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Protein
Submitted name:

Putative sialidase (Neuraminidase)

Gene

SPN23F12180

Organism
Streptococcus pneumoniae (strain ATCC 700669 / Spain 23F-1)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein predictedi

Functioni

GO - Molecular functioni

  1. exo-alpha-sialidase activity Source: InterPro

GO - Biological processi

  1. carbohydrate metabolic process Source: InterPro
Complete GO annotation...

Enzyme and pathway databases

BioCyciSPNE561276:GJFJ-1178-MONOMER.

Names & Taxonomyi

Protein namesi
Submitted name:
Putative sialidase (Neuraminidase)Imported
Gene namesi
Ordered Locus Names:SPN23F12180Imported
OrganismiStreptococcus pneumoniae (strain ATCC 700669 / Spain 23F-1)Imported
Taxonomic identifieri561276 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliLactobacillalesStreptococcaceaeStreptococcus
ProteomesiUP000002600 Componenti: Chromosome

Interactioni

Protein-protein interaction databases

STRINGi561276.SPN23F_12180.

Family & Domainsi

Phylogenomic databases

eggNOGiCOG4409.
KOiK01186.
OMAiSISEVQH.
OrthoDBiEOG61CM2G.

Family and domain databases

Gene3Di2.120.10.10. 2 hits.
2.40.220.10. 1 hit.
2.60.120.200. 1 hit.
InterProiIPR002860. BNR_rpt.
IPR013320. ConA-like_dom.
IPR004124. Glyco_hydro_33_N.
IPR026856. Sialidase_fam.
IPR011040. Sialidases.
IPR023364. Trans_sialidase_dom3.
[Graphical view]
PANTHERiPTHR10628. PTHR10628. 1 hit.
PfamiPF02012. BNR. 1 hit.
PF02973. Sialidase. 1 hit.
[Graphical view]
SUPFAMiSSF49899. SSF49899. 1 hit.
SSF50939. SSF50939. 2 hits.

Sequencei

Sequence statusi: Complete.

B8ZK40-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKKNIKQYVT LGTVVVLSAF VANSVAAQET ETSEVSTPEL VQPVAPTTSI
60 70 80 90 100
SEVQHKSGNS SEVTVQPRTV ETTVKDPSST AEETPVLEKN NVTLTGGGEN
110 120 130 140 150
VTNELKDKFT SGDFTVVIKY NQSSEKGLQA LFGISNSKPG QQNSYVDVFL
160 170 180 190 200
RDNGELGMEA RDTSSNKNHL VTRPASVWGK YKQEAVTNTV AVVADSVKKT
210 220 230 240 250
YSLYANGTKV VEKKVDNFLN IKDIKGIDYY MLGGVKRAGK TAFGFNGTLE
260 270 280 290 300
NIKFFNSALD EETVKKMTTN AVTGHLIYTA NDTTGSNYFR IPVLYTFSNG
310 320 330 340 350
RVFSSIDARY GGTHDFLNKI NIATSYSDDN GKTWTKPKLT LAFDDFAPAP
360 370 380 390 400
LEWPRDVGGR DLQISGGATY IDSVIVEKNN KQVLMFADVM PAGVSFREAT
410 420 430 440 450
RKDSGYKQID GNYYLKLKKQ GDTDYNYTIR EHGTVYDDRT NRPTEFSVDK
460 470 480 490 500
NFGIKQNGNY LTVEQYSVSF ENNKKTEYRN GTQVHMNIFY KDALFKVVPT
510 520 530 540 550
NYIAYISSND HGESWSAPTL LPPIMGLNRN APYLGPGRGI IESSTGRILI
560 570 580 590 600
PSYTGKESAF IYSDDNGASW KVKVVPLPSS WSAEAQFVEL SPGVIQAYMR
610 620 630 640 650
TNNGKIAYLT SKDAGTTWSA PEYLKFVSNP SYGTQLSIIN YSQLIDGKKA
660 670 680 690 700
VILSTPNSTN GRKHGQISIG LINDDNTIDW RYHHDVDYSN YGYSYSTLTE
710 720 730 740
LPNHEIGLMF EKFDSWSRNE LHMKNVVPYI TFKIEDLKKN
Length:740
Mass (Da):82,300
Last modified:March 3, 2009 - v1
Checksum:i882B1AE8D71AF412
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
FM211187 Genomic DNA. Translation: CAR69021.1.
RefSeqiYP_002511153.1. NC_011900.1.

Genome annotation databases

EnsemblBacteriaiCAR69021; CAR69021; SPN23F12180.
GeneIDi7327735.
KEGGisne:SPN23F_12180.
PATRICi19673790. VBIStrPne132160_1296.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
FM211187 Genomic DNA. Translation: CAR69021.1.
RefSeqiYP_002511153.1. NC_011900.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi561276.SPN23F_12180.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiCAR69021; CAR69021; SPN23F12180.
GeneIDi7327735.
KEGGisne:SPN23F_12180.
PATRICi19673790. VBIStrPne132160_1296.

Phylogenomic databases

eggNOGiCOG4409.
KOiK01186.
OMAiSISEVQH.
OrthoDBiEOG61CM2G.

Enzyme and pathway databases

BioCyciSPNE561276:GJFJ-1178-MONOMER.

Family and domain databases

Gene3Di2.120.10.10. 2 hits.
2.40.220.10. 1 hit.
2.60.120.200. 1 hit.
InterProiIPR002860. BNR_rpt.
IPR013320. ConA-like_dom.
IPR004124. Glyco_hydro_33_N.
IPR026856. Sialidase_fam.
IPR011040. Sialidases.
IPR023364. Trans_sialidase_dom3.
[Graphical view]
PANTHERiPTHR10628. PTHR10628. 1 hit.
PfamiPF02012. BNR. 1 hit.
PF02973. Sialidase. 1 hit.
[Graphical view]
SUPFAMiSSF49899. SSF49899. 1 hit.
SSF50939. SSF50939. 2 hits.
ProtoNetiSearch...

Publicationsi

  1. "Role of conjugative elements in the evolution of the multidrug-resistant pandemic clone Streptococcus pneumoniae Spain23F ST81."
    Croucher N.J., Walker D., Romero P., Lennard N., Paterson G.K., Bason N.C., Mitchell A.M., Quail M.A., Andrew P.W., Parkhill J., Bentley S.D., Mitchell T.J.
    J. Bacteriol. 191:1480-1489(2008) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 700669 / Spain 23F-1Imported.

Entry informationi

Entry nameiB8ZK40_STRPJ
AccessioniPrimary (citable) accession number: B8ZK40
Entry historyi
Integrated into UniProtKB/TrEMBL: March 3, 2009
Last sequence update: March 3, 2009
Last modified: April 1, 2015
This is version 41 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.