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B8ZTC3

- DCD_MYCLB

UniProt

B8ZTC3 - DCD_MYCLB

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Protein

Deoxycytidine triphosphate deaminase

Gene

dcd

Organism
Mycobacterium leprae (strain Br4923)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Catalytic activityi

dCTP + H2O = dUTP + NH3.UniRule annotation

Pathwayi

GO - Molecular functioni

  1. dCTP deaminase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. dUMP biosynthetic process Source: UniProtKB-UniPathway
  2. dUTP biosynthetic process Source: InterPro
  3. pyrimidine ribonucleotide biosynthetic process Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Hydrolase

Keywords - Biological processi

Nucleotide metabolism

Enzyme and pathway databases

BioCyciMLEP561304:GJP6-2562-MONOMER.
UniPathwayiUPA00610; UER00665.

Names & Taxonomyi

Protein namesi
Recommended name:
Deoxycytidine triphosphate deaminaseUniRule annotation (EC:3.5.4.13UniRule annotation)
Short name:
dCTP deaminaseUniRule annotation
Gene namesi
Name:dcdUniRule annotation
Ordered Locus Names:MLBr02507
OrganismiMycobacterium leprae (strain Br4923)
Taxonomic identifieri561304 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaActinobacteridaeActinomycetalesCorynebacterineaeMycobacteriaceaeMycobacterium
ProteomesiUP000006900: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 190190Deoxycytidine triphosphate deaminasePRO_1000123153Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi561304.MLBr_02507.

Structurei

3D structure databases

ProteinModelPortaliB8ZTC3.
SMRiB8ZTC3. Positions 1-189.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the dCTP deaminase family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0717.
KOiK01494.
OMAiNFHRTEI.
OrthoDBiEOG67DPKR.

Family and domain databases

Gene3Di2.70.40.10. 1 hit.
HAMAPiMF_00146. dCTP_deaminase.
InterProiIPR011962. dCTP_deam.
IPR029054. dUTPase-like.
IPR008180. dUTPase/dCTP_deaminase.
[Graphical view]
PfamiPF00692. dUTPase. 1 hit.
[Graphical view]
SUPFAMiSSF51283. SSF51283. 1 hit.
TIGRFAMsiTIGR02274. dCTP_deam. 1 hit.

Sequencei

Sequence statusi: Complete.

B8ZTC3-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MLLSDRDLRA EITAGRFSID PFDDTLVQPS SIDVRLDCMF RVFNNTRYTH
60 70 80 90 100
IDPARQQDEL TSLVELVDGE PFVLHPGGFV LGSTLELFTL PEDLAGRLEG
110 120 130 140 150
KSSLGRLGLL THSTAGFIDP GFCGHITLEL SNVANLPITL WPGMKIGQLC
160 170 180 190
VLRLTSPAEH PYGSASAGSK YQGQRGPTPS RSYENFIKNT
Length:190
Mass (Da):20,821
Last modified:March 3, 2009 - v1
Checksum:i1CA936700500B6FA
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
FM211192 Genomic DNA. Translation: CAR72606.1.
RefSeqiYP_002504249.1. NC_011896.1.

Genome annotation databases

EnsemblBacteriaiCAR72606; CAR72606; MLBr02507.
GeneIDi7327296.
KEGGimlb:MLBr_02507.
PATRICi18049279. VBIMycLep121698_4839.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
FM211192 Genomic DNA. Translation: CAR72606.1 .
RefSeqi YP_002504249.1. NC_011896.1.

3D structure databases

ProteinModelPortali B8ZTC3.
SMRi B8ZTC3. Positions 1-189.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 561304.MLBr_02507.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai CAR72606 ; CAR72606 ; MLBr02507 .
GeneIDi 7327296.
KEGGi mlb:MLBr_02507.
PATRICi 18049279. VBIMycLep121698_4839.

Phylogenomic databases

eggNOGi COG0717.
KOi K01494.
OMAi NFHRTEI.
OrthoDBi EOG67DPKR.

Enzyme and pathway databases

UniPathwayi UPA00610 ; UER00665 .
BioCyci MLEP561304:GJP6-2562-MONOMER.

Family and domain databases

Gene3Di 2.70.40.10. 1 hit.
HAMAPi MF_00146. dCTP_deaminase.
InterProi IPR011962. dCTP_deam.
IPR029054. dUTPase-like.
IPR008180. dUTPase/dCTP_deaminase.
[Graphical view ]
Pfami PF00692. dUTPase. 1 hit.
[Graphical view ]
SUPFAMi SSF51283. SSF51283. 1 hit.
TIGRFAMsi TIGR02274. dCTP_deam. 1 hit.
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Br4923.

Entry informationi

Entry nameiDCD_MYCLB
AccessioniPrimary (citable) accession number: B8ZTC3
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 28, 2009
Last sequence update: March 3, 2009
Last modified: November 26, 2014
This is version 40 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3