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B8ZRF9 (B8ZRF9_MYCLB) Unreviewed, UniProtKB/TrEMBL

Last modified February 19, 2014. Version 33. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Sec-independent protein translocase protein TatC HAMAP-Rule MF_00902
Gene names
Name:tatC HAMAP-Rule MF_00902
Ordered Locus Names:MLBr01332 EMBL CAR71427.1
OrganismMycobacterium leprae (strain Br4923) [Complete proteome] [HAMAP] EMBL CAR71427.1
Taxonomic identifier561304 [NCBI]
Taxonomic lineageBacteriaActinobacteriaActinobacteridaeActinomycetalesCorynebacterineaeMycobacteriaceaeMycobacterium

Protein attributes

Sequence length286 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides By similarity. HAMAP-Rule MF_00902

Subunit structure

The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon By similarity. HAMAP-Rule MF_00902

Subcellular location

Cell membrane; Multi-pass membrane protein By similarity HAMAP-Rule MF_00902.

Sequence similarities

Belongs to the TatC family. HAMAP-Rule MF_00902

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Regions

Transmembrane14 – 3421Helical; By similarity HAMAP-Rule MF_00902
Transmembrane85 – 10521Helical; By similarity HAMAP-Rule MF_00902
Transmembrane118 – 13821Helical; By similarity HAMAP-Rule MF_00902
Transmembrane166 – 18621Helical; By similarity HAMAP-Rule MF_00902
Transmembrane205 – 22521Helical; By similarity HAMAP-Rule MF_00902
Transmembrane226 – 24621Helical; By similarity HAMAP-Rule MF_00902

Sequences

Sequence LengthMass (Da)Tools
B8ZRF9 [UniParc].

Last modified March 3, 2009. Version 1.
Checksum: 57E6DDC22F9B8145

FASTA28631,623
        10         20         30         40         50         60 
MSLIDHLTEL RTRLLISLAA IVVTTIFGFI WYSHSIFGLE SLGEWLRRPY CSLPQSARAD 

        70         80         90        100        110        120 
ISPDGQCRLL ATAPFDQFML RIKVGMAAGI VLASPVWFYQ LWAFITPGLY TKERRFTVAF 

       130        140        150        160        170        180 
VVPAAVLFAG GTVLAYLVLS KALGFLLIVG SGVQVTALSG DRYFGFLLNL LVVFGVSFEF 

       190        200        210        220        230        240 
PLLIVMLNIA GLLTYQRLKS WRRGLIFAMF VFAAVFTPGS DPFSMTALGA ALTVLLELAI 

       250        260        270        280 
QLVRLHDKRR VKHEALIADD EASVIEPPSS IPERSYTATR SHDDVT 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
FM211192 Genomic DNA. Translation: CAR71427.1.
RefSeqYP_002503586.1. NC_011896.1.

3D structure databases

ProteinModelPortalB8ZRF9.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING561304.MLBr_01332.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaCAR71427; CAR71427; MLBr01332.
GeneID7326477.
KEGGmlb:MLBr_01332.
PATRIC18044472. VBIMycLep121698_2458.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0805.
KOK03118.
OMAYLDFVLL.
OrthoDBEOG60SCQS.
ProtClustDBCLSK2751554.

Enzyme and pathway databases

BioCycMLEP561304:GJP6-1357-MONOMER.

Family and domain databases

HAMAPMF_00902. TatC.
InterProIPR019820. Sec-indep_translocase_CS.
IPR002033. TatC.
[Graphical view]
PfamPF00902. TatC. 1 hit.
[Graphical view]
PRINTSPR01840. TATCFAMILY.
TIGRFAMsTIGR00945. tatC. 1 hit.
PROSITEPS01218. TATC. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameB8ZRF9_MYCLB
AccessionPrimary (citable) accession number: B8ZRF9
Entry history
Integrated into UniProtKB/TrEMBL: March 3, 2009
Last sequence update: March 3, 2009
Last modified: February 19, 2014
This is version 33 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)