B8ZRN5 (RL21_MYCLB) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
50S ribosomal protein L21

Gene names

Name:	rplU
Ordered Locus Names:	MLBr01467

Organism

Mycobacterium leprae (strain Br4923) [Complete proteome] [HAMAP]

Taxonomic identifier

561304 [NCBI]

Taxonomic lineage

Bacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Corynebacterineae › Mycobacteriaceae › Mycobacterium

Protein attributes

Sequence length	103 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	This protein binds to 23S rRNA in the presence of protein L20 By similarity. HAMAP MF_01363
Subunit structure	Part of the 50S ribosomal subunit. Contacts protein L20 By similarity.
Sequence similarities	Belongs to the ribosomal protein L21P family.

Ontologies

Keywords
Ligand	RNA-binding rRNA-binding
Molecular function	Ribonucleoprotein Ribosomal protein
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	translation Inferred from electronic annotation. Source: InterPro
Cellular component	ribosome Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	rRNA binding Inferred from electronic annotation. Source: UniProtKB-KW structural constituent of ribosome Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 103	103	50S ribosomal protein L21 HAMAP MF_01363		PRO_1000166732

Sequences

	Sequence		Length	Mass (Da)
	B8ZRN5 [UniParc]. Last modified March 3, 2009. Version 1. Checksum: 05EE6D688438036A	FASTA	103	11,148
	10 20 30 40 50 60 MATYAIVKTG GKQYKVAVGD VVKIEKLDFE PGAKVSLPVT LVVDGATVTT NAKALAKVAV 70 80 90 100 TGKVLEHTKG PKIRIHKFKN KTGYHKRQGH RQQLTVLKVT GIK

References

[1]

"Comparative genomic and phylogeographic analysis of Mycobacterium leprae." Monot M., Honore N., Garnier T., Zidane N., Sherafi D., Paniz-Mondolfi A., Matsuoka M., Taylor G.M., Donoghue H.D., Bouwman A., Mays S., Watson C., Lockwood D., Khamispour A., Dowlati Y., Jianping S., Rea T.H., Vera-Cabrera L. , Stefani M.M., Banu S., Macdonald M., Sapkota B.R., Spencer J.S., Thomas J., Harshman K., Singh P., Busso P., Gattiker A., Rougemont J., Brennan P.J., Cole S.T. Nat. Genet. 41:1282-1289(2009) [PubMed: 19881526] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Br4923.

Cross-references

Sequence databases
EMBL GenBank DDBJ	FM211192 Genomic DNA. Translation: CAR71561.1.
RefSeq	YP_002503662.1. NC_011896.1.
3D structure databases
ProteinModelPortal	B8ZRN5.
ModBase	Search...
Protein-protein interaction databases
STRING	B8ZRN5.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	EBMYCT00000086781; EBMYCP00000081853; EBMYCG00000086464.
GeneID	7326664.
GenomeReviews	Gene locus MLBr01467 in contig FM211192_GR.
PATRIC	18045062. VBIMycLep121698_2749.
Organism-specific databases
CMR	Search...
Phylogenomic databases
GeneTree	EBGT00050000017407.
HOGENOM	HBG706775.
OMA	IKVEQIA.
ProtClustDB	PRK05573.
Family and domain databases
HAMAP	MF_01363. Ribosomal_L21. [Tree]
InterPro	IPR001787. Ribosomal_L21. IPR018258. Ribosomal_L21_CS. [Graphical view]
PANTHER	PTHR21349. Ribosomal_L21p. 1 hit.
Pfam	PF00829. Ribosomal_L21p. 1 hit. [Graphical view]
TIGRFAMs	TIGR00061. L21. 1 hit.
PROSITE	PS01169. RIBOSOMAL_L21. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

RL21_MYCLB

Accession

Primary (citable) accession number: B8ZRN5

Entry history

Integrated into UniProtKB/Swiss-Prot:	July 28, 2009
Last sequence update:	March 3, 2009
Last modified:	January 25, 2012
This is version 19 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program