 TNFR/NGFR_Cys_rich_reg
IPR022332 TNFR_14
IPR034031 TNFRSF14/UL144_N
PfamiView protein in Pfam
PF00020 TNFR_c6, 1 hit
PRINTSiPR01965 TNFACTORR14
SMARTiView protein in SMART
SM00208 TNFR, 3 hits
PROSITEiView protein in PROSITE
PS00652 TNFR_NGFR_1, 1 hit
PS50050 TNFR_NGFR_2, 2 hits

Sequencei

Sequence statusi: Complete.

B9A034-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MEPPGDWGPP PWRSTPKTDV LRLVLYLTFL GAPCYAPALP SCKEDEYPVG
60 70 80 90 100
SECCPKCSPG YRVKEACGEL TGTVCEPCPP GTYIAHLNGL SKCLQCQMCD
110 120 130 140 150
PAMGLRASRN CSRTENAVCG CSPGHFCIVQ DGDHCAACRA YATSSPGQRV
160 170 180 190
QKGGTESQDT LCQNCPPGTF SPNGTLEECQ HQTNRAWKSQ TDL
Length:193
Mass (Da):20,753
Last modified:March 3, 2009 - v1
Checksum:iA9AB162A56C20B1F
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL139246 Genomic DNA No translation available.

Genome annotation databases

EnsembliENST00000409119; ENSP00000386859; ENSG00000157873
ENST00000625695; ENSP00000485884; ENSG00000273936
UCSCiuc057bnm.1 human

Similar proteinsi

Entry informationi

Entry nameiB9A034_HUMAN
AccessioniPrimary (citable) accession number: B9A034
Entry historyiIntegrated into UniProtKB/TrEMBL: March 3, 2009
Last sequence update: March 3, 2009
Last modified: April 25, 2018
This is version 75 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
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Main funding by: National Institutes of Health