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B8ZK06 (B8ZK06_STRPJ) Unreviewed, UniProtKB/TrEMBL

Last modified June 11, 2014. Version 38. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize order

Names and origin

Protein namesRecommended name:
tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG HAMAP-Rule MF_00129
Alternative name(s):
Glucose-inhibited division protein A HAMAP-Rule MF_00129
Gene names
Name:mnmG HAMAP-Rule MF_00129
Synonyms:gidA HAMAP-Rule MF_00129 EMBL CAR67992.1
Ordered Locus Names:SPN23F01340 EMBL CAR67992.1
OrganismStreptococcus pneumoniae (strain ATCC 700669 / Spain 23F-1) [Complete proteome] [HAMAP] EMBL CAR67992.1
Taxonomic identifier561276 [NCBI]
Taxonomic lineageBacteriaFirmicutesBacilliLactobacillalesStreptococcaceaeStreptococcus

Protein attributes

Sequence length637 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm5s2U34 By similarity. HAMAP-Rule MF_00129

Cofactor

FAD By similarity. HAMAP-Rule MF_00129 SAAS SAAS026904

Subunit structure

Homodimer. Heterotetramer of two MnmE and two MnmG subunits By similarity. HAMAP-Rule MF_00129

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00129.

Sequence similarities

Belongs to the MnmG family. HAMAP-Rule MF_00129

Ontologies

Keywords
   Biological processtRNA processing HAMAP-Rule MF_00129
   Cellular componentCytoplasm HAMAP-Rule MF_00129
   LigandFAD HAMAP-Rule MF_00129 SAAS SAAS026904
Flavoprotein
NAD HAMAP-Rule MF_00129
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processtRNA wobble uridine modification

Inferred from electronic annotation. Source: InterPro

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionflavin adenine dinucleotide binding

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Regions

Nucleotide binding15 – 206FAD By similarity HAMAP-Rule MF_00129
Nucleotide binding276 – 29015NAD By similarity HAMAP-Rule MF_00129

Sites

Binding site1271FAD; via amide nitrogen and carbonyl oxygen By similarity HAMAP-Rule MF_00129
Binding site1821FAD By similarity HAMAP-Rule MF_00129
Binding site3731FAD By similarity HAMAP-Rule MF_00129

Sequences

Sequence LengthMass (Da)Tools
B8ZK06 [UniParc].

Last modified March 3, 2009. Version 1.
Checksum: 3C8D319632A8B944

FASTA63771,090
        10         20         30         40         50         60 
MTYHFTEEYD IIVIGAGHAG VEASLAASRM GCKVLLATIN IEMLAFMPCN PSIGGSAKGI 

        70         80         90        100        110        120 
VVREVDALGG EMAKTIDKTY IQMKMLNTGK GPAVRALRAQ ADKELYSKEM RKTVENQENL 

       130        140        150        160        170        180 
TLRQTMIDEI LVEDGKVVGV RTATHQEYAA KAVIVTTGTA LRGEIIIGDL KYSSGPNHSL 

       190        200        210        220        230        240 
ASINLADNLK ELGLEIGRFK TGTPPRVKAS SINYDVTEIQ PGDEAPNHFS YTSRDEDYVK 

       250        260        270        280        290        300 
DQVPCWLTYT NGTSHEIIQN NLHRAPMFTG VVKGVGPRYC PSIEDKIVRF ADKERHQLFL 

       310        320        330        340        350        360 
EPEGRNTEEV YVQGLSTSLP EDVQRDLVHS IKGLENAEMM RTGYAIEYDM ILPHQLRATL 

       370        380        390        400        410        420 
ETKKISGLFT AGQTNGTSGY EEAAGQGIIA GINAALKIQD KPELILKRSD GYIGVMIDDL 

       430        440        450        460        470        480 
VTKGTIEPYR LLTSRAEYRL ILRHDNADMR LTEMGREIGL VDDERWARFE IKKNQFDNEM 

       490        500        510        520        530        540 
KRLDSIKLKP VKETNAKVEE MGFKPLTDAV TAKEFLRRPE VSYQDVVAFI GPAAEDLDDK 

       550        560        570        580        590        600 
IIELIETEIK YEGYISKAMD QVAKMKRMEE KRIPANIDWD DIDSIATEAR QKFKLINPET 

       610        620        630 
IGQASRISGV NPADISILMV YLEGKNRSIS KTLQKSK 

« Hide

References

[1]"Role of conjugative elements in the evolution of the multidrug-resistant pandemic clone Streptococcus pneumoniae Spain23F ST81."
Croucher N.J., Walker D., Romero P., Lennard N., Paterson G.K., Bason N.C., Mitchell A.M., Quail M.A., Andrew P.W., Parkhill J., Bentley S.D., Mitchell T.J.
J. Bacteriol. 191:1480-1489(2009) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 700669 / Spain 23F-1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
FM211187 Genomic DNA. Translation: CAR67992.1.
RefSeqYP_002510204.1. NC_011900.1.

3D structure databases

ProteinModelPortalB8ZK06.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING561276.SPN23F_01340.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaCAR67992; CAR67992; SPN23F01340.
GeneID7329091.
KEGGsne:SPN23F_01340.
PATRIC19671479. VBIStrPne132160_0142.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0445.
KOK03495.
OMAFHIEREQ.
OrthoDBEOG6W9X6J.

Enzyme and pathway databases

BioCycSPNE561276:GJFJ-133-MONOMER.

Family and domain databases

HAMAPMF_00129. MnmG_GidA.
InterProIPR004416. GidA.
IPR026904. GidA-assoc_3.
IPR002218. GIDA-rel.
IPR020595. GIDA-rel_CS.
[Graphical view]
PfamPF01134. GIDA. 1 hit.
PF13932. GIDA_assoc_3. 1 hit.
[Graphical view]
TIGRFAMsTIGR00136. gidA. 1 hit.
PROSITEPS01280. GIDA_1. 1 hit.
PS01281. GIDA_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameB8ZK06_STRPJ
AccessionPrimary (citable) accession number: B8ZK06
Entry history
Integrated into UniProtKB/TrEMBL: March 3, 2009
Last sequence update: March 3, 2009
Last modified: June 11, 2014
This is version 38 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)