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Protein
Submitted name:

Cyclic AMP-dependent transcription factor ATF-2

Gene

ATF2

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

LigandMetal-binding, Zinc

Names & Taxonomyi

Protein namesi
Submitted name:
Cyclic AMP-dependent transcription factor ATF-2Imported
Gene namesi
Name:ATF2Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 2

Organism-specific databases

EuPathDBiHostDB:ENSG00000115966.16.
HGNCiHGNC:784. ATF2.

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000115966.

PTM / Processingi

Proteomic databases

MaxQBiB8ZZU6.
PaxDbiB8ZZU6.
PeptideAtlasiB8ZZU6.
PRIDEiB8ZZU6.

Expressioni

Gene expression databases

BgeeiENSG00000115966.
ExpressionAtlasiB8ZZU6. baseline and differential.

Structurei

3D structure databases

ProteinModelPortaliB8ZZU6.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini7 – 31C2H2-typeInterPro annotationAdd BLAST25
Domaini236 – 299BZIPInterPro annotationAdd BLAST64

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili261 – 295Sequence analysisAdd BLAST35

Keywords - Domaini

Coiled coilSequence analysis, Zinc-fingerPROSITE-ProRule annotation

Phylogenomic databases

eggNOGiKOG1414. Eukaryota.
ENOG4111CH5. LUCA.
GeneTreeiENSGT00390000020106.
HOGENOMiHOG000220894.
HOVERGENiHBG004300.

Family and domain databases

InterProiView protein in InterPro
IPR029836. ATF-2.
IPR004827. bZIP.
IPR016378. TF_CRE-BP1-typ.
IPR036236. Znf_C2H2_sf.
IPR013087. Znf_C2H2_type.
PANTHERiPTHR19304:SF9. PTHR19304:SF9. 2 hits.
PfamiView protein in Pfam
PF00170. bZIP_1. 1 hit.
PIRSFiPIRSF003153. ATF2_CRE-BP1. 3 hits.
SMARTiView protein in SMART
SM00338. BRLZ. 1 hit.
SUPFAMiSSF57667. SSF57667. 1 hit.
PROSITEiView protein in PROSITE
PS50217. BZIP. 1 hit.
PS00036. BZIP_BASIC. 1 hit.
PS00028. ZINC_FINGER_C2H2_1. 1 hit.
PS50157. ZINC_FINGER_C2H2_2. 1 hit.

Sequencei

Sequence statusi: Complete.

B8ZZU6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSDDKPFLCT APGCGQRFTN EDHLAVHKHK HEMTLKFGPA RNDSVIVADQ
60 70 80 90 100
TPTPTRFLKN CEEVGLFNEL ASPFENEFKK ASEDDIKKMP LDLSPLATPI
110 120 130 140 150
IRSKIEEPSV VETTHQDSPL PHPESTTSDE KLVRPVTMVP SVPGIPGPSS
160 170 180 190 200
PQPVQSEAKM RLKAALTQQH PPVTNGDTVK GHGSGLVRTQ SEESRPQSLQ
210 220 230 240 250
QPATSTTETP ASPAHTTPQT QSTSGRRRRA ANEDPDEKRR KFLERNRAAA
260 270 280 290 300
SRCRQKRKVW VQSLEKKAED LSSLNGQLQS EVTLLRNEVA QLKQLLLAHK
310 320 330 340 350
DCPVTAMQKK SGYHTADKDD SSEDISVPSS PHTEAIQHSS VSTSNGVSST
360 370 380
SKAEAVATSV LTQMADQSTE PALSQIVMAP SSQSQPSGS
Length:389
Mass (Da):42,324
Last modified:March 3, 2009 - v1
Checksum:iD66AEC416862A533
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC007435 Genomic DNA. No translation available.
AC074291 Genomic DNA. No translation available.
AC096649 Genomic DNA. No translation available.
AC131958 Genomic DNA. No translation available.
KF456745 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENST00000409437; ENSP00000386326; ENSG00000115966.
UCSCiuc061pwq.1. human.

Similar proteinsi

Entry informationi

Entry nameiB8ZZU6_HUMAN
AccessioniPrimary (citable) accession number: B8ZZU6
Entry historyiIntegrated into UniProtKB/TrEMBL: March 3, 2009
Last sequence update: March 3, 2009
Last modified: October 25, 2017
This is version 74 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported