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Protein
Submitted name:

Cyclic AMP-dependent transcription factor ATF-2

Gene

ATF2

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

LigandMetal-binding, Zinc

Names & Taxonomyi

Protein namesi
Submitted name:
Cyclic AMP-dependent transcription factor ATF-2Imported
Gene namesi
Name:ATF2Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 2

Organism-specific databases

EuPathDBiHostDB:ENSG00000115966.16
HGNCiHGNC:784 ATF2

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000115966

PTM / Processingi

Proteomic databases

EPDiB8ZZU6
MaxQBiB8ZZU6
PeptideAtlasiB8ZZU6
PRIDEiB8ZZU6

Expressioni

Gene expression databases

BgeeiENSG00000115966
ExpressionAtlasiB8ZZU6 baseline and differential

Structurei

3D structure databases

ProteinModelPortaliB8ZZU6
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini7 – 31C2H2-typeInterPro annotationAdd BLAST25
Domaini236 – 299BZIPInterPro annotationAdd BLAST64

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili261 – 295Sequence analysisAdd BLAST35

Keywords - Domaini

Coiled coilSequence analysis, Zinc-fingerPROSITE-ProRule annotation

Phylogenomic databases

eggNOGiKOG1414 Eukaryota
ENOG4111CH5 LUCA
GeneTreeiENSGT00390000020106
HOGENOMiHOG000220894
HOVERGENiHBG004300

Family and domain databases

InterProiView protein in InterPro
IPR029836 ATF2
IPR004827 bZIP
IPR016378 TF_CRE-BP1-typ
IPR036236 Znf_C2H2_sf
IPR013087 Znf_C2H2_type
PANTHERiPTHR19304:SF9 PTHR19304:SF9, 2 hits
PfamiView protein in Pfam
PF00170 bZIP_1, 1 hit
PIRSFiPIRSF003153 ATF2_CRE-BP1, 3 hits
SMARTiView protein in SMART
SM00338 BRLZ, 1 hit
SUPFAMiSSF57667 SSF57667, 1 hit
PROSITEiView protein in PROSITE
PS50217 BZIP, 1 hit
PS00036 BZIP_BASIC, 1 hit
PS00028 ZINC_FINGER_C2H2_1, 1 hit
PS50157 ZINC_FINGER_C2H2_2, 1 hit

Sequencei

Sequence statusi: Complete.

B8ZZU6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSDDKPFLCT APGCGQRFTN EDHLAVHKHK HEMTLKFGPA RNDSVIVADQ
60 70 80 90 100
TPTPTRFLKN CEEVGLFNEL ASPFENEFKK ASEDDIKKMP LDLSPLATPI
110 120 130 140 150
IRSKIEEPSV VETTHQDSPL PHPESTTSDE KLVRPVTMVP SVPGIPGPSS
160 170 180 190 200
PQPVQSEAKM RLKAALTQQH PPVTNGDTVK GHGSGLVRTQ SEESRPQSLQ
210 220 230 240 250
QPATSTTETP ASPAHTTPQT QSTSGRRRRA ANEDPDEKRR KFLERNRAAA
260 270 280 290 300
SRCRQKRKVW VQSLEKKAED LSSLNGQLQS EVTLLRNEVA QLKQLLLAHK
310 320 330 340 350
DCPVTAMQKK SGYHTADKDD SSEDISVPSS PHTEAIQHSS VSTSNGVSST
360 370 380
SKAEAVATSV LTQMADQSTE PALSQIVMAP SSQSQPSGS
Length:389
Mass (Da):42,324
Last modified:March 3, 2009 - v1
Checksum:iD66AEC416862A533
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC007435 Genomic DNA No translation available.
AC074291 Genomic DNA No translation available.
AC096649 Genomic DNA No translation available.
AC131958 Genomic DNA No translation available.
KF456745 Genomic DNA No translation available.

Genome annotation databases

EnsembliENST00000409437; ENSP00000386326; ENSG00000115966
UCSCiuc061pwq.1 human

Similar proteinsi

Entry informationi

Entry nameiB8ZZU6_HUMAN
AccessioniPrimary (citable) accession number: B8ZZU6
Entry historyiIntegrated into UniProtKB/TrEMBL: March 3, 2009
Last sequence update: March 3, 2009
Last modified: June 20, 2018
This is version 80 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

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