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B8ZK06

- B8ZK06_STRPJ

UniProt

B8ZK06 - B8ZK06_STRPJ

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Protein

tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG

Gene
mnmG, gidA, SPN23F01340
Organism
Streptococcus pneumoniae (strain ATCC 700669 / Spain 23F-1)
Status
Unreviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm5s2U34 By similarity.UniRule annotation

Cofactori

FAD By similarity.UniRule annotationSAAS annotations

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei127 – 1271FAD; via amide nitrogen and carbonyl oxygen By similarityUniRule annotation
Binding sitei182 – 1821FAD By similarityUniRule annotation
Binding sitei373 – 3731FAD By similarityUniRule annotation

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi15 – 206FAD By similarityUniRule annotation
Nucleotide bindingi276 – 29015NAD By similarityUniRule annotationAdd
BLAST

GO - Molecular functioni

  1. flavin adenine dinucleotide binding Source: UniProtKB-HAMAP

GO - Biological processi

  1. tRNA wobble uridine modification Source: InterPro
Complete GO annotation...

Keywords - Biological processi

tRNA processingUniRule annotation

Keywords - Ligandi

FADUniRule annotationSAAS annotations, Flavoprotein, NADUniRule annotation

Enzyme and pathway databases

BioCyciSPNE561276:GJFJ-133-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmGUniRule annotation
Alternative name(s):
Glucose-inhibited division protein A
Gene namesi
Name:mnmGUniRule annotation
Synonyms:gidAUniRule annotationImported
Ordered Locus Names:SPN23F01340Imported
OrganismiStreptococcus pneumoniae (strain ATCC 700669 / Spain 23F-1)Imported
Taxonomic identifieri561276 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliLactobacillalesStreptococcaceaeStreptococcus
ProteomesiUP000002600: Chromosome

Subcellular locationi

Cytoplasm By similarity UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

CytoplasmUniRule annotation

Interactioni

Subunit structurei

Homodimer. Heterotetramer of two MnmE and two MnmG subunits By similarity.UniRule annotation

Protein-protein interaction databases

STRINGi561276.SPN23F_01340.

Structurei

3D structure databases

ProteinModelPortaliB8ZK06.

Family & Domainsi

Sequence similaritiesi

Belongs to the MnmG family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0445.
KOiK03495.
OMAiFHIEREQ.
OrthoDBiEOG6W9X6J.

Family and domain databases

HAMAPiMF_00129. MnmG_GidA.
InterProiIPR004416. GidA.
IPR026904. GidA-assoc_3.
IPR002218. GIDA-rel.
IPR020595. GIDA-rel_CS.
[Graphical view]
PfamiPF01134. GIDA. 1 hit.
PF13932. GIDA_assoc_3. 1 hit.
[Graphical view]
TIGRFAMsiTIGR00136. gidA. 1 hit.
PROSITEiPS01280. GIDA_1. 1 hit.
PS01281. GIDA_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

B8ZK06-1 [UniParc]FASTAAdd to Basket

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MTYHFTEEYD IIVIGAGHAG VEASLAASRM GCKVLLATIN IEMLAFMPCN    50
PSIGGSAKGI VVREVDALGG EMAKTIDKTY IQMKMLNTGK GPAVRALRAQ 100
ADKELYSKEM RKTVENQENL TLRQTMIDEI LVEDGKVVGV RTATHQEYAA 150
KAVIVTTGTA LRGEIIIGDL KYSSGPNHSL ASINLADNLK ELGLEIGRFK 200
TGTPPRVKAS SINYDVTEIQ PGDEAPNHFS YTSRDEDYVK DQVPCWLTYT 250
NGTSHEIIQN NLHRAPMFTG VVKGVGPRYC PSIEDKIVRF ADKERHQLFL 300
EPEGRNTEEV YVQGLSTSLP EDVQRDLVHS IKGLENAEMM RTGYAIEYDM 350
ILPHQLRATL ETKKISGLFT AGQTNGTSGY EEAAGQGIIA GINAALKIQD 400
KPELILKRSD GYIGVMIDDL VTKGTIEPYR LLTSRAEYRL ILRHDNADMR 450
LTEMGREIGL VDDERWARFE IKKNQFDNEM KRLDSIKLKP VKETNAKVEE 500
MGFKPLTDAV TAKEFLRRPE VSYQDVVAFI GPAAEDLDDK IIELIETEIK 550
YEGYISKAMD QVAKMKRMEE KRIPANIDWD DIDSIATEAR QKFKLINPET 600
IGQASRISGV NPADISILMV YLEGKNRSIS KTLQKSK 637
Length:637
Mass (Da):71,090
Last modified:March 3, 2009 - v1
Checksum:i3C8D319632A8B944
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
FM211187 Genomic DNA. Translation: CAR67992.1.
RefSeqiYP_002510204.1. NC_011900.1.

Genome annotation databases

EnsemblBacteriaiCAR67992; CAR67992; SPN23F01340.
GeneIDi7329091.
KEGGisne:SPN23F_01340.
PATRICi19671479. VBIStrPne132160_0142.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
FM211187 Genomic DNA. Translation: CAR67992.1 .
RefSeqi YP_002510204.1. NC_011900.1.

3D structure databases

ProteinModelPortali B8ZK06.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 561276.SPN23F_01340.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai CAR67992 ; CAR67992 ; SPN23F01340 .
GeneIDi 7329091.
KEGGi sne:SPN23F_01340.
PATRICi 19671479. VBIStrPne132160_0142.

Phylogenomic databases

eggNOGi COG0445.
KOi K03495.
OMAi FHIEREQ.
OrthoDBi EOG6W9X6J.

Enzyme and pathway databases

BioCyci SPNE561276:GJFJ-133-MONOMER.

Family and domain databases

HAMAPi MF_00129. MnmG_GidA.
InterProi IPR004416. GidA.
IPR026904. GidA-assoc_3.
IPR002218. GIDA-rel.
IPR020595. GIDA-rel_CS.
[Graphical view ]
Pfami PF01134. GIDA. 1 hit.
PF13932. GIDA_assoc_3. 1 hit.
[Graphical view ]
TIGRFAMsi TIGR00136. gidA. 1 hit.
PROSITEi PS01280. GIDA_1. 1 hit.
PS01281. GIDA_2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Role of conjugative elements in the evolution of the multidrug-resistant pandemic clone Streptococcus pneumoniae Spain23F ST81."
    Croucher N.J., Walker D., Romero P., Lennard N., Paterson G.K., Bason N.C., Mitchell A.M., Quail M.A., Andrew P.W., Parkhill J., Bentley S.D., Mitchell T.J.
    J. Bacteriol. 191:1480-1489(2009) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 700669 / Spain 23F-1.

Entry informationi

Entry nameiB8ZK06_STRPJ
AccessioniPrimary (citable) accession number: B8ZK06
Entry historyi
Integrated into UniProtKB/TrEMBL: March 3, 2009
Last sequence update: March 3, 2009
Last modified: June 11, 2014
This is version 38 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome

External Data

Dasty 3

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