B8ZLS6 (WHIA_STRPJ) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Putative sporulation transcription regulator WhiA

Gene names

Name:	whiA
Ordered Locus Names:	SPN23F15810

Organism

Streptococcus pneumoniae (strain ATCC 700669 / Spain 23F-1) [Complete proteome] [HAMAP]

Taxonomic identifier

561276 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Firmicutes › Bacilli › Lactobacillales › Streptococcaceae › Streptococcus › Streptococcus pneumoniae

Protein attributes

Sequence length	303 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	May be required for sporulation By similarity.
Sequence similarities	Belongs to the WhiA transcriptional regulatory family.

Ontologies

Keywords
Biological process	Transcription Transcription regulation
Ligand	DNA-binding
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	regulation of sporulation Inferred from electronic annotation. Source: HAMAP regulation of transcription, DNA-dependent Inferred from electronic annotation. Source: UniProtKB-KW transcription, DNA-dependent Inferred from electronic annotation. Source: UniProtKB-KW
Molecular_function	DNA binding Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 303	303	Putative sporulation transcription regulator WhiA HAMAP-Rule MF_01420		PRO_0000376577
Regions
	DNA binding	272 – 303	32	H-T-H motif Potential

Sequences

	Sequence		Length	Mass (Da)
	B8ZLS6 [UniParc]. Last modified March 3, 2009. Version 1. Checksum: AC20DED7D3138041	FASTA	303	34,062
	10 20 30 40 50 60 MSFTVAVKEE ILGQHHLSRH ELSAIIKMSG SIGLSTSGLT LSVVTENAKL ARHLYESFLH 70 80 90 100 110 120 FYEIKSEIRH HQRSNLRKNR VYTVFTDEKV QDLLSDLHLA DSFFGLETGI DEAILSDEEA 130 140 150 160 170 180 GRAYLCGAFL ANGSIRDPES GKYQLEISSV YLDHAQGIAS LLQQFLLDAK VLERKKGAVT 190 200 210 220 230 240 YLQRAEDIMD FLIVIGAMQA RDDFERVKIL RETRNDLNRA NNAETANIAR TVSASMKTIN 250 260 270 280 290 300 NISKIKDIMG LENLPVDLQE VAQLRIQHPD YSIQQLADSL STPLTKSGVN HRLRKINKIA DEL

References

[1]

"Role of conjugative elements in the evolution of the multidrug-resistant pandemic clone Streptococcus pneumoniae Spain23F ST81." Croucher N.J., Walker D., Romero P., Lennard N., Paterson G.K., Bason N.C., Mitchell A.M., Quail M.A., Andrew P.W., Parkhill J., Bentley S.D., Mitchell T.J. J. Bacteriol. 191:1480-1489(2009) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 700669 / Spain 23F-1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	FM211187 Genomic DNA. Translation: CAR69359.1.
RefSeq	YP_002511478.1. NC_011900.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	561276.SPN23F_15810.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	7328792.
KEGG	sne:SPN23F_15810.
PATRIC	19674520. VBIStrPne132160_1662.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG1481.
KO	K09762.
OMA	DSFFGIE.
ProtClustDB	CLSK877081.
Family and domain databases
HAMAP	MF_01420. HTH-type_WhiA.
InterPro	IPR003802. Sporulation_regulator_WhiA. IPR023054. Sporulation_regulator_WhiA_C. IPR018478. Sporulation_regulator_WhiA_N. [Graphical view]
Pfam	PF02650. HTH_WhiA. 1 hit. PF10298. WhiA_N. 1 hit. [Graphical view]
TIGRFAMs	TIGR00647. MG103. 1 hit.
ProtoNet	Search...

Entry information

Entry name

WHIA_STRPJ

Accession

Primary (citable) accession number: B8ZLS6

Entry history

Integrated into UniProtKB/Swiss-Prot:	May 26, 2009
Last sequence update:	March 3, 2009
Last modified:	May 1, 2013
This is version 32 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program