B8ZRI3 (B8ZRI3_MYCLB) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
GTPase Der RuleBase RU004481

Gene names

Ordered Locus Names:

MLBr01372

Organism

Mycobacterium leprae (strain Br4923) [Complete proteome] [HAMAP]

Taxonomic identifier

561304 [NCBI]

Taxonomic lineage

Bacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Corynebacterineae › Mycobacteriaceae › Mycobacterium

Protein attributes

Sequence length	462 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	GTPase that plays an essential role in the late steps of ribosome biogenesis By similarity. RuleBase RU004481
Sequence similarities	Belongs to the Era/MnmE GTP-binding protein family. Der subfamily. RuleBase RU004481

Ontologies

Keywords
Domain	Repeat RuleBase RU004481
Ligand	GTP-binding RuleBase RU004481 Nucleotide-binding
Technical term	Complete proteome
Gene Ontology (GO)
Cellular component	intracellular Inferred from electronic annotation. Source: InterPro
Molecular function	GTP binding Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	B8ZRI3 [UniParc]. Last modified March 3, 2009. Version 1. Checksum: 07C3E10BE492CD01	FASTA	462	50,239
	10 20 30 40 50 60 MVSQDGTWSD ESDWELDDSD LAEFGPVVAV VGRPNVGKST LVNRILGRRE AVVQDVPGVT 70 80 90 100 110 120 RDRVSYDAMW TGRRFVVQDT GGWEPDAKGL KRLVAEQASV AMRTADAVIL VVDVGVGATD 130 140 150 160 170 180 ADEAAARILL RSGKLVFLAA NKVDGEKGES DASALWSLGL GEPHAISAMH GRGVADLLDK 190 200 210 220 230 240 VLAALPNVAE STSLDGGLRR VALVGKPNVG KSSLLNKLAG DQRSVVHEAA GTTVDPVDSL 250 260 270 280 290 300 IEMGGRVWRF VDTAGLRRKV GQASGHEFYA SVRTHGAIDS AEVVIMLIDA SEPLTGQDQR 310 320 330 340 350 360 VLSMVIDAGR ALVLAFNKWD LVDEDRCDLL EREIDRELVQ VRWAQRVNIS AKTGRAVQKL 370 380 390 400 410 420 VPAMENSLAS WDTRIATGPL NIWIKAVVAA TPPPVRGGKQ PRILFATQAT ARPPTFVLFT 430 440 450 460 TGFLEACYRR FLERRLRETF GFEGSPIRIN VRVREKRGLK RR

References

[1]

"Comparative genomic and phylogeographic analysis of Mycobacterium leprae." Monot M., Honore N., Garnier T., Zidane N., Sherafi D., Paniz-Mondolfi A., Matsuoka M., Taylor G.M., Donoghue H.D., Bouwman A., Mays S., Watson C., Lockwood D., Khamispour A., Dowlati Y., Jianping S., Rea T.H., Vera-Cabrera L. , Stefani M.M., Banu S., Macdonald M., Sapkota B.R., Spencer J.S., Thomas J., Harshman K., Singh P., Busso P., Gattiker A., Rougemont J., Brennan P.J., Cole S.T. Nat. Genet. 41:1282-1289(2009) [PubMed: 19881526] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	FM211192 Genomic DNA. Translation: CAR71467.1.
RefSeq	YP_002503610.1. NC_011896.1.
3D structure databases
ProteinModelPortal	B8ZRI3.
ModBase	Search...
Protein-protein interaction databases
STRING	B8ZRI3.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	EBMYCT00000086497; EBMYCP00000082921; EBMYCG00000085364.
GeneID	7326113.
GenomeReviews	Gene locus MLBr01372 in contig FM211192_GR.
PATRIC	18044630. VBIMycLep121698_2533.
Organism-specific databases
CMR	Search...
Phylogenomic databases
GeneTree	EBGT00050000016947.
HOGENOM	HBG592135.
OMA	QGADFYA.
ProtClustDB	PRK03003.
Family and domain databases
HAMAP	MF_00195. GTPase_Der. [Tree]
InterPro	IPR016484. GTP-bd_EngA. IPR006073. GTP_binding_domain. IPR015946. KH_dom-like_a/b. IPR005225. Small_GTP-bd_dom. [Graphical view]
Gene3D	G3DSA:3.30.300.20. KH_prok. 1 hit.
PANTHER	PTHR11649:SF5. PTHR11649:SF5. 1 hit.
Pfam	PF01926. MMR_HSR1. 2 hits. [Graphical view]
PIRSF	PIRSF006485. GTP-binding_EngA. 1 hit.
PRINTS	PR00326. GTP1OBG.
TIGRFAMs	TIGR03594. GTPase_EngA. 1 hit. TIGR00231. Small_GTP. 2 hits.
ProtoNet	Search...

Entry information

Entry name

B8ZRI3_MYCLB

Accession

Primary (citable) accession number: B8ZRI3

Entry history

Integrated into UniProtKB/TrEMBL:	March 3, 2009
Last sequence update:	March 3, 2009
Last modified:	January 25, 2012
This is version 28 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)