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Protein
Submitted name:

MAGUK p55 subfamily member 6

Gene

MPP6

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Names & Taxonomyi

Protein namesi
Submitted name:
MAGUK p55 subfamily member 6Imported
Submitted name:
Membrane protein, palmitoylated 6 (MAGUK p55 subfamily member 6), isoform CRA_aImported
Gene namesi
Name:MPP6Imported
ORF Names:hCG_38837Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 7

Organism-specific databases

HGNCiHGNC:18167. MPP6.

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000105926.

PTM / Processingi

Proteomic databases

EPDiB8ZZG1.
MaxQBiB8ZZG1.
PeptideAtlasiB8ZZG1.
PRIDEiB8ZZG1.

Expressioni

Gene expression databases

BgeeiENSG00000105926.
ExpressionAtlasiB8ZZG1. baseline and differential.

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000222644.

Structurei

3D structure databases

ProteinModelPortaliB8ZZG1.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini18 – 97PDZ (DHR)InterPro annotationAdd BLAST80
Domaini103 – 172SH3InterPro annotationAdd BLAST70
Domaini226 – 413Guanylate kinase-likeInterPro annotationAdd BLAST188

Sequence similaritiesi

Contains 1 PDZ (DHR) domain.UniRule annotation

Keywords - Domaini

SH3 domainSAAS annotation

Phylogenomic databases

eggNOGiKOG0609. Eukaryota.
COG0194. LUCA.
GeneTreeiENSGT00760000118866.
HOGENOMiHOG000233034.
HOVERGENiHBG001858.

Family and domain databases

Gene3Di2.30.42.10. 1 hit.
3.40.50.300. 2 hits.
InterProiIPR008145. GK/Ca_channel_bsu.
IPR008144. Guanylate_kin-like_dom.
IPR020590. Guanylate_kinase_CS.
IPR027417. P-loop_NTPase.
IPR001478. PDZ.
IPR011511. SH3_2.
IPR001452. SH3_domain.
[Graphical view]
PfamiPF00625. Guanylate_kin. 1 hit.
PF00595. PDZ. 1 hit.
PF07653. SH3_2. 1 hit.
[Graphical view]
SMARTiSM00072. GuKc. 1 hit.
SM00228. PDZ. 1 hit.
SM00326. SH3. 1 hit.
[Graphical view]
SUPFAMiSSF50044. SSF50044. 1 hit.
SSF50156. SSF50156. 1 hit.
SSF52540. SSF52540. 1 hit.
PROSITEiPS00856. GUANYLATE_KINASE_1. 1 hit.
PS50052. GUANYLATE_KINASE_2. 1 hit.
PS50106. PDZ. 1 hit.
PS50002. SH3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

B8ZZG1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNNSSINNQL LPVDAIRILG IHKRAGEPLG VTFRVENNDL VIARILHGGM
60 70 80 90 100
IDRQGLLHVG DIIKEVNGHE VGNNPKELQE LLKNISGSVT LKILPSYRDT
110 120 130 140 150
ITPQQVFVKC HFDYNPYNDN LIPCKEAGLK FSKGEILQIV NREDPNWWQA
160 170 180 190 200
SHVKEGGSAG LIPSQFLEEK RKAFVRRDWD NSGPFCGTIS SKKKKKMMYL
210 220 230 240 250
TTRNAEFDRH EIQIYEEVAK MPPFQRKTLV LIGAQGVGRR SLKNRFIVLN
260 270 280 290 300
PTRFGTTVPF TSRKPREDEK DGQAYKFVSR SEMEADIKAG KYLEHGEYEG
310 320 330 340 350
NLYGTKIDSI LEVVQTGRTC ILDVNPQALK VLRTSEFMPY VVFIAAPELE
360 370 380 390 400
TLRAMHKAVV DAGITTKLLT DSDLKKTVDE SARIQRAYNH YFDLIIINDN
410 420
LDKAFEKLQT AIEKLRMEPQ WVPISWVY
Length:428
Mass (Da):48,758
Last modified:March 3, 2009 - v1
Checksum:i66B10865BACE56A6
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC003093 Genomic DNA. No translation available.
AC005084 Genomic DNA. No translation available.
CH471073 Genomic DNA. Translation: EAW93808.1.
RefSeqiXP_005249832.1. XM_005249775.4.
UniGeneiHs.533355.
Hs.563501.
Hs.594275.

Genome annotation databases

EnsembliENST00000409761; ENSP00000386262; ENSG00000105926.
GeneIDi51678.
UCSCiuc064ccd.1. human.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC003093 Genomic DNA. No translation available.
AC005084 Genomic DNA. No translation available.
CH471073 Genomic DNA. Translation: EAW93808.1.
RefSeqiXP_005249832.1. XM_005249775.4.
UniGeneiHs.533355.
Hs.563501.
Hs.594275.

3D structure databases

ProteinModelPortaliB8ZZG1.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9606.ENSP00000222644.

Proteomic databases

EPDiB8ZZG1.
MaxQBiB8ZZG1.
PeptideAtlasiB8ZZG1.
PRIDEiB8ZZG1.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000409761; ENSP00000386262; ENSG00000105926.
GeneIDi51678.
UCSCiuc064ccd.1. human.

Organism-specific databases

CTDi51678.
HGNCiHGNC:18167. MPP6.
OpenTargetsiENSG00000105926.
GenAtlasiSearch...

Phylogenomic databases

eggNOGiKOG0609. Eukaryota.
COG0194. LUCA.
GeneTreeiENSGT00760000118866.
HOGENOMiHOG000233034.
HOVERGENiHBG001858.

Miscellaneous databases

ChiTaRSiMPP6. human.
GenomeRNAii51678.

Gene expression databases

BgeeiENSG00000105926.
ExpressionAtlasiB8ZZG1. baseline and differential.

Family and domain databases

Gene3Di2.30.42.10. 1 hit.
3.40.50.300. 2 hits.
InterProiIPR008145. GK/Ca_channel_bsu.
IPR008144. Guanylate_kin-like_dom.
IPR020590. Guanylate_kinase_CS.
IPR027417. P-loop_NTPase.
IPR001478. PDZ.
IPR011511. SH3_2.
IPR001452. SH3_domain.
[Graphical view]
PfamiPF00625. Guanylate_kin. 1 hit.
PF00595. PDZ. 1 hit.
PF07653. SH3_2. 1 hit.
[Graphical view]
SMARTiSM00072. GuKc. 1 hit.
SM00228. PDZ. 1 hit.
SM00326. SH3. 1 hit.
[Graphical view]
SUPFAMiSSF50044. SSF50044. 1 hit.
SSF50156. SSF50156. 1 hit.
SSF52540. SSF52540. 1 hit.
PROSITEiPS00856. GUANYLATE_KINASE_1. 1 hit.
PS50052. GUANYLATE_KINASE_2. 1 hit.
PS50106. PDZ. 1 hit.
PS50002. SH3. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiB8ZZG1_HUMAN
AccessioniPrimary (citable) accession number: B8ZZG1
Entry historyi
Integrated into UniProtKB/TrEMBL: March 3, 2009
Last sequence update: March 3, 2009
Last modified: November 30, 2016
This is version 75 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.