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B8ZN60

- TRPF_STRPJ

UniProt

B8ZN60 - TRPF_STRPJ

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Protein

N-(5'-phosphoribosyl)anthranilate isomerase

Gene

trpF

Organism
Streptococcus pneumoniae (strain ATCC 700669 / Spain 23F-1)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Catalytic activityi

N-(5-phospho-beta-D-ribosyl)anthranilate = 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate.UniRule annotation

Pathwayi

GO - Molecular functioni

  1. phosphoribosylanthranilate isomerase activity Source: UniProtKB-EC

GO - Biological processi

  1. tryptophan biosynthetic process Source: UniProtKB-UniPathway
Complete GO annotation...

Keywords - Molecular functioni

Isomerase

Keywords - Biological processi

Amino-acid biosynthesis, Aromatic amino acid biosynthesis, Tryptophan biosynthesis

Enzyme and pathway databases

BioCyciSPNE561276:GJFJ-1757-MONOMER.
UniPathwayiUPA00035; UER00042.

Names & Taxonomyi

Protein namesi
Recommended name:
N-(5'-phosphoribosyl)anthranilate isomeraseUniRule annotation (EC:5.3.1.24UniRule annotation)
Short name:
PRAIUniRule annotation
Gene namesi
Name:trpFUniRule annotation
Ordered Locus Names:SPN23F18330
OrganismiStreptococcus pneumoniae (strain ATCC 700669 / Spain 23F-1)
Taxonomic identifieri561276 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliLactobacillalesStreptococcaceaeStreptococcus
ProteomesiUP000002600: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 199199N-(5'-phosphoribosyl)anthranilate isomerasePRO_1000197125Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi561276.SPN23F_18330.

Structurei

3D structure databases

ProteinModelPortaliB8ZN60.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the TrpF family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0135.
KOiK01817.
OMAiPDYAGFV.
OrthoDBiEOG6N94DF.

Family and domain databases

Gene3Di3.20.20.70. 1 hit.
HAMAPiMF_00135. PRAI.
InterProiIPR013785. Aldolase_TIM.
IPR001240. PRAI_dom.
IPR011060. RibuloseP-bd_barrel.
[Graphical view]
PfamiPF00697. PRAI. 1 hit.
[Graphical view]
SUPFAMiSSF51366. SSF51366. 1 hit.

Sequencei

Sequence statusi: Complete.

B8ZN60-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MTKVKICGLS TKEAVETAVS AGADYIGFVF APSKRQVTLE EAAELAKLIP
60 70 80 90 100
ADVKKVGVFV SPSRVELLEA IDKVGLDLVQ VHGQVAADLF ENLPCASIQA
110 120 130 140 150
VQVDGNGHVP NSQADYLLFD APVAGSGQSF DWGQLDTTGL AQPFFIAGGL
160 170 180 190
NEDNVVKAIQ HFTPYAVDVS SGVETDGQKN HEKIRRFIER VKHGISGTK
Length:199
Mass (Da):21,235
Last modified:March 3, 2009 - v1
Checksum:iA0EB9CE045F5ED9D
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
FM211187 Genomic DNA. Translation: CAR69597.1.
RefSeqiYP_002511711.1. NC_011900.1.

Genome annotation databases

EnsemblBacteriaiCAR69597; CAR69597; SPN23F18330.
GeneIDi7327646.
KEGGisne:SPN23F_18330.
PATRICi19675051. VBIStrPne132160_1927.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
FM211187 Genomic DNA. Translation: CAR69597.1 .
RefSeqi YP_002511711.1. NC_011900.1.

3D structure databases

ProteinModelPortali B8ZN60.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 561276.SPN23F_18330.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai CAR69597 ; CAR69597 ; SPN23F18330 .
GeneIDi 7327646.
KEGGi sne:SPN23F_18330.
PATRICi 19675051. VBIStrPne132160_1927.

Phylogenomic databases

eggNOGi COG0135.
KOi K01817.
OMAi PDYAGFV.
OrthoDBi EOG6N94DF.

Enzyme and pathway databases

UniPathwayi UPA00035 ; UER00042 .
BioCyci SPNE561276:GJFJ-1757-MONOMER.

Family and domain databases

Gene3Di 3.20.20.70. 1 hit.
HAMAPi MF_00135. PRAI.
InterProi IPR013785. Aldolase_TIM.
IPR001240. PRAI_dom.
IPR011060. RibuloseP-bd_barrel.
[Graphical view ]
Pfami PF00697. PRAI. 1 hit.
[Graphical view ]
SUPFAMi SSF51366. SSF51366. 1 hit.
ProtoNeti Search...

Publicationsi

  1. "Role of conjugative elements in the evolution of the multidrug-resistant pandemic clone Streptococcus pneumoniae Spain23F ST81."
    Croucher N.J., Walker D., Romero P., Lennard N., Paterson G.K., Bason N.C., Mitchell A.M., Quail M.A., Andrew P.W., Parkhill J., Bentley S.D., Mitchell T.J.
    J. Bacteriol. 191:1480-1489(2009) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 700669 / Spain 23F-1.

Entry informationi

Entry nameiTRPF_STRPJ
AccessioniPrimary (citable) accession number: B8ZN60
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 28, 2009
Last sequence update: March 3, 2009
Last modified: October 1, 2014
This is version 38 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3