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B8ZK06

- B8ZK06_STRPJ

UniProt

B8ZK06 - B8ZK06_STRPJ

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Protein

tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG

Gene

mnmG

Organism
Streptococcus pneumoniae (strain ATCC 700669 / Spain 23F-1)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm5s2U34.UniRule annotation

Cofactori

Note: FAD.UniRule annotationSAAS annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei127 – 1271FAD; via amide nitrogen and carbonyl oxygenUniRule annotation
Binding sitei182 – 1821FADUniRule annotation
Binding sitei373 – 3731FADUniRule annotation

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi15 – 206FADUniRule annotation
Nucleotide bindingi276 – 29015NADUniRule annotationAdd
BLAST

GO - Molecular functioni

  1. flavin adenine dinucleotide binding Source: UniProtKB-HAMAP

GO - Biological processi

  1. tRNA wobble uridine modification Source: InterPro
Complete GO annotation...

Keywords - Biological processi

tRNA processingUniRule annotation

Keywords - Ligandi

FADUniRule annotationSAAS annotation, Flavoprotein, NADUniRule annotation

Enzyme and pathway databases

BioCyciSPNE561276:GJFJ-133-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmGUniRule annotation
Alternative name(s):
Glucose-inhibited division protein AUniRule annotation
Gene namesi
Name:mnmGUniRule annotation
Synonyms:gidAUniRule annotationImported
Ordered Locus Names:SPN23F01340Imported
OrganismiStreptococcus pneumoniae (strain ATCC 700669 / Spain 23F-1)Imported
Taxonomic identifieri561276 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliLactobacillalesStreptococcaceaeStreptococcus
ProteomesiUP000002600: Chromosome

Subcellular locationi

Cytoplasm UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

CytoplasmUniRule annotation

Interactioni

Subunit structurei

Homodimer. Heterotetramer of two MnmE and two MnmG subunits.UniRule annotation

Protein-protein interaction databases

STRINGi561276.SPN23F_01340.

Structurei

3D structure databases

ProteinModelPortaliB8ZK06.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the MnmG family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0445.
KOiK03495.
OMAiFHIEREQ.
OrthoDBiEOG6W9X6J.

Family and domain databases

HAMAPiMF_00129. MnmG_GidA.
InterProiIPR004416. GidA.
IPR026904. GidA-assoc_3.
IPR002218. GIDA-rel.
IPR020595. GIDA-rel_CS.
[Graphical view]
PfamiPF01134. GIDA. 1 hit.
PF13932. GIDA_assoc_3. 1 hit.
[Graphical view]
TIGRFAMsiTIGR00136. gidA. 1 hit.
PROSITEiPS01280. GIDA_1. 1 hit.
PS01281. GIDA_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

B8ZK06-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MTYHFTEEYD IIVIGAGHAG VEASLAASRM GCKVLLATIN IEMLAFMPCN
60 70 80 90 100
PSIGGSAKGI VVREVDALGG EMAKTIDKTY IQMKMLNTGK GPAVRALRAQ
110 120 130 140 150
ADKELYSKEM RKTVENQENL TLRQTMIDEI LVEDGKVVGV RTATHQEYAA
160 170 180 190 200
KAVIVTTGTA LRGEIIIGDL KYSSGPNHSL ASINLADNLK ELGLEIGRFK
210 220 230 240 250
TGTPPRVKAS SINYDVTEIQ PGDEAPNHFS YTSRDEDYVK DQVPCWLTYT
260 270 280 290 300
NGTSHEIIQN NLHRAPMFTG VVKGVGPRYC PSIEDKIVRF ADKERHQLFL
310 320 330 340 350
EPEGRNTEEV YVQGLSTSLP EDVQRDLVHS IKGLENAEMM RTGYAIEYDM
360 370 380 390 400
ILPHQLRATL ETKKISGLFT AGQTNGTSGY EEAAGQGIIA GINAALKIQD
410 420 430 440 450
KPELILKRSD GYIGVMIDDL VTKGTIEPYR LLTSRAEYRL ILRHDNADMR
460 470 480 490 500
LTEMGREIGL VDDERWARFE IKKNQFDNEM KRLDSIKLKP VKETNAKVEE
510 520 530 540 550
MGFKPLTDAV TAKEFLRRPE VSYQDVVAFI GPAAEDLDDK IIELIETEIK
560 570 580 590 600
YEGYISKAMD QVAKMKRMEE KRIPANIDWD DIDSIATEAR QKFKLINPET
610 620 630
IGQASRISGV NPADISILMV YLEGKNRSIS KTLQKSK
Length:637
Mass (Da):71,090
Last modified:March 3, 2009 - v1
Checksum:i3C8D319632A8B944
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
FM211187 Genomic DNA. Translation: CAR67992.1.
RefSeqiYP_002510204.1. NC_011900.1.

Genome annotation databases

EnsemblBacteriaiCAR67992; CAR67992; SPN23F01340.
GeneIDi7329091.
KEGGisne:SPN23F_01340.
PATRICi19671479. VBIStrPne132160_0142.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
FM211187 Genomic DNA. Translation: CAR67992.1 .
RefSeqi YP_002510204.1. NC_011900.1.

3D structure databases

ProteinModelPortali B8ZK06.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 561276.SPN23F_01340.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai CAR67992 ; CAR67992 ; SPN23F01340 .
GeneIDi 7329091.
KEGGi sne:SPN23F_01340.
PATRICi 19671479. VBIStrPne132160_0142.

Phylogenomic databases

eggNOGi COG0445.
KOi K03495.
OMAi FHIEREQ.
OrthoDBi EOG6W9X6J.

Enzyme and pathway databases

BioCyci SPNE561276:GJFJ-133-MONOMER.

Family and domain databases

HAMAPi MF_00129. MnmG_GidA.
InterProi IPR004416. GidA.
IPR026904. GidA-assoc_3.
IPR002218. GIDA-rel.
IPR020595. GIDA-rel_CS.
[Graphical view ]
Pfami PF01134. GIDA. 1 hit.
PF13932. GIDA_assoc_3. 1 hit.
[Graphical view ]
TIGRFAMsi TIGR00136. gidA. 1 hit.
PROSITEi PS01280. GIDA_1. 1 hit.
PS01281. GIDA_2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Role of conjugative elements in the evolution of the multidrug-resistant pandemic clone Streptococcus pneumoniae Spain23F ST81."
    Croucher N.J., Walker D., Romero P., Lennard N., Paterson G.K., Bason N.C., Mitchell A.M., Quail M.A., Andrew P.W., Parkhill J., Bentley S.D., Mitchell T.J.
    J. Bacteriol. 191:1480-1489(2009) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 700669 / Spain 23F-1Imported.

Entry informationi

Entry nameiB8ZK06_STRPJ
AccessioniPrimary (citable) accession number: B8ZK06
Entry historyi
Integrated into UniProtKB/TrEMBL: March 3, 2009
Last sequence update: March 3, 2009
Last modified: November 26, 2014
This is version 41 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

External Data

Dasty 3