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B8ZRF9

- B8ZRF9_MYCLB

UniProt

B8ZRF9 - B8ZRF9_MYCLB

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Protein

Sec-independent protein translocase protein TatC

Gene

tatC

Organism
Mycobacterium leprae (strain Br4923)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides.UniRule annotation

GO - Molecular functioni

  1. protein transmembrane transporter activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. protein transport by the Tat complex Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Biological processi

Protein transport, TranslocationUniRule annotation, Transport

Enzyme and pathway databases

BioCyciMLEP561304:GJP6-1357-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Sec-independent protein translocase protein TatCUniRule annotation
Gene namesi
Name:tatCUniRule annotation
Ordered Locus Names:MLBr01332Imported
OrganismiMycobacterium leprae (strain Br4923)Imported
Taxonomic identifieri561304 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaActinobacteridaeActinomycetalesCorynebacterineaeMycobacteriaceaeMycobacterium
ProteomesiUP000006900: Chromosome

Subcellular locationi

Cell membrane UniRule annotation; Multi-pass membrane protein UniRule annotation

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei14 – 3421HelicalUniRule annotationAdd
BLAST
Transmembranei85 – 10521HelicalUniRule annotationAdd
BLAST
Transmembranei118 – 13821HelicalUniRule annotationAdd
BLAST
Transmembranei166 – 18621HelicalUniRule annotationAdd
BLAST
Transmembranei205 – 22521HelicalUniRule annotationAdd
BLAST
Transmembranei226 – 24621HelicalUniRule annotationAdd
BLAST

GO - Cellular componenti

  1. integral component of plasma membrane Source: UniProtKB-HAMAP
  2. TAT protein transport complex Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Cellular componenti

Cell membraneUniRule annotation, Membrane

Interactioni

Subunit structurei

The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.UniRule annotation

Protein-protein interaction databases

STRINGi561304.MLBr_01332.

Structurei

3D structure databases

ProteinModelPortaliB8ZRF9.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the TatC family.UniRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helixUniRule annotation

Phylogenomic databases

eggNOGiCOG0805.
KOiK03118.
OMAiEHLYELR.
OrthoDBiEOG60SCQS.

Family and domain databases

HAMAPiMF_00902. TatC.
InterProiIPR019820. Sec-indep_translocase_CS.
IPR002033. TatC.
[Graphical view]
PfamiPF00902. TatC. 1 hit.
[Graphical view]
PRINTSiPR01840. TATCFAMILY.
TIGRFAMsiTIGR00945. tatC. 1 hit.
PROSITEiPS01218. TATC. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

B8ZRF9-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MSLIDHLTEL RTRLLISLAA IVVTTIFGFI WYSHSIFGLE SLGEWLRRPY
60 70 80 90 100
CSLPQSARAD ISPDGQCRLL ATAPFDQFML RIKVGMAAGI VLASPVWFYQ
110 120 130 140 150
LWAFITPGLY TKERRFTVAF VVPAAVLFAG GTVLAYLVLS KALGFLLIVG
160 170 180 190 200
SGVQVTALSG DRYFGFLLNL LVVFGVSFEF PLLIVMLNIA GLLTYQRLKS
210 220 230 240 250
WRRGLIFAMF VFAAVFTPGS DPFSMTALGA ALTVLLELAI QLVRLHDKRR
260 270 280
VKHEALIADD EASVIEPPSS IPERSYTATR SHDDVT
Length:286
Mass (Da):31,623
Last modified:March 3, 2009 - v1
Checksum:i57E6DDC22F9B8145
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
FM211192 Genomic DNA. Translation: CAR71427.1.
RefSeqiWP_010908277.1. NC_011896.1.
YP_002503586.1. NC_011896.1.

Genome annotation databases

EnsemblBacteriaiCAR71427; CAR71427; MLBr01332.
GeneIDi7326477.
KEGGimlb:MLBr_01332.
PATRICi18044472. VBIMycLep121698_2458.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
FM211192 Genomic DNA. Translation: CAR71427.1 .
RefSeqi WP_010908277.1. NC_011896.1.
YP_002503586.1. NC_011896.1.

3D structure databases

ProteinModelPortali B8ZRF9.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 561304.MLBr_01332.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai CAR71427 ; CAR71427 ; MLBr01332 .
GeneIDi 7326477.
KEGGi mlb:MLBr_01332.
PATRICi 18044472. VBIMycLep121698_2458.

Phylogenomic databases

eggNOGi COG0805.
KOi K03118.
OMAi EHLYELR.
OrthoDBi EOG60SCQS.

Enzyme and pathway databases

BioCyci MLEP561304:GJP6-1357-MONOMER.

Family and domain databases

HAMAPi MF_00902. TatC.
InterProi IPR019820. Sec-indep_translocase_CS.
IPR002033. TatC.
[Graphical view ]
Pfami PF00902. TatC. 1 hit.
[Graphical view ]
PRINTSi PR01840. TATCFAMILY.
TIGRFAMsi TIGR00945. tatC. 1 hit.
PROSITEi PS01218. TATC. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Br4923Imported.

Entry informationi

Entry nameiB8ZRF9_MYCLB
AccessioniPrimary (citable) accession number: B8ZRF9
Entry historyi
Integrated into UniProtKB/TrEMBL: March 3, 2009
Last sequence update: March 3, 2009
Last modified: October 29, 2014
This is version 37 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

External Data

Dasty 3