B8ZRW7 (RIMM_MYCLB) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Ribosome maturation factor rimM

Gene names

Name:	rimM
Ordered Locus Names:	MLBr01616

Organism

Mycobacterium leprae (strain Br4923) [Complete proteome] [HAMAP]

Taxonomic identifier

561304 [NCBI]

Taxonomic lineage

Bacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Corynebacterineae › Mycobacteriaceae › Mycobacterium

Protein attributes

Sequence length	179 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after rbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes By similarity. HAMAP MF_00014
Subunit structure	Binds ribosomal protein S19 By similarity. HAMAP MF_00014
Subcellular location	Cytoplasm By similarity HAMAP MF_00014.
Domain	The PRC barrel domain binds ribosomal protein S19 By similarity. HAMAP MF_00014
Sequence similarities	Belongs to the rimM family. Contains 1 PRC barrel domain.

Ontologies

Keywords
Biological process	Ribosome biogenesis
Cellular component	Cytoplasm
Molecular function	Chaperone
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	rRNA processing Inferred from electronic annotation. Source: InterPro
Cellular component	ribosome Inferred from electronic annotation. Source: InterPro
Molecular function	ribosome binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 179	179	Ribosome maturation factor rimM HAMAP MF_00014		PRO_1000196564
Regions
	Domain	103 – 176	74	PRC barrel

Sequences

	Sequence		Length	Mass (Da)
	B8ZRW7 [UniParc]. Last modified March 3, 2009. Version 1. Checksum: F95FFD5C3735930E	FASTA	179	19,295
	10 20 30 40 50 60 MHAHGALLEL TIGRVVKAHG IGGEVVVEIR TDDPASRFCP GNILRAKDFP RGGPERRYTV 70 80 90 100 110 120 VYAREHGARL LVRLAGVSDR DAADALRGSL FVIDSLDLPP IDEPDTYYDH QLEGLQVRTM 130 140 150 160 170 MGRDVGVVAE VLHTAAGELL AVRCDSGEVL VPFVGAIVKL VSLDDGIVEI DPPKGLLDL

References

[1]

"Comparative genomic and phylogeographic analysis of Mycobacterium leprae." Monot M., Honore N., Garnier T., Zidane N., Sherafi D., Paniz-Mondolfi A., Matsuoka M., Taylor G.M., Donoghue H.D., Bouwman A., Mays S., Watson C., Lockwood D., Khamispour A., Dowlati Y., Jianping S., Rea T.H., Vera-Cabrera L. , Stefani M.M., Banu S., Macdonald M., Sapkota B.R., Spencer J.S., Thomas J., Harshman K., Singh P., Busso P., Gattiker A., Rougemont J., Brennan P.J., Cole S.T. Nat. Genet. 41:1282-1289(2009) [PubMed: 19881526] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Br4923.

Cross-references

Sequence databases
EMBL GenBank DDBJ	FM211192 Genomic DNA. Translation: CAR71711.1.
RefSeq	YP_002503744.1. NC_011896.1.
3D structure databases
ProteinModelPortal	B8ZRW7.
ModBase	Search...
Protein-protein interaction databases
STRING	B8ZRW7.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	EBMYCT00000087142; EBMYCP00000082024; EBMYCG00000085671.
GeneID	7327279.
GenomeReviews	Gene locus MLBr01616 in contig FM211192_GR.
PATRIC	18045668. VBIMycLep121698_3051.
Organism-specific databases
CMR	Search...
Phylogenomic databases
GeneTree	EBGT00050000017443.
HOGENOM	HBG703775.
OMA	PDEFYDH.
ProtClustDB	PRK00122.
Family and domain databases
HAMAP	MF_00014. Ribosome_mat_RimM. [Tree]
InterPro	IPR011961. 16S_RimM. IPR007903. PRC_barrel. IPR011033. PRC_barrell-like. IPR002676. RimM. IPR009000. Transl_elong_init/rib_B-barrel. [Graphical view]
Gene3D	G3DSA:2.40.30.60. G3DSA:2.40.30.60. 1 hit.
Pfam	PF05239. PRC. 1 hit. PF01782. RimM. 1 hit. [Graphical view]
SUPFAM	SSF50346. PRCH_cytoplasmic. 1 hit. SSF50447. Translat_factor. 1 hit.
TIGRFAMs	TIGR02273. 16S_RimM. 1 hit.
ProtoNet	Search...

Entry information

Entry name

RIMM_MYCLB

Accession

Primary (citable) accession number: B8ZRW7

Entry history

Integrated into UniProtKB/Swiss-Prot:	July 28, 2009
Last sequence update:	March 3, 2009
Last modified:	January 25, 2012
This is version 21 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program