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B8XH40

- KBX1_BUTOS

UniProt

B8XH40 - KBX1_BUTOS

Protein

Potassium channel toxin BuTXK-beta

Gene
N/A
Organism
Buthus occitanus israelis (Common yellow scorpion)
Status
Reviewed - Annotation score: 2 out of 5- Experimental evidence at transcript leveli
  1. Functioni

    Blocks voltage-gated potassium channels.By similarity

    GO - Biological processi

    1. defense response Source: InterPro

    Keywords - Molecular functioni

    Ion channel impairing toxin, Neurotoxin, Potassium channel impairing toxin, Toxin

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Potassium channel toxin BuTXK-beta
    Short name:
    BuTXKbeta
    Alternative name(s):
    Potassium channel toxin Tx690
    OrganismiButhus occitanus israelis (Common yellow scorpion)
    Taxonomic identifieri539894 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaChelicerataArachnidaScorpionesButhidaButhoideaButhidaeButhus

    Subcellular locationi

    Secreted By similarity

    GO - Cellular componenti

    1. extracellular region Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Secreted

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Signal peptidei1 – 1919By similarityAdd
    BLAST
    Propeptidei20 – 278By similarityPRO_0000394024
    Chaini28 – 9164Potassium channel toxin BuTXK-betaPRO_0000394025Add
    BLAST

    Amino acid modifications

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Disulfide bondi57 ↔ 78By similarity
    Disulfide bondi64 ↔ 83By similarity
    Disulfide bondi68 ↔ 85By similarity

    Keywords - PTMi

    Disulfide bond

    Expressioni

    Tissue specificityi

    Expressed by the venom gland.

    Family & Domainsi

    Sequence similaritiesi

    Keywords - Domaini

    Signal

    Family and domain databases

    InterProiIPR029237. Long_scorpion_toxin.
    IPR003614. Scorpion_toxin-like.
    [Graphical view]
    PfamiPF14866. Toxin_38. 1 hit.
    [Graphical view]
    SMARTiSM00505. Knot1. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Sequence processingi: The displayed sequence is further processed into a mature form.

    B8XH40-1 [UniParc]FASTAAdd to Basket

    « Hide

    MQRNLVVLLL LGMVALSSCG LREKHFQKLV KYAVPESTLR TILQTAVHKL   50
    GKTQFGCPAY QGYCDDHCQD IKKEEGFCHG MKCKCGIPMG F 91
    Length:91
    Mass (Da):10,192
    Last modified:March 3, 2009 - v1
    Checksum:i75EC9BDEFA436D95
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    FJ360829 mRNA. Translation: ACJ23149.1.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    FJ360829 mRNA. Translation: ACJ23149.1 .

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Family and domain databases

    InterProi IPR029237. Long_scorpion_toxin.
    IPR003614. Scorpion_toxin-like.
    [Graphical view ]
    Pfami PF14866. Toxin_38. 1 hit.
    [Graphical view ]
    SMARTi SM00505. Knot1. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Buthus occitanus israelis scorpion toxin."
      Zilberberg N., Kozminsky-Atias A.
      Submitted (OCT-2008) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [MRNA].

    Entry informationi

    Entry nameiKBX1_BUTOS
    AccessioniPrimary (citable) accession number: B8XH40
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: May 18, 2010
    Last sequence update: March 3, 2009
    Last modified: October 1, 2014
    This is version 14 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programAnimal Toxin Annotation Program

    Miscellaneousi

    Documents

    1. Scorpion potassium channel toxins
      Nomenclature of scorpion potassium channel toxins and list of entries
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3