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B8ZTC3 (DCD_MYCLB) Reviewed, UniProtKB/Swiss-Prot

Last modified May 1, 2013. Version 31. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Deoxycytidine triphosphate deaminase
Short name=dCTP deaminase
EC=3.5.4.13
Gene names
Name:dcd
Ordered Locus Names:MLBr02507
OrganismMycobacterium leprae (strain Br4923) [Complete proteome] [HAMAP]
Taxonomic identifier561304 [NCBI]
Taxonomic lineageBacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Corynebacterineae › Mycobacteriaceae › Mycobacterium ›

Protein attributes

Sequence length190 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

dCTP + H2O = dUTP + NH3. HAMAP-Rule MF_00146

Pathway

Pyrimidine metabolism; dUMP biosynthesis; dUMP from dCTP (dUTP route): step 1/2. HAMAP-Rule MF_00146

Sequence similarities

Belongs to the dCTP deaminase family.

Ontologies

Keywords
   Biological processNucleotide metabolism
   Molecular functionHydrolase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processdUMP biosynthetic process

Inferred from electronic annotation. Source: UniProtKB-UniPathway

dUTP biosynthetic process

Inferred from electronic annotation. Source: InterPro

pyrimidine ribonucleotide biosynthetic process

Inferred from electronic annotation. Source: HAMAP

   Molecular_functiondCTP deaminase activity

Inferred from electronic annotation. Source: HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 190190Deoxycytidine triphosphate deaminase HAMAP-Rule MF_00146
PRO_1000123153

Sequences

Sequence LengthMass (Da)Tools
B8ZTC3 [UniParc].

Last modified March 3, 2009. Version 1.
Checksum: 1CA936700500B6FA

FASTA19020,821
        10         20         30         40         50         60 
MLLSDRDLRA EITAGRFSID PFDDTLVQPS SIDVRLDCMF RVFNNTRYTH IDPARQQDEL 

        70         80         90        100        110        120 
TSLVELVDGE PFVLHPGGFV LGSTLELFTL PEDLAGRLEG KSSLGRLGLL THSTAGFIDP 

       130        140        150        160        170        180 
GFCGHITLEL SNVANLPITL WPGMKIGQLC VLRLTSPAEH PYGSASAGSK YQGQRGPTPS 

       190 
RSYENFIKNT

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		FM211192 Genomic DNA. Translation: CAR72606.1.
RefSeqYP_002504249.1. NC_011896.1.

3D structure databases

ProteinModelPortalB8ZTC3.
SMRB8ZTC3. Positions 1-189.
ModBaseSearch...

Protein-protein interaction databases

STRING561304.MLBr_02507.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaCAR72606; CAR72606; MLBr02507.
GeneID7327296.
KEGGmlb:MLBr_02507.
PATRIC18049279. VBIMycLep121698_4839.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0717.
KOK01494.
OMARSVLTVC.
ProtClustDBPRK00416.

Enzyme and pathway databases

BioCycMLEP561304:GJP6-2562-MONOMER.
UniPathwayUPA00610; UER00665.

Family and domain databases

HAMAPMF_00146. dCTP_deaminase.
InterProIPR011962. dCTP_deam.
IPR008180. dUTP_pyroPase.
[Graphical view]
PfamPF00692. dUTPase. 1 hit.
[Graphical view]
TIGRFAMsTIGR02274. dCTP_deam. 1 hit.
ProtoNetSearch...

Entry information

Entry nameDCD_MYCLB
AccessionPrimary (citable) accession number: B8ZTC3
Entry history
Integrated into UniProtKB/Swiss-Prot: July 28, 2009
Last sequence update: March 3, 2009
Last modified: May 1, 2013
This is version 31 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

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