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B8ZLS6

- WHIA_STRPJ

UniProt

B8ZLS6 - WHIA_STRPJ

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Protein

Putative sporulation transcription regulator WhiA

Gene

whiA

Organism
Streptococcus pneumoniae (strain ATCC 700669 / Spain 23F-1)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

May be required for sporulation.UniRule annotation

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
DNA bindingi272 – 30332H-T-H motifUniRule annotationAdd
BLAST

GO - Molecular functioni

  1. DNA binding Source: UniProtKB-KW
  2. endonuclease activity Source: InterPro

GO - Biological processi

  1. regulation of sporulation Source: UniProtKB-HAMAP
  2. regulation of transcription, DNA-templated Source: UniProtKB-KW
  3. transcription, DNA-templated Source: UniProtKB-KW
Complete GO annotation...

Keywords - Biological processi

Transcription, Transcription regulation

Keywords - Ligandi

DNA-binding

Enzyme and pathway databases

BioCyciSPNE561276:GJFJ-1516-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Putative sporulation transcription regulator WhiAUniRule annotation
Gene namesi
Name:whiAUniRule annotation
Ordered Locus Names:SPN23F15810
OrganismiStreptococcus pneumoniae (strain ATCC 700669 / Spain 23F-1)
Taxonomic identifieri561276 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliLactobacillalesStreptococcaceaeStreptococcus
ProteomesiUP000002600: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 303303Putative sporulation transcription regulator WhiAPRO_0000376577Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi561276.SPN23F_15810.

Family & Domainsi

Sequence similaritiesi

Belongs to the WhiA transcriptional regulatory family.UniRule annotation

Phylogenomic databases

eggNOGiCOG1481.
KOiK09762.
OMAiHKFMLDA.
OrthoDBiEOG68WR87.

Family and domain databases

Gene3Di3.10.28.10. 1 hit.
HAMAPiMF_01420. HTH_type_WhiA.
InterProiIPR027434. Homing_endonucl.
IPR018478. Sporu_reg_WhiA_N_dom.
IPR003802. Sporulation_regulator_WhiA.
IPR023054. Sporulation_regulator_WhiA_C.
[Graphical view]
PfamiPF02650. HTH_WhiA. 1 hit.
PF10298. WhiA_N. 1 hit.
[Graphical view]
SUPFAMiSSF55608. SSF55608. 1 hit.
TIGRFAMsiTIGR00647. MG103. 1 hit.

Sequencei

Sequence statusi: Complete.

B8ZLS6-1 [UniParc]FASTAAdd to Basket

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        10         20         30         40         50
MSFTVAVKEE ILGQHHLSRH ELSAIIKMSG SIGLSTSGLT LSVVTENAKL
60 70 80 90 100
ARHLYESFLH FYEIKSEIRH HQRSNLRKNR VYTVFTDEKV QDLLSDLHLA
110 120 130 140 150
DSFFGLETGI DEAILSDEEA GRAYLCGAFL ANGSIRDPES GKYQLEISSV
160 170 180 190 200
YLDHAQGIAS LLQQFLLDAK VLERKKGAVT YLQRAEDIMD FLIVIGAMQA
210 220 230 240 250
RDDFERVKIL RETRNDLNRA NNAETANIAR TVSASMKTIN NISKIKDIMG
260 270 280 290 300
LENLPVDLQE VAQLRIQHPD YSIQQLADSL STPLTKSGVN HRLRKINKIA

DEL
Length:303
Mass (Da):34,062
Last modified:March 3, 2009 - v1
Checksum:iAC20DED7D3138041
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
FM211187 Genomic DNA. Translation: CAR69359.1.
RefSeqiYP_002511478.1. NC_011900.1.

Genome annotation databases

EnsemblBacteriaiCAR69359; CAR69359; SPN23F15810.
GeneIDi7328792.
KEGGisne:SPN23F_15810.
PATRICi19674520. VBIStrPne132160_1662.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
FM211187 Genomic DNA. Translation: CAR69359.1 .
RefSeqi YP_002511478.1. NC_011900.1.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 561276.SPN23F_15810.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai CAR69359 ; CAR69359 ; SPN23F15810 .
GeneIDi 7328792.
KEGGi sne:SPN23F_15810.
PATRICi 19674520. VBIStrPne132160_1662.

Phylogenomic databases

eggNOGi COG1481.
KOi K09762.
OMAi HKFMLDA.
OrthoDBi EOG68WR87.

Enzyme and pathway databases

BioCyci SPNE561276:GJFJ-1516-MONOMER.

Family and domain databases

Gene3Di 3.10.28.10. 1 hit.
HAMAPi MF_01420. HTH_type_WhiA.
InterProi IPR027434. Homing_endonucl.
IPR018478. Sporu_reg_WhiA_N_dom.
IPR003802. Sporulation_regulator_WhiA.
IPR023054. Sporulation_regulator_WhiA_C.
[Graphical view ]
Pfami PF02650. HTH_WhiA. 1 hit.
PF10298. WhiA_N. 1 hit.
[Graphical view ]
SUPFAMi SSF55608. SSF55608. 1 hit.
TIGRFAMsi TIGR00647. MG103. 1 hit.
ProtoNeti Search...

Publicationsi

  1. "Role of conjugative elements in the evolution of the multidrug-resistant pandemic clone Streptococcus pneumoniae Spain23F ST81."
    Croucher N.J., Walker D., Romero P., Lennard N., Paterson G.K., Bason N.C., Mitchell A.M., Quail M.A., Andrew P.W., Parkhill J., Bentley S.D., Mitchell T.J.
    J. Bacteriol. 191:1480-1489(2009) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 700669 / Spain 23F-1.

Entry informationi

Entry nameiWHIA_STRPJ
AccessioniPrimary (citable) accession number: B8ZLS6
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 26, 2009
Last sequence update: March 3, 2009
Last modified: October 1, 2014
This is version 42 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3