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B8ZN60

- TRPF_STRPJ

UniProt

B8ZN60 - TRPF_STRPJ

Protein

N-(5'-phosphoribosyl)anthranilate isomerase

Gene

trpF

Organism
Streptococcus pneumoniae (strain ATCC 700669 / Spain 23F-1)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 38 (01 Oct 2014)
      Sequence version 1 (03 Mar 2009)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    N-(5-phospho-beta-D-ribosyl)anthranilate = 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate.UniRule annotation

    Pathwayi

    GO - Molecular functioni

    1. phosphoribosylanthranilate isomerase activity Source: UniProtKB-EC

    GO - Biological processi

    1. tryptophan biosynthetic process Source: UniProtKB-UniPathway

    Keywords - Molecular functioni

    Isomerase

    Keywords - Biological processi

    Amino-acid biosynthesis, Aromatic amino acid biosynthesis, Tryptophan biosynthesis

    Enzyme and pathway databases

    BioCyciSPNE561276:GJFJ-1757-MONOMER.
    UniPathwayiUPA00035; UER00042.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    N-(5'-phosphoribosyl)anthranilate isomeraseUniRule annotation (EC:5.3.1.24UniRule annotation)
    Short name:
    PRAIUniRule annotation
    Gene namesi
    Name:trpFUniRule annotation
    Ordered Locus Names:SPN23F18330
    OrganismiStreptococcus pneumoniae (strain ATCC 700669 / Spain 23F-1)
    Taxonomic identifieri561276 [NCBI]
    Taxonomic lineageiBacteriaFirmicutesBacilliLactobacillalesStreptococcaceaeStreptococcus
    ProteomesiUP000002600: Chromosome

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 199199N-(5'-phosphoribosyl)anthranilate isomerasePRO_1000197125Add
    BLAST

    Interactioni

    Protein-protein interaction databases

    STRINGi561276.SPN23F_18330.

    Structurei

    3D structure databases

    ProteinModelPortaliB8ZN60.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the TrpF family.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG0135.
    KOiK01817.
    OMAiPDYAGFV.
    OrthoDBiEOG6N94DF.

    Family and domain databases

    Gene3Di3.20.20.70. 1 hit.
    HAMAPiMF_00135. PRAI.
    InterProiIPR013785. Aldolase_TIM.
    IPR001240. PRAI_dom.
    IPR011060. RibuloseP-bd_barrel.
    [Graphical view]
    PfamiPF00697. PRAI. 1 hit.
    [Graphical view]
    SUPFAMiSSF51366. SSF51366. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    B8ZN60-1 [UniParc]FASTAAdd to Basket

    « Hide

    MTKVKICGLS TKEAVETAVS AGADYIGFVF APSKRQVTLE EAAELAKLIP    50
    ADVKKVGVFV SPSRVELLEA IDKVGLDLVQ VHGQVAADLF ENLPCASIQA 100
    VQVDGNGHVP NSQADYLLFD APVAGSGQSF DWGQLDTTGL AQPFFIAGGL 150
    NEDNVVKAIQ HFTPYAVDVS SGVETDGQKN HEKIRRFIER VKHGISGTK 199
    Length:199
    Mass (Da):21,235
    Last modified:March 3, 2009 - v1
    Checksum:iA0EB9CE045F5ED9D
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    FM211187 Genomic DNA. Translation: CAR69597.1.
    RefSeqiYP_002511711.1. NC_011900.1.

    Genome annotation databases

    EnsemblBacteriaiCAR69597; CAR69597; SPN23F18330.
    GeneIDi7327646.
    KEGGisne:SPN23F_18330.
    PATRICi19675051. VBIStrPne132160_1927.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    FM211187 Genomic DNA. Translation: CAR69597.1 .
    RefSeqi YP_002511711.1. NC_011900.1.

    3D structure databases

    ProteinModelPortali B8ZN60.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 561276.SPN23F_18330.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai CAR69597 ; CAR69597 ; SPN23F18330 .
    GeneIDi 7327646.
    KEGGi sne:SPN23F_18330.
    PATRICi 19675051. VBIStrPne132160_1927.

    Phylogenomic databases

    eggNOGi COG0135.
    KOi K01817.
    OMAi PDYAGFV.
    OrthoDBi EOG6N94DF.

    Enzyme and pathway databases

    UniPathwayi UPA00035 ; UER00042 .
    BioCyci SPNE561276:GJFJ-1757-MONOMER.

    Family and domain databases

    Gene3Di 3.20.20.70. 1 hit.
    HAMAPi MF_00135. PRAI.
    InterProi IPR013785. Aldolase_TIM.
    IPR001240. PRAI_dom.
    IPR011060. RibuloseP-bd_barrel.
    [Graphical view ]
    Pfami PF00697. PRAI. 1 hit.
    [Graphical view ]
    SUPFAMi SSF51366. SSF51366. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. "Role of conjugative elements in the evolution of the multidrug-resistant pandemic clone Streptococcus pneumoniae Spain23F ST81."
      Croucher N.J., Walker D., Romero P., Lennard N., Paterson G.K., Bason N.C., Mitchell A.M., Quail M.A., Andrew P.W., Parkhill J., Bentley S.D., Mitchell T.J.
      J. Bacteriol. 191:1480-1489(2009) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 700669 / Spain 23F-1.

    Entry informationi

    Entry nameiTRPF_STRPJ
    AccessioniPrimary (citable) accession number: B8ZN60
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: July 28, 2009
    Last sequence update: March 3, 2009
    Last modified: October 1, 2014
    This is version 38 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome

    Documents

    1. PATHWAY comments
      Index of metabolic and biosynthesis pathways
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3