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B8ZRZ6 (B8ZRZ6_MYCLB) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 22. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Phosphopantetheine adenylyltransferase HAMAP MF_00151
EC=2.7.7.3 HAMAP MF_00151
Alternative name(s):
Dephospho-CoA pyrophosphorylase HAMAP MF_00151
Pantetheine-phosphate adenylyltransferase HAMAP MF_00151
Gene names
Name:coaD HAMAP MF_00151 EMBL CAR71758.1
Ordered Locus Names:MLBr01663
OrganismMycobacterium leprae (strain Br4923) [Complete proteome] [HAMAP]
Taxonomic identifier561304 [NCBI]
Taxonomic lineageBacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Corynebacterineae › Mycobacteriaceae › Mycobacterium

Protein attributes

Sequence length157 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate By similarity. HAMAP MF_00151

Catalytic activity

ATP + pantetheine 4'-phosphate = diphosphate + 3'-dephospho-CoA. HAMAP MF_00151

Pathway

Cofactor biosynthesis; coenzyme A biosynthesis; CoA from (R)-pantothenate: step 4/5. HAMAP MF_00151

Subunit structure

Homohexamer By similarity. HAMAP MF_00151

Subcellular location

Cytoplasm By similarity HAMAP MF_00151.

Sequence similarities

Belongs to the bacterial CoaD family. HAMAP MF_00151

Sequences

Sequence LengthMass (Da)Tools
B8ZRZ6 [UniParc].

Last modified March 3, 2009. Version 1.
Checksum: 952E092DA5D37DDF

FASTA15717,223
        10         20         30         40         50         60 
MVCPGSFDPV TLGHIDVFER AAAQFDEVVV AILINPVKKG MFDLDERIAM INESTMHLPN 

        70         80         90        100        110        120 
LRVEAGEGLV VALVRSRGMT AIVKGLRTGV DFEYELQMAQ MNKHIAGVDT FFVATAPRYS 

       130        140        150 
FVSSSLVKEV AMLGGDVSEL LPESVNRRFR EKMSGTS

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		FM211192 Genomic DNA. Translation: CAR71758.1.
RefSeqYP_002503773.1. NC_011896.1.

3D structure databases

ProteinModelPortalB8ZRZ6.
ModBaseSearch...

Protein-protein interaction databases

STRINGB8ZRZ6.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaEBMYCT00000086794; EBMYCP00000082981; EBMYCG00000086247.
GeneID7326777.
GenomeReviewsGene locus MLBr01663 in contig FM211192_GR.
PATRIC18045862. VBIMycLep121698_3147.

Organism-specific databases

CMRSearch...

Phylogenomic databases

GeneTreeEBGT00050000017247.
HOGENOMHBG288308.
OMAAMSDFEY.
ProtClustDBPRK00168.

Family and domain databases

HAMAPMF_00151. PPAT_bact.
[Tree]
InterProIPR004821. Cyt_trans-rel.
IPR004820. Cytidylyltransf.
IPR001980. LPS_biosynth.
IPR014729. Rossmann-like_a/b/a_fold.
[Graphical view]
Gene3DG3DSA:3.40.50.620. Rossmann-like_a/b/a_fold. 1 hit.
PfamPF01467. CTP_transf_2. 1 hit.
[Graphical view]
PRINTSPR01020. LPSBIOSNTHSS.
TIGRFAMsTIGR01510. CoaD_prev_kdtB. 1 hit.
TIGR00125. Cyt_tran_rel. 1 hit.
ProtoNetSearch...

Entry information

Entry nameB8ZRZ6_MYCLB
AccessionPrimary (citable) accession number: B8ZRZ6
Entry history
Integrated into UniProtKB/TrEMBL: March 3, 2009
Last sequence update: March 3, 2009
Last modified: December 14, 2011
This is version 22 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
to top of pageNames·Attributes·General annotation·Ontologies·Sequences·References·Cross-refs·Entry info