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B8ZUP9

- B8ZUP9_MYCLB

UniProt

B8ZUP9 - B8ZUP9_MYCLB

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Protein
Phosphoenolpyruvate carboxylase
Gene
ppc, MLBr00578
Organism
Mycobacterium leprae (strain Br4923)
Status
Unreviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle By similarity.UniRule annotation

Catalytic activityi

Phosphate + oxaloacetate = H2O + phosphoenolpyruvate + HCO3-.UniRule annotationSAAS annotations

Cofactori

Magnesium By similarity.UniRule annotationSAAS annotations

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei161 – 1611 By similarityUniRule annotation
Active sitei593 – 5931 By similarityUniRule annotation

GO - Molecular functioni

  1. magnesium ion binding Source: UniProtKB-HAMAP
  2. phosphoenolpyruvate carboxylase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. carbon fixation Source: UniProtKB-HAMAP
  2. oxaloacetate metabolic process Source: UniProtKB-HAMAP
  3. tricarboxylic acid cycle Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

LyaseUniRule annotationSAAS annotationsImported

Keywords - Biological processi

Carbon dioxide fixationUniRule annotationSAAS annotations

Keywords - Ligandi

MagnesiumUniRule annotationSAAS annotations, PyruvateImported

Enzyme and pathway databases

BioCyciMLEP561304:GJP6-590-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphoenolpyruvate carboxylaseUniRule annotation (EC:4.1.1.31UniRule annotation)
Short name:
PEPCUniRule annotation
Short name:
PEPCaseUniRule annotation
Gene namesi
Name:ppcUniRule annotationImported
Ordered Locus Names:MLBr00578Imported
OrganismiMycobacterium leprae (strain Br4923)Imported
Taxonomic identifieri561304 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaActinobacteridaeActinomycetalesCorynebacterineaeMycobacteriaceaeMycobacterium
ProteomesiUP000006900: Chromosome

Interactioni

Subunit structurei

Homotetramer By similarity.UniRule annotation

Protein-protein interaction databases

STRINGi561304.MLBr_00578.

Structurei

3D structure databases

ProteinModelPortaliB8ZUP9.

Family & Domainsi

Sequence similaritiesi

Belongs to the PEPCase type 1 family.UniRule annotation

Phylogenomic databases

eggNOGiCOG2352.
KOiK01595.
OMAiHERTIAM.
OrthoDBiEOG6TJ7T8.

Family and domain databases

HAMAPiMF_00595. PEPcase_type1.
InterProiIPR021135. PEP_COase.
IPR018129. PEP_COase_AS.
IPR022805. PEP_COase_bac/pln-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view]
PfamiPF00311. PEPcase. 1 hit.
[Graphical view]
PRINTSiPR00150. PEPCARBXLASE.
SUPFAMiSSF51621. SSF51621. 1 hit.
PROSITEiPS00781. PEPCASE_1. 1 hit.
PS00393. PEPCASE_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

B8ZUP9-1 [UniParc]FASTAAdd to Basket

« Hide

MVEFSDAILE PIGAVQRTRV GREATEPMRA DIRLLGTILG DTLREQNGDE    50
VFDLVERVRV ESFRVRRSEI DRADMARMFS GLDIHLAIPI IRAFSHFALL 100
ANVAEDIHRE RRRHIHLDAG EPLRDSSLAA TYAKLDLAKL DSATVADALT 150
GAVVSPVITA HPTETRRRTV FVTQRRITEL MRLHAEGHTE TADGRSIERE 200
LRRQILTLWQ TALIRLARLQ ISDEIDVGLR YYSAALFHVI PQVNSEVRNA 250
LRARWPDAEL LSGPILQPGS WIGGDRDGNP NVTADVVRRA TGSAAYTVVA 300
HYLAELTHLE QELSMSARLI TVTPELATLA ASCQDAACAD EPYRRALRVI 350
RGRLSSTAAH ILDQQPPNQL GLGLPPYSTP AELCADLDTI EASLCTHGAA 400
LLADDRLALL REGVGVFGFH LCGLDMRQNS DVHEEVVAEL LAWAGMHQDY 450
SSLPEDQRVK LLVAELGNRR PLVGDRAQLS DLARGELAVL AAAAHAVELY 500
GSAAVPNYII SMCQSVSDVL EVAILLKETG LLDASGSQPY CPVGISPLFE 550
TIDDLHNGAA ILHAMLELPL YRTLVAARGN WQEVMLGYSD SNKDGGYLAA 600
NWAVYRAELA LVDVARKTGI RLRLFHGRGG TVGRGGGPSY QAILAQPPGA 650
VNGSLRLTEQ GEVIAAKYAE PQIARRNLES LVAATLESTL LDVEGLGDAA 700
ESAYAILDEV AGLARRSYAE LVNTPGFVDY FQASTPVSEI GSLNIGNRPT 750
SRKPTTSIAD LRAIPWVLAW SQSRVMLPGW YGTGSAFQQW VAAGPESESQ 800
RVEMLHDLYQ RWPFFRSVLS NMAQVLAKSD LGLAARYAEL VVDEALRRRV 850
FDKIADEHRR TIAIHKLITG HDDLLADNPA LARSVFNRFP YLEPLNHLQV 900
ELLRRYRSGH DDEMVQRGIL LTMNGLASAL RNSG 934
Length:934
Mass (Da):102,516
Last modified:March 3, 2009 - v1
Checksum:i3EE8FD762EC45180
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
FM211192 Genomic DNA. Translation: CAR70671.1.
RefSeqiYP_002503121.1. NC_011896.1.

Genome annotation databases

EnsemblBacteriaiCAR70671; CAR70671; MLBr00578.
GeneIDi7326942.
KEGGimlb:MLBr_00578.
PATRICi18041548. VBIMycLep121698_1005.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
FM211192 Genomic DNA. Translation: CAR70671.1 .
RefSeqi YP_002503121.1. NC_011896.1.

3D structure databases

ProteinModelPortali B8ZUP9.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 561304.MLBr_00578.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai CAR70671 ; CAR70671 ; MLBr00578 .
GeneIDi 7326942.
KEGGi mlb:MLBr_00578.
PATRICi 18041548. VBIMycLep121698_1005.

Phylogenomic databases

eggNOGi COG2352.
KOi K01595.
OMAi HERTIAM.
OrthoDBi EOG6TJ7T8.

Enzyme and pathway databases

BioCyci MLEP561304:GJP6-590-MONOMER.

Family and domain databases

HAMAPi MF_00595. PEPcase_type1.
InterProi IPR021135. PEP_COase.
IPR018129. PEP_COase_AS.
IPR022805. PEP_COase_bac/pln-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view ]
Pfami PF00311. PEPcase. 1 hit.
[Graphical view ]
PRINTSi PR00150. PEPCARBXLASE.
SUPFAMi SSF51621. SSF51621. 1 hit.
PROSITEi PS00781. PEPCASE_1. 1 hit.
PS00393. PEPCASE_2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Br4923.

Entry informationi

Entry nameiB8ZUP9_MYCLB
AccessioniPrimary (citable) accession number: B8ZUP9
Entry historyi
Integrated into UniProtKB/TrEMBL: March 3, 2009
Last sequence update: March 3, 2009
Last modified: June 11, 2014
This is version 36 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome

External Data

Dasty 3

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