B8ZRW4 (B8ZRW4_MYCLB) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Possible ignal peptidase I EMBL CAR71707.1

Gene names

Ordered Locus Names:

MLBr01612

Organism

Mycobacterium leprae (strain Br4923) [Complete proteome] [HAMAP]

Taxonomic identifier

561304 [NCBI]

Taxonomic lineage

Bacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Corynebacterineae › Mycobacteriaceae › Mycobacterium

Protein attributes

Sequence length	289 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Sequence similarities

Belongs to the peptidase S26 family. RuleBase RU003989

Ontologies

Keywords
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	proteolysis Inferred from electronic annotation. Source: InterPro
Cellular component	integral to membrane Inferred from electronic annotation. Source: InterPro
Molecular function	serine-type peptidase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	B8ZRW4 [UniParc]. Last modified March 3, 2009. Version 1. Checksum: 69F59B03944768DD	FASTA	289	31,086
	10 20 30 40 50 60 MTETTDSVPE PPSDADQLQP KVSICGLDMP AEVSETAAEA AIGVSEPKKR SALWEFAILA 70 80 90 100 110 120 VIAIGLYYVM LTFVARPYLI PSESMEPTLH GCSGCVGDRI MVDKITYRFS SPQPGDVIVF 130 140 150 160 170 180 KGPPSWNTMY KSIRSNNIVL RSVQNALSFV GFVPPDENDL VKRVIAVGGQ TVQCRSDTGL 190 200 210 220 230 240 TVNGKPLKEP YLRPVTMNAD LSFSPCLGSE FGPVTVPQGR LWVMGDNRIH SADSRYHCNS 250 260 270 280 TDVVNGLSCT GDPNSGTVPV SNVIGKARVV VWPPSRWGGV GSVNSQQGQ

References

[1]

"Comparative genomic and phylogeographic analysis of Mycobacterium leprae." Monot M., Honore N., Garnier T., Zidane N., Sherafi D., Paniz-Mondolfi A., Matsuoka M., Taylor G.M., Donoghue H.D., Bouwman A., Mays S., Watson C., Lockwood D., Khamispour A., Dowlati Y., Jianping S., Rea T.H., Vera-Cabrera L. , Stefani M.M., Banu S., Macdonald M., Sapkota B.R., Spencer J.S., Thomas J., Harshman K., Singh P., Busso P., Gattiker A., Rougemont J., Brennan P.J., Cole S.T. Nat. Genet. 41:1282-1289(2009) [PubMed: 19881526] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	FM211192 Genomic DNA. Translation: CAR71707.1.
RefSeq	YP_002503741.1. NC_011896.1.
3D structure databases
ProteinModelPortal	B8ZRW4.
ModBase	Search...
Protein-protein interaction databases
STRING	B8ZRW4.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	EBMYCT00000086394; EBMYCP00000082728; EBMYCG00000086266.
GeneID	7326633.
GenomeReviews	Gene locus MLBr01612 in contig FM211192_GR.
PATRIC	18045658. VBIMycLep121698_3046.
Organism-specific databases
CMR	Search...
Phylogenomic databases
GeneTree	EBGT00050000017115.
HOGENOM	HBG596607.
OMA	TVECCDD.
ProtClustDB	CLSK792152.
Family and domain databases
InterPro	IPR000223. Pept_S26A_signal_pept_1. IPR019758. Pept_S26A_signal_pept_1_CS. IPR019756. Pept_S26A_signal_pept_1_Ser-AS. IPR019759. Peptidase_S24_S26. IPR015927. Peptidase_S24_S26A/B/C. IPR011056. Peptidase_S24_S26A/B/C_b-rbn. IPR019533. Peptidase_S26. [Graphical view]
Gene3D	G3DSA:2.10.109.10. Pept_S24_S26_C. 2 hits.
Pfam	PF00717. Peptidase_S24. 1 hit. PF10502. Peptidase_S26. 1 hit. [Graphical view]
PRINTS	PR00727. LEADERPTASE.
SUPFAM	SSF51306. Pept_S24_S26_C. 1 hit.
TIGRFAMs	TIGR02227. Sigpep_I_bact. 1 hit.
PROSITE	PS00501. SPASE_I_1. 1 hit. PS00761. SPASE_I_3. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

B8ZRW4_MYCLB

Accession

Primary (citable) accession number: B8ZRW4

Entry history

Integrated into UniProtKB/TrEMBL:	March 3, 2009
Last sequence update:	March 3, 2009
Last modified:	December 14, 2011
This is version 23 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)