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Protein

Glycerol-3-phosphate dehydrogenase

Gene

glpD

Organism
Mycobacterium leprae (strain Br4923)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

sn-glycerol 3-phosphate + a quinone = glycerone phosphate + a quinol.UniRule annotation

Cofactori

FADUniRule annotation

GO - Molecular functioni

  1. sn-glycerol-3-phosphate:ubiquinone-8 oxidoreductase activity Source: UniProtKB-EC

GO - Biological processi

  1. glycerol-3-phosphate metabolic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

OxidoreductaseUniRule annotationSAAS annotation

Keywords - Ligandi

FlavoproteinUniRule annotation

Enzyme and pathway databases

BioCyciMLEP561304:GJP6-728-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Glycerol-3-phosphate dehydrogenaseUniRule annotation (EC:1.1.5.3UniRule annotation)
Gene namesi
Name:glpDImported
Ordered Locus Names:MLBr00713Imported
OrganismiMycobacterium leprae (strain Br4923)Imported
Taxonomic identifieri561304 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaActinobacteridaeActinomycetalesCorynebacterineaeMycobacteriaceaeMycobacterium
ProteomesiUP000006900: Chromosome

Subcellular locationi

GO - Cellular componenti

  1. glycerol-3-phosphate dehydrogenase complex Source: InterPro
Complete GO annotation...

Interactioni

Protein-protein interaction databases

STRINGi561304.MLBr_00713.

Structurei

3D structure databases

ProteinModelPortaliB8ZUX3.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0578.
KOiK00111.
OMAiPVDQQEQ.
OrthoDBiEOG651SR7.

Family and domain databases

InterProiIPR006076. FAD-dep_OxRdtase.
IPR000447. G3P_DH_FAD-dep.
[Graphical view]
PfamiPF01266. DAO. 1 hit.
[Graphical view]
PRINTSiPR01001. FADG3PDH.
PROSITEiPS00977. FAD_G3PDH_1. 1 hit.
PS00978. FAD_G3PDH_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

B8ZUX3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTDLIQAPES EQTWPASALG PQQRAAAWER FGTEQFDVVV IGGGVVGSGC
60 70 80 90 100
ALDAATRGLK VALVEARDLA SGTSSRSSKM FHGGLRYLEQ LEFGLVREAL
110 120 130 140 150
YERELSLTTL APHLVKPLPF LFPLTKRWWE RPYIAAGIFL YDRLGGAKSV
160 170 180 190 200
PAQKHLTRAG ALRLSPGLKR SSLIGGIRYY DTVVDDARHT LTVARTAAHY
210 220 230 240 250
GAVVRCSTQV VALLREGDRV IGVRVRDSED GAVTEIRGHV VVNATGVWTD
260 270 280 290 300
EIQALSKQRG RFQVRVSKGV HVVVPRDRIV SDVAMILRTK KSVMFIIPWG
310 320 330 340 350
NHWIIGTTDT DWNLDLAHPA ATKADIDYIL QTVNTVLATP LTHADIDGVY
360 370 380 390 400
AGLRPLLAGE SDDTSKLTRE HAVAVPVAGL VAIAGGKYTT YRVMAADAID
410 420 430 440 450
AAVAFVPARV APSITEKVGL LGADGYFALI NQVEHVAALQ GLHPYRVRHL
460 470 480 490 500
LDRYGALIGD VLALAAEAPD LLSPIQEAPG YLKVEARYAV TAEGALHLED
510 520 530 540 550
ILARRMRVSI EYPHRGVACA REVADVVAPV LGWTAEDIDR EVATYNARVE
560 570 580
AEVLSQAQPD DVSADMLRAS APEARTKIIE PVSLT
Length:585
Mass (Da):63,373
Last modified:March 3, 2009 - v1
Checksum:i4B468DD09C1C70F8
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
FM211192 Genomic DNA. Translation: CAR70807.1.
RefSeqiYP_002503195.1. NC_011896.1.

Genome annotation databases

EnsemblBacteriaiCAR70807; CAR70807; MLBr00713.
GeneIDi7325405.
KEGGimlb:MLBr_00713.
PATRICi18042116. VBIMycLep121698_1289.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
FM211192 Genomic DNA. Translation: CAR70807.1.
RefSeqiYP_002503195.1. NC_011896.1.

3D structure databases

ProteinModelPortaliB8ZUX3.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi561304.MLBr_00713.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiCAR70807; CAR70807; MLBr00713.
GeneIDi7325405.
KEGGimlb:MLBr_00713.
PATRICi18042116. VBIMycLep121698_1289.

Phylogenomic databases

eggNOGiCOG0578.
KOiK00111.
OMAiPVDQQEQ.
OrthoDBiEOG651SR7.

Enzyme and pathway databases

BioCyciMLEP561304:GJP6-728-MONOMER.

Family and domain databases

InterProiIPR006076. FAD-dep_OxRdtase.
IPR000447. G3P_DH_FAD-dep.
[Graphical view]
PfamiPF01266. DAO. 1 hit.
[Graphical view]
PRINTSiPR01001. FADG3PDH.
PROSITEiPS00977. FAD_G3PDH_1. 1 hit.
PS00978. FAD_G3PDH_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Br4923Imported.

Entry informationi

Entry nameiB8ZUX3_MYCLB
AccessioniPrimary (citable) accession number: B8ZUX3
Entry historyi
Integrated into UniProtKB/TrEMBL: March 3, 2009
Last sequence update: March 3, 2009
Last modified: February 4, 2015
This is version 35 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.