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B8ZUC6 (B8ZUC6_MYCLB) Unreviewed, UniProtKB/TrEMBL

Last modified January 25, 2012. Version 21. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Alanine racemase HAMAP MF_01201 RuleBase RU000608
EC=5.1.1.1 HAMAP MF_01201 RuleBase RU000608
Gene names
Name:alr HAMAP MF_01201 EMBL CAR70468.1
Ordered Locus Names:MLBr00375
OrganismMycobacterium leprae (strain Br4923) [Complete proteome] [HAMAP]
Taxonomic identifier561304 [NCBI]
Taxonomic lineageBacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Corynebacterineae › Mycobacteriaceae › Mycobacterium

Protein attributes

Sequence length388 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Provides the D-alanine required for cell wall biosynthesis By similarity. HAMAP MF_01201

Catalytic activity

L-alanine = D-alanine. HAMAP MF_01201 RuleBase RU000608 SAAS SAAS009006

Cofactor

Pyridoxal phosphate By similarity. HAMAP MF_01201 RuleBase RU000608 SAAS SAAS009006

Pathway

Amino-acid biosynthesis; D-alanine biosynthesis; D-alanine from L-alanine: step 1/1. HAMAP MF_01201 SAAS SAAS009006 RuleBase RU004247

Cell wall biogenesis; peptidoglycan biosynthesis. HAMAP MF_01201

Sequence similarities

Belongs to the alanine racemase family. HAMAP MF_01201 RuleBase RU004188

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Active site441Proton acceptor; specific for D-alanine By similarity HAMAP MF_01201
Active site2731Proton acceptor; specific for L-alanine By similarity HAMAP MF_01201

Amino acid modifications

Modified residue441N6-(pyridoxal phosphate)lysine By similarity HAMAP MF_01201

Sequences

Sequence LengthMass (Da)Tools
B8ZUC6 [UniParc].

Last modified March 3, 2009. Version 1.
Checksum: E4075B683D00D196

FASTA38841,083
        10         20         30         40         50         60 
MAVTPISLRP GVLAEAVVDL GAIDYNVRVL REHAGMAQLM VVLKADAYGH GATQVALAAL 

        70         80         90        100        110        120 
AAGAAELGVA TVDEALALRA DGISAPVLAW LHPPGIDFGP ALLADVQIAV SSVRQLDELL 

       130        140        150        160        170        180 
DAVRRTGRTA TVTVKADTGL NRNGVVTDQY PAMLTALQRA VVEDAVRLRG LMSHLVYADQ 

       190        200        210        220        230        240 
PDNPSNDVQG KRFAALLAQA HEQGLRFEVA HLSNSSATMS RPDLAYDLVR PGIAVYGLSP 

       250        260        270        280        290        300 
VPSRGDMGLI PAMTVKCAVA MVKSIRAGEG VSYGHDWIAQ HDTNLALLPV GYADGVFRSL 

       310        320        330        340        350        360 
GGRLDVLING KRRPGVGRIC MDQFVVDLGP GPIDVAEGDE AILFGPGARG EPTAQDWADL 

       370        380 
LGTIHYEVVT SLRGRITRTY REAQTVDR

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		FM211192 Genomic DNA. Translation: CAR70468.1.
RefSeqYP_002502998.1. NC_011896.1.

3D structure databases

ProteinModelPortalB8ZUC6.
SMRB8ZUC6. Positions 13-383.
ModBaseSearch...

Protein-protein interaction databases

STRINGB8ZUC6.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaEBMYCT00000086398; EBMYCP00000082708; EBMYCG00000087238.
GeneID7325327.
GenomeReviewsGene locus MLBr00375 in contig FM211192_GR.
PATRIC18040798. VBIMycLep121698_0632.

Organism-specific databases

CMRSearch...

Phylogenomic databases

GeneTreeEBGT00050000016627.
HOGENOMHBG712172.
OMAEGTPVWV.
ProtClustDBPRK00053.

Family and domain databases

HAMAPMF_01201. Ala_racemase.
[Tree]
InterProIPR000821. Ala_racemase.
IPR009006. Ala_racemase/Decarboxylase_C.
IPR011079. Ala_racemase_C.
IPR001608. Ala_racemase_N.
IPR020622. Ala_racemase_pyridoxalP-BS.
[Graphical view]
Gene3DG3DSA:2.40.37.10. Ala_racemase/Decarboxylase_C. 1 hit.
PfamPF00842. Ala_racemase_C. 1 hit.
PF01168. Ala_racemase_N. 1 hit.
[Graphical view]
PRINTSPR00992. ALARACEMASE.
SMARTSM01005. Ala_racemase_C. 1 hit.
[Graphical view]
SUPFAMSSF50621. Racem_decarbox_C. 1 hit.
TIGRFAMsTIGR00492. Alr. 1 hit.
PROSITEPS00395. ALANINE_RACEMASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameB8ZUC6_MYCLB
AccessionPrimary (citable) accession number: B8ZUC6
Entry history
Integrated into UniProtKB/TrEMBL: March 3, 2009
Last sequence update: March 3, 2009
Last modified: January 25, 2012
This is version 21 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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