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Protein
Submitted name:

CXC chemokine receptor 3

Gene

CXCR3

Organism
Macaca mulatta (Rhesus macaque)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionG-protein coupled receptorUniRule annotationSAAS annotation, Receptor, Transducer

Names & Taxonomyi

Protein namesi
Submitted name:
CXC chemokine receptor 3Imported
Gene namesi
Name:CXCR3Imported
OrganismiMacaca mulatta (Rhesus macaque)Imported
Taxonomic identifieri9544 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniCercopithecidaeCercopithecinaeMacaca

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei58 – 79HelicalSequence analysisAdd BLAST22
Transmembranei91 – 109HelicalSequence analysisAdd BLAST19
Transmembranei129 – 147HelicalSequence analysisAdd BLAST19
Transmembranei168 – 190HelicalSequence analysisAdd BLAST23
Transmembranei217 – 244HelicalSequence analysisAdd BLAST28
Transmembranei256 – 281HelicalSequence analysisAdd BLAST26
Transmembranei301 – 321HelicalSequence analysisAdd BLAST21

GO - Cellular componenti

Keywords - Cellular componenti

Membrane

Pathology & Biotechi

Chemistry databases

ChEMBLiCHEMBL1075186.

Interactioni

Chemistry databases

BindingDBiB8PY99.

Structurei

3D structure databases

ProteinModelPortaliB8PY99.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini70 – 318G_PROTEIN_RECEP_F1_2InterPro annotationAdd BLAST249

Sequence similaritiesi

Belongs to the G-protein coupled receptor 1 family.UniRule annotationSAAS annotation

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysisSAAS annotation

Phylogenomic databases

HOGENOMiHOG000234122.
HOVERGENiHBG106917.
KOiK04188.

Family and domain databases

InterProiView protein in InterPro
IPR004070. Chemokine_CXCR3.
IPR000355. Chemokine_rcpt.
IPR000276. GPCR_Rhodpsn.
IPR017452. GPCR_Rhodpsn_7TM.
PfamiView protein in Pfam
PF00001. 7tm_1. 1 hit.
PRINTSiPR00657. CCCHEMOKINER.
PR01532. CXCCHMKINER3.
PR00237. GPCRRHODOPSN.
PROSITEiView protein in PROSITE
PS00237. G_PROTEIN_RECEP_F1_1. 1 hit.
PS50262. G_PROTEIN_RECEP_F1_2. 1 hit.

Sequencei

Sequence statusi: Complete.

B8PY99-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVLEVSDHQV LNDAEVAALL ENFSSSYDYG ENESDSCCTS PPCPQDFSLN
60 70 80 90 100
FDRAFLPALY SLLFLLGLLG NGAVAAVLLS RRAALSSTDT FLLHLAVADT
110 120 130 140 150
LLVLTLPLWA VDAAVQWVFG SGLCKVAGAL FNINFYAGAL LLACISFDRY
160 170 180 190 200
LNIVHATQLY RRGPPARVTL TCLAVWGLCL LFALPDFIFL SAHHDERLNA
210 220 230 240 250
THCQYNFPQV GRTALRVLQL VAGFLLPLLV MAYCYAHILA VLLVSRGQRR
260 270 280 290 300
LRAMRLVVAV VVAFALCWTP YHLVVLVDIL MDLGALARNC GRESRVDVAK
310 320 330 340 350
SVTSGLGYMH CCLNPLLYAF VGVKFRERMW MLLLRLGCPN QRGLQRQPSS
360
SRRDSSWSET SEASYSGL
Length:368
Mass (Da):40,601
Last modified:March 3, 2009 - v1
Checksum:i078056EB41FD4D69
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
EU313340 mRNA. Translation: ABY56043.1.
RefSeqiNP_001138512.1. NM_001145040.1.
UniGeneiMmu.8534.

Genome annotation databases

GeneIDi699438.
KEGGimcc:699438.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
EU313340 mRNA. Translation: ABY56043.1.
RefSeqiNP_001138512.1. NM_001145040.1.
UniGeneiMmu.8534.

3D structure databases

ProteinModelPortaliB8PY99.
ModBaseiSearch...
MobiDBiSearch...

Chemistry databases

BindingDBiB8PY99.
ChEMBLiCHEMBL1075186.

Protein family/group databases

GPCRDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi699438.
KEGGimcc:699438.

Organism-specific databases

CTDi2833.

Phylogenomic databases

HOGENOMiHOG000234122.
HOVERGENiHBG106917.
KOiK04188.

Family and domain databases

InterProiView protein in InterPro
IPR004070. Chemokine_CXCR3.
IPR000355. Chemokine_rcpt.
IPR000276. GPCR_Rhodpsn.
IPR017452. GPCR_Rhodpsn_7TM.
PfamiView protein in Pfam
PF00001. 7tm_1. 1 hit.
PRINTSiPR00657. CCCHEMOKINER.
PR01532. CXCCHMKINER3.
PR00237. GPCRRHODOPSN.
PROSITEiView protein in PROSITE
PS00237. G_PROTEIN_RECEP_F1_1. 1 hit.
PS50262. G_PROTEIN_RECEP_F1_2. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiB8PY99_MACMU
AccessioniPrimary (citable) accession number: B8PY99
Entry historyiIntegrated into UniProtKB/TrEMBL: March 3, 2009
Last sequence update: March 3, 2009
Last modified: June 8, 2016
This is version 46 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.