Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

B8ZUP9

- B8ZUP9_MYCLB

UniProt

B8ZUP9 - B8ZUP9_MYCLB

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein

Phosphoenolpyruvate carboxylase

Gene

ppc

Organism
Mycobacterium leprae (strain Br4923)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.UniRule annotation

Catalytic activityi

Phosphate + oxaloacetate = H2O + phosphoenolpyruvate + HCO3-.UniRule annotationSAAS annotation

Cofactori

Note: Magnesium.UniRule annotationSAAS annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei161 – 1611UniRule annotation
Active sitei593 – 5931UniRule annotation

GO - Molecular functioni

  1. magnesium ion binding Source: UniProtKB-HAMAP
  2. phosphoenolpyruvate carboxylase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. carbon fixation Source: UniProtKB-HAMAP
  2. oxaloacetate metabolic process Source: UniProtKB-HAMAP
  3. tricarboxylic acid cycle Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

LyaseUniRule annotationSAAS annotation

Keywords - Biological processi

Carbon dioxide fixationUniRule annotationSAAS annotation

Keywords - Ligandi

MagnesiumUniRule annotationSAAS annotation, PyruvateImported

Enzyme and pathway databases

BioCyciMLEP561304:GJP6-590-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphoenolpyruvate carboxylaseUniRule annotation (EC:4.1.1.31UniRule annotation)
Short name:
PEPCUniRule annotation
Short name:
PEPCaseUniRule annotation
Gene namesi
Name:ppcUniRule annotationImported
Ordered Locus Names:MLBr00578Imported
OrganismiMycobacterium leprae (strain Br4923)Imported
Taxonomic identifieri561304 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaActinobacteridaeActinomycetalesCorynebacterineaeMycobacteriaceaeMycobacterium
ProteomesiUP000006900: Chromosome

Interactioni

Subunit structurei

Homotetramer.UniRule annotation

Protein-protein interaction databases

STRINGi561304.MLBr_00578.

Structurei

3D structure databases

ProteinModelPortaliB8ZUP9.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the PEPCase type 1 family.UniRule annotation

Phylogenomic databases

eggNOGiCOG2352.
KOiK01595.
OMAiHERTIAM.
OrthoDBiEOG6TJ7T8.

Family and domain databases

HAMAPiMF_00595. PEPcase_type1.
InterProiIPR021135. PEP_COase.
IPR018129. PEP_COase_AS.
IPR022805. PEP_COase_bac/pln-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view]
PfamiPF00311. PEPcase. 1 hit.
[Graphical view]
PRINTSiPR00150. PEPCARBXLASE.
SUPFAMiSSF51621. SSF51621. 1 hit.
PROSITEiPS00781. PEPCASE_1. 1 hit.
PS00393. PEPCASE_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

B8ZUP9-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MVEFSDAILE PIGAVQRTRV GREATEPMRA DIRLLGTILG DTLREQNGDE
60 70 80 90 100
VFDLVERVRV ESFRVRRSEI DRADMARMFS GLDIHLAIPI IRAFSHFALL
110 120 130 140 150
ANVAEDIHRE RRRHIHLDAG EPLRDSSLAA TYAKLDLAKL DSATVADALT
160 170 180 190 200
GAVVSPVITA HPTETRRRTV FVTQRRITEL MRLHAEGHTE TADGRSIERE
210 220 230 240 250
LRRQILTLWQ TALIRLARLQ ISDEIDVGLR YYSAALFHVI PQVNSEVRNA
260 270 280 290 300
LRARWPDAEL LSGPILQPGS WIGGDRDGNP NVTADVVRRA TGSAAYTVVA
310 320 330 340 350
HYLAELTHLE QELSMSARLI TVTPELATLA ASCQDAACAD EPYRRALRVI
360 370 380 390 400
RGRLSSTAAH ILDQQPPNQL GLGLPPYSTP AELCADLDTI EASLCTHGAA
410 420 430 440 450
LLADDRLALL REGVGVFGFH LCGLDMRQNS DVHEEVVAEL LAWAGMHQDY
460 470 480 490 500
SSLPEDQRVK LLVAELGNRR PLVGDRAQLS DLARGELAVL AAAAHAVELY
510 520 530 540 550
GSAAVPNYII SMCQSVSDVL EVAILLKETG LLDASGSQPY CPVGISPLFE
560 570 580 590 600
TIDDLHNGAA ILHAMLELPL YRTLVAARGN WQEVMLGYSD SNKDGGYLAA
610 620 630 640 650
NWAVYRAELA LVDVARKTGI RLRLFHGRGG TVGRGGGPSY QAILAQPPGA
660 670 680 690 700
VNGSLRLTEQ GEVIAAKYAE PQIARRNLES LVAATLESTL LDVEGLGDAA
710 720 730 740 750
ESAYAILDEV AGLARRSYAE LVNTPGFVDY FQASTPVSEI GSLNIGNRPT
760 770 780 790 800
SRKPTTSIAD LRAIPWVLAW SQSRVMLPGW YGTGSAFQQW VAAGPESESQ
810 820 830 840 850
RVEMLHDLYQ RWPFFRSVLS NMAQVLAKSD LGLAARYAEL VVDEALRRRV
860 870 880 890 900
FDKIADEHRR TIAIHKLITG HDDLLADNPA LARSVFNRFP YLEPLNHLQV
910 920 930
ELLRRYRSGH DDEMVQRGIL LTMNGLASAL RNSG
Length:934
Mass (Da):102,516
Last modified:March 3, 2009 - v1
Checksum:i3EE8FD762EC45180
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
FM211192 Genomic DNA. Translation: CAR70671.1.
RefSeqiYP_002503121.1. NC_011896.1.

Genome annotation databases

EnsemblBacteriaiCAR70671; CAR70671; MLBr00578.
GeneIDi7326942.
KEGGimlb:MLBr_00578.
PATRICi18041548. VBIMycLep121698_1005.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
FM211192 Genomic DNA. Translation: CAR70671.1 .
RefSeqi YP_002503121.1. NC_011896.1.

3D structure databases

ProteinModelPortali B8ZUP9.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 561304.MLBr_00578.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai CAR70671 ; CAR70671 ; MLBr00578 .
GeneIDi 7326942.
KEGGi mlb:MLBr_00578.
PATRICi 18041548. VBIMycLep121698_1005.

Phylogenomic databases

eggNOGi COG2352.
KOi K01595.
OMAi HERTIAM.
OrthoDBi EOG6TJ7T8.

Enzyme and pathway databases

BioCyci MLEP561304:GJP6-590-MONOMER.

Family and domain databases

HAMAPi MF_00595. PEPcase_type1.
InterProi IPR021135. PEP_COase.
IPR018129. PEP_COase_AS.
IPR022805. PEP_COase_bac/pln-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view ]
Pfami PF00311. PEPcase. 1 hit.
[Graphical view ]
PRINTSi PR00150. PEPCARBXLASE.
SUPFAMi SSF51621. SSF51621. 1 hit.
PROSITEi PS00781. PEPCASE_1. 1 hit.
PS00393. PEPCASE_2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Br4923Imported.

Entry informationi

Entry nameiB8ZUP9_MYCLB
AccessioniPrimary (citable) accession number: B8ZUP9
Entry historyi
Integrated into UniProtKB/TrEMBL: March 3, 2009
Last sequence update: March 3, 2009
Last modified: November 26, 2014
This is version 39 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

External Data

Dasty 3