B8Y3M1 (B8Y3M1_ONCMY) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Liver X receptor EMBL ACK99548.1

Gene names

Name:

LXR EMBL ACK99548.1

Organism

Oncorhynchus mykiss (Rainbow trout) (Salmo gairdneri) EMBL ACK99548.1

Taxonomic identifier

8022 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Actinopterygii › Actinopteri › Neopterygii › Teleostei › Elopocephala › Clupeocephala › Euteleostei › Protacanthopterygii › Salmoniformes › Salmonoidei › Salmonidae › Salmoninae › Oncorhynchus

Protein attributes

Sequence length	462 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

General annotation (Comments)

Sequence similarities

Belongs to the nuclear hormone receptor family. RuleBase RU000377 Contains 1 nuclear receptor DNA-binding domain. SAAS SAAS000536

Ontologies

Keywords
Biological process	Transcription Transcription regulation RuleBase RU004334 SAAS SAAS000536
Cellular component	Nucleus RuleBase RU004334 SAAS SAAS000536
Domain	Zinc-finger RuleBase RU004334 SAAS SAAS000536
Ligand	DNA-binding RuleBase RU004334 SAAS SAAS000536 Metal-binding Zinc
Molecular function	Receptor RuleBase RU004334 EMBL ACK99548.1
Gene Ontology (GO)
Biological_process	transcription, DNA-dependent Inferred from electronic annotation. Source: UniProtKB-KW
Cellular_component	nucleus Inferred from electronic annotation. Source: UniProtKB-KW
Molecular_function	sequence-specific DNA binding Inferred from electronic annotation. Source: InterPro sequence-specific DNA binding transcription factor activity Inferred from electronic annotation. Source: InterPro steroid hormone receptor activity Inferred from electronic annotation. Source: InterPro zinc ion binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	B8Y3M1 [UniParc]. Last modified March 3, 2009. Version 1. Checksum: 4B2AE7A90913C8DF	FASTA	462	52,346
	10 20 30 40 50 60 MSTLSATDIT DVGPGEVFDG APELQLDCFC SGDGRSSAEM KHEGNLLPLE PPDHAGFSSS 70 80 90 100 110 120 PQKRPSSLAE ESSPLPMEPS DIKADPAGSM PANTEGQPVK RKKGPAPKML GNEVCSVCGD 130 140 150 160 170 180 KASGFHYNVL SCEGCKGFFR RSVIKSAQYS CKNNGRCEMD MYMRRKCQQC RLRKCREAGM 190 200 210 220 230 240 LEQCVLSEEQ IRVKKMKKNE EETARTSAVV TPTPVPEVVP LAPEQLEMIE KLVAMRKQCN 250 260 270 280 290 300 KRSFIDRPKV TPWPQSQDPQ NREVRQQRFA HFTELAIMSV QEIVDFAKQL PGFLELTRED 310 320 330 340 350 360 QIALLKTSTI EIMLLETSRR YNPAIESITF LKDFSYNKED FAKAGLQLEF INPIFEFSKG 370 380 390 400 410 420 MNDLHLDEAE YALLIAINIF SADRPNVQDH ELVERLQQPY VDALRSYIMI KRPNDHLMFP 430 440 450 460 RMLMKLVSLR TLSSVHSEQV FALRLQDKKL PPLLSEIWDV HE

References

[1]	Cruz Garcia L., Minghetti M., Navarro I., Tocher D.R. Submitted (NOV-2008) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE.
[2]	"Molecular cloning, tissue expression and regulation of liver X Receptor (LXR) transcription factors of Atlantic salmon (Salmo salar) and rainbow trout (Oncorhynchus mykiss)." Cruz-Garcia L., Minghetti M., Navarro I., Tocher D.R. Comp. Biochem. Physiol. B, Biochem. Mol. Biol. 153:81-88(2009) Cited for: NUCLEOTIDE SEQUENCE.

Cross-references

Sequence databases
EMBL GenBank DDBJ	FJ470291 mRNA. Translation: ACK99548.1.
RefSeq	NP_001152810.1. NM_001159338.1.
UniGene	Omy.35986.
3D structure databases
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	100286817.
Organism-specific databases
CTD	10062.
Phylogenomic databases
HOVERGEN	HBG108655.
Family and domain databases
Gene3D	1.10.565.10. 2 hits. 3.30.50.10. 1 hit.
InterPro	IPR023257. Liver_X_rcpt. IPR008946. Nucl_hormone_rcpt_ligand-bd. IPR000536. Nucl_hrmn_rcpt_lig-bd_core. IPR001723. Str_hrmn_rcpt. IPR001368. TNFR/NGFR_Cys_rich_reg. IPR001628. Znf_hrmn_rcpt. IPR013088. Znf_NHR/GATA. [Graphical view]
Pfam	PF00104. Hormone_recep. 1 hit. PF00105. zf-C4. 1 hit. [Graphical view]
PRINTS	PR02034. LIVERXRECPTR. PR00398. STRDHORMONER. PR00047. STROIDFINGER.
SMART	SM00430. HOLI. 1 hit. SM00208. TNFR. 1 hit. SM00399. ZnF_C4. 1 hit. [Graphical view]
SUPFAM	SSF48508. Str_ncl_receptor. 1 hit.
PROSITE	PS00031. NUCLEAR_REC_DBD_1. 1 hit. PS51030. NUCLEAR_REC_DBD_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

B8Y3M1_ONCMY

Accession

Primary (citable) accession number: B8Y3M1

Entry history

Integrated into UniProtKB/TrEMBL:	March 3, 2009
Last sequence update:	March 3, 2009
Last modified:	April 3, 2013
This is version 28 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)