B8ZR57 (MURI_MYCLB) Reviewed, UniProtKB/Swiss-Prot
Last modified
January 25, 2012.
Version 21.
History...
Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order
Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize orderNames and origin
| Protein names | Recommended name: Glutamate racemase EC=5.1.1.3 | ||||
| Gene names |
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| Organism | Mycobacterium leprae (strain Br4923) [Complete proteome] [HAMAP] | ||||
| Taxonomic identifier | 561304 [NCBI] | ||||
| Taxonomic lineage | Bacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Corynebacterineae › Mycobacteriaceae › Mycobacterium |
Protein attributes
| Sequence length | 272 AA. |
| Sequence status | Complete. |
| Protein existence | Inferred from homology |
General annotation (Comments)
| Function | Provides the (R)-glutamate required for cell wall biosynthesis By similarity. HAMAP MF_00258 |
| Catalytic activity | L-glutamate = D-glutamate. HAMAP MF_00258 |
| Pathway | Cell wall biogenesis; peptidoglycan biosynthesis. HAMAP MF_00258 |
| Sequence similarities | Belongs to the aspartate/glutamate racemases family. |
Ontologies
| Keywords | |
|---|---|
| Biological process | Cell shape Cell wall biogenesis/degradation Peptidoglycan synthesis |
| Molecular function | Isomerase |
| Technical term | Complete proteome |
| Gene Ontology (GO) | |
| Biological process | cellular cell wall organization Inferred from electronic annotation. Source: UniProtKB-KW peptidoglycan biosynthetic processInferred from electronic annotation. Source: UniProtKB-KW regulation of cell shapeInferred from electronic annotation. Source: UniProtKB-KW |
| Molecular function | glutamate racemase activity Inferred from electronic annotation. Source: EC |
| Complete GO annotation... | |
Sequence annotation (Features)
| Feature key | Position(s) | Length | Description | Graphical view | Feature identifier | ||
Molecule processing | |||||||
|---|---|---|---|---|---|---|---|
| Chain | 1 – 272 | 272 | Glutamate racemase HAMAP MF_00258 | PRO_1000125614 | |||
Sequences
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References
| [1] | "Comparative genomic and phylogeographic analysis of Mycobacterium leprae." Monot M., Honore N., Garnier T., Zidane N., Sherafi D., Paniz-Mondolfi A., Matsuoka M., Taylor G.M., Donoghue H.D., Bouwman A., Mays S., Watson C., Lockwood D., Khamispour A., Dowlati Y., Jianping S., Rea T.H., Vera-Cabrera L. Cole S.T.Nat. Genet. 41:1282-1289(2009) [PubMed: 19881526] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Br4923. |
Cross-references
Sequence databases | |
|---|---|
| EMBL GenBank DDBJ | FM211192 Genomic DNA. Translation: CAR71267.1. |
| RefSeq | YP_002503484.1. NC_011896.1. |
3D structure databases | |
| ProteinModelPortal | B8ZR57. |
| ModBase | Search... |
Protein-protein interaction databases | |
| STRING | B8ZR57. |
Protocols and materials databases | |
| StructuralBiologyKnowledgebase | Search... |
Genome annotation databases | |
| EnsemblBacteria | EBMYCT00000085158; EBMYCP00000081915; EBMYCG00000085069. |
| GeneID | 7327047. |
| GenomeReviews | Gene locus MLBr01172 in contig FM211192_GR. |
| PATRIC | 18043818. VBIMycLep121698_2135. |
Organism-specific databases | |
| CMR | Search... |
Phylogenomic databases | |
| GeneTree | EBGT00050000016063. |
| HOGENOM | HBG645102. |
| OMA | PQEDTIY. |
| ProtClustDB | PRK00865. |
Family and domain databases | |
| HAMAP | MF_00258. Glu_racemase. [Tree] |
| InterPro | IPR015942. Asp/Glu/hydantoin_racemase. IPR001920. Asp/Glu_race. IPR018187. Asp/Glu_racemase_AS. IPR004391. Glu_race. [Graphical view] |
| Gene3D | G3DSA:3.40.50.1860. Asp/Glu_race. 1 hit. |
| PANTHER | PTHR21198. PTHR21198. 1 hit. |
| Pfam | PF01177. Asp_Glu_race. 1 hit. [Graphical view] |
| SUPFAM | SSF53681. Asp/Glu_race. 2 hits. |
| TIGRFAMs | TIGR00067. Glut_race. 1 hit. |
| PROSITE | PS00923. ASP_GLU_RACEMASE_1. 1 hit. PS00924. ASP_GLU_RACEMASE_2. 1 hit. [Graphical view] |
| ProtoNet | Search... |
Entry information
| Entry name | MURI_MYCLB | ||||||||
| Accession | Primary (citable) accession number: B8ZR57 | ||||||||
| Entry history |
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| Entry status | Reviewed (UniProtKB/Swiss-Prot) | ||||||||
| Annotation program | Prokaryotic Protein Annotation Program | ||||||||
Relevant documents
| PATHWAY comments Index of metabolic and biosynthesis pathways |
| SIMILARITY comments Index of protein domains and families |

Clusters with