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B8XH40

- KBX1_BUTOS

UniProt

B8XH40 - KBX1_BUTOS

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Protein
Potassium channel toxin BuTXK-beta
Gene
N/A
Organism
Buthus occitanus israelis (Common yellow scorpion)
Status
Reviewed - Annotation score: 2 out of 5 - Experimental evidence at transcript leveli

Functioni

Blocks voltage-gated potassium channels By similarity.

GO - Biological processi

  1. defense response Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Ion channel impairing toxin, Neurotoxin, Potassium channel impairing toxin, Toxin

Names & Taxonomyi

Protein namesi
Recommended name:
Potassium channel toxin BuTXK-beta
Short name:
BuTXKbeta
Alternative name(s):
Potassium channel toxin Tx690
OrganismiButhus occitanus israelis (Common yellow scorpion)
Taxonomic identifieri539894 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaChelicerataArachnidaScorpionesButhidaButhoideaButhidaeButhus

Subcellular locationi

Secreted By similarity

GO - Cellular componenti

  1. extracellular region Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Secreted

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 1919 By similarity
Add
BLAST
Propeptidei20 – 278 By similarity
PRO_0000394024
Chaini28 – 9164Potassium channel toxin BuTXK-beta
PRO_0000394025Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Disulfide bondi57 ↔ 78 By similarity
Disulfide bondi64 ↔ 83 By similarity
Disulfide bondi68 ↔ 85 By similarity

Keywords - PTMi

Disulfide bond

Expressioni

Tissue specificityi

Expressed by the venom gland.

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Signal

Family and domain databases

InterProiIPR029237. Long_scorpion_toxin.
IPR003614. Scorpion_toxin-like.
[Graphical view]
PfamiPF14866. Toxin_38. 1 hit.
[Graphical view]
SMARTiSM00505. Knot1. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

B8XH40-1 [UniParc]FASTAAdd to Basket

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MQRNLVVLLL LGMVALSSCG LREKHFQKLV KYAVPESTLR TILQTAVHKL   50
GKTQFGCPAY QGYCDDHCQD IKKEEGFCHG MKCKCGIPMG F 91
Length:91
Mass (Da):10,192
Last modified:March 3, 2009 - v1
Checksum:i75EC9BDEFA436D95
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
FJ360829 mRNA. Translation: ACJ23149.1.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
FJ360829 mRNA. Translation: ACJ23149.1 .

3D structure databases

ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Family and domain databases

InterProi IPR029237. Long_scorpion_toxin.
IPR003614. Scorpion_toxin-like.
[Graphical view ]
Pfami PF14866. Toxin_38. 1 hit.
[Graphical view ]
SMARTi SM00505. Knot1. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Buthus occitanus israelis scorpion toxin."
    Zilberberg N., Kozminsky-Atias A.
    Submitted (OCT-2008) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [MRNA].

Entry informationi

Entry nameiKBX1_BUTOS
AccessioniPrimary (citable) accession number: B8XH40
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 18, 2010
Last sequence update: March 3, 2009
Last modified: July 9, 2014
This is version 13 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programAnimal Toxin Annotation Program

Miscellaneousi

Documents

  1. Scorpion potassium channel toxins
    Nomenclature of scorpion potassium channel toxins and list of entries
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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